Detection of extended spectrum B-lactamases in urinary isolates of Klebsiella pneumoniae in relation to Bla SHV, Bla TEM and Bla CTX-M gene carriage

Background: Resistance to contemporary broad-spectrum β-lactam antibiotics mediated by extended-spectrum β-lactamases (ESBLs) is increasing worldwide. Klebsiella pneumoniae, an important cause of nosocomial and community acquired urinary tract infections has rapidly become the most common ESBL producing organism. We examined ESBL production in urinary isolates of K. pneumoniae in relation to the presence of bla SHV, bla TEM and bla CTX-M genes. Methods: Antibiotic resistance of 51 clinical isolates of K. pneumoniae was determined to amoxicillin, amikacin, ceftazidime, cefotaxime, cefteriaxon, ceftizoxime, gentamicin, ciprofloxacin and nitrofurantoin by disc diffusion. Minimum inhibitory concentrations were also measured for ceftazidime, cefotaxime, cefteriaxon, ceftizoxime and ciprofloxacin. ESBL production was detected by the double disc synergy test and finally, presence of the bla SHV, bla TEM and bla CTX-M genes were shown using specific primers and PCR. Results: Disc diffusion results showed that 96.08 % of the isolates were resistant to amoxicillin followed by 78.43 % resistance to nitrofurantoin, 49.02 % to amikacin and ceftazidime, 41.17 % to ceftriaxone, 37.25% resistance to cefotaxime and ceftizoxime, and 29.42 % to gentamicin and ciprofloxacin. Both resistant and intermediately resistant organisms were resistant in MIC determinations. Twenty two isolates (43.14%) carried bla SHV, 18 (35.29%) had bla TEM and 16 (31.37%) harbored bla CTX-M genes. ESBL production was present in 14 isolates (27.45 %) of which, 3 did not harbor any of the 3 genes. Among the non- ESBL producers, 9 lacked all 3 genes and 2 carried them all. Conclusion: No relation was found between gene presence and ESBL expression

Nonlinear Dynamics in Multimode Optical Fibers

Multimode optical fibers have recently reemerged as a viable platform for addressing a number of long-standing issues associated with information bandwidth requirements and power-handling capabilities. The complex nature of heavily multimoded systems can be effectively exploited to observe altogether novel physical effects arising from spatiotemporal and intermodal linear and nonlinear processes. Here, we have studied nonlinear dynamics in multimode optical fibers (MMFs) in both the normal and anomalous dispersion regimes. In the anomalous dispersion regime, the nonlinearity leads to a formation of spatiotemporal 3-D solitons. Unlike in single-mode fibers, these solitons are not unique and their properties can be modified through the additional degrees of freedom offered by these multimoded settings. In addition, soliton related processes such as soliton fission and dispersive wave generation will be also drastically altered in such multimode systems. Our theoretical work unravels some of the complexities of the underlying dynamics and helps us better understand these effects. The nonlinear dynamics in such multimode systems can be accelerated through a judicious fiber design. A cancelation of Raman self-frequency shifts and Blue-shifting multimode solitons were observed in such settings as a result of an acceleration of intermodal oscillations. Spatiotemporal instabilities in parabolic-index multimode fibers will also be discussed. In the normal dispersion regime, this effect can be exploited to generate an ultrabroad and uniform supercontinuum that extends more than 2.5 octaves. To do so, the unstable spectral regions are pushed away from the pump, thus sweeping the entire spectrum. Multimode parabolic pulses were also predicted and observed in passive normally dispersive tapered MMFs. These setting can obviate the harsh bandwidth limitation present in single-mode system imposed by gain medium and be effectively used for realizing high power multimode fiber lasers. Finally, an instant and efficient second-harmonic generation was observed in the multimode optical fibers. Through a modification of initial conditions, the efficiency of this process could be enhanced to a record high of %6.5

Gender and Feminist Consciousness in Anita Desai’s Novels

This paper critically examines the fictional world of Anita Desai, a prominent Indian woman writer to understand her outlook and standpoint on the socio-cultural issues of female freedom and empowerment. The study finds that Desai while depicting psychological plight of female characters in her novels makes clear that Indian feminism is quite different from the western one. Besides, this paper shows how authentically the writer represents the deplorable status of women in Indian patriarchal society. Keywords: Western Feminism, Indian Feminism, Gender Oppression & Feminist Perspective, Indian Social Milie

Self-synchronization of Kerr-nonlinear Optical Parametric Oscillators

We introduce a new, reduced nonlinear oscillator model governing the spontaneous creation of sharp pulses in a damped, driven, cubic nonlinear Schroedinger equation. The reduced model embodies the fundamental connection between mode synchronization and spatiotemporal pulse formation. We identify attracting solutions corresponding to stable cavity solitons and Turing patterns. Viewed in the optical context, our results explain the recently reported $\pi$ and $\pi/2$ steps in the phase spectrum of microresonator-based optical frequency combs

Teachers’ Pedagogical Belief and its Reflection on the Practice in Teaching Writing in EFL Tertiary Context in Bangladesh.

Writing is the most focused but the least developed English language skill among the learners in Bangladesh. At tertiary level the situation is not different. Surely, alternative approach(es) different from the current practices in teaching writing is/are the timely need to alter the poor standard in English writing of tertiary level students. Cognition or belief related literature suggests what teachers think and believe has a great impact on classroom practices. So, this study investigates teachers’ pedagogical belief in teaching writing assuming it as a vital first step to bring innovations in teaching practices. A mixed-method study was carried out in this regard. 15 teachers from a private university responded to the questionnaire used for this study and two teachers from the same institution were interviewed. The results show a marked discrepancy between teacher belief and practice. Teachers’ lack of orientation in different approaches to teaching writing and contextual constraints are, the study finds out, the major causes behind it. Despite the findings need further extensive research to be validated, the results in this study are definite pointers to the dire necessity of teacher education featuring pedagogical orientation on different approaches to teaching writing, techniques of more student engagement in writing process, ways to increase student motivation in writing and procedures of technology integration and using in teaching writing. Keywords: Teacher belief, Teaching writing, Teacher educatio

Self-synchronization Phenomena in the Lugiato-Lefever Equation

The damped driven nonlinear Schr\"odinger equation (NLSE) has been used to understand a range of physical phenomena in diverse systems. Studying this equation in the context of optical hyper-parametric oscillators in anomalous-dispersion dissipative cavities, where NLSE is usually referred to as the Lugiato-Lefever equation (LLE), we are led to a new, reduced nonlinear oscillator model which uncovers the essence of the spontaneous creation of sharply peaked pulses in optical resonators. We identify attracting solutions for this model which correspond to stable cavity solitons and Turing patterns, and study their degree of stability. The reduced model embodies the fundamental connection between mode synchronization and spatiotemporal pattern formation, and represents a novel class of self-synchronization processes in which coupling between nonlinear oscillators is governed by energy and momentum conservation.Comment: This manuscript is published in Physical Review A. Copyright 2017 by the American Physical Society. arXiv admin note: text overlap with arXiv:1602.0852

Band-edge Bilayer Plasmonic Nanostructure for Surface Enhanced Raman Spectroscopy

Spectroscopic analysis of large biomolecules is critical in a number of applications, including medical diagnostics and label-free biosensing. Recently, it has been shown that Raman spectroscopy of proteins can be used to diagnose some diseases, including a few types of cancer. These experiments have however been performed using traditional Raman spectroscopy and the development of the Surface enhanced Raman spectroscopy (SERS) assays suitable for large biomolecules could lead to a substantial decrease in the amount of specimen necessary for these experiments. We present a new method to achieve high local field enhancement in surface enhanced Raman spectroscopy through the simultaneous adjustment of the lattice plasmons and localized surface plasmon polaritons, in a periodic bilayer nanoantenna array resulting in a high enhancement factor over the sensing area, with relatively high uniformity. The proposed plasmonic nanostructure is comprised of two interacting nanoantenna layers, providing a sharp band-edge lattice plasmon mode and a wide-band localized surface plasmon for the separate enhancement of the pump and emitted Raman signals. We demonstrate the application of the proposed nanostructure for the spectral analysis of large biomolecules by binding a protein (streptavidin) selectively on the hot-spots between the two stacked layers, using a low concentration solution (100 nM) and we successfully acquire its SERS spectrum