249 research outputs found

    Qualitative Methods Can Enrich Quantitative Research on Occupational Stress: An Example From One Occupational Group

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    The chapter examines the ways in which qualitative and quantitative methods support each other in research on occupational stress. Qualitative methods include eliciting from workers unconstrained descriptions of work experiences, careful first-hand observations of the workplace, and participant-observers describing ‘‘from the inside’’ a particular work experience. The chapter shows how qualitative research plays a role in (a) stimulating theory development, (b) generating hypotheses, (c) identifying heretofore researcher-neglected job stressors and coping responses, (d) explaining difficult-to-interpret quantitative findings, and (e) providing rich descriptions of stressful transactions. Extensive examples from research on job stress in teachers are used. The limitations of qualitative research, particularly in the area of verification, are also described

    Qualitative and Quantitative Methods in Occupational-Stress Research

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    The paper examined the ways in which qualitative and quantitative methods support each other in research on occupational stress. Qualitative methods include (a) eliciting from unconstrained descriptions of work experiences, (b) careful first-hand observations at the workplace, and (c) participant‑observers describing “from the inside” a particular work experience. The paper shows how qualitative research stimulates theory development, hypothesis generation, and the identification of job stressors and coping responses. The limitations of qualitative research, particularly in the area of verification, are also described

    Calcite Scale Inhibition: The Case of Mahanagdong Wells

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    ABSTRACT The formation of a calcite scale blockage inside the wellbore of a production well has been one of the problems encountered in Mahanagdong. The presence of a calcite blockage was confirmed in at least six (6) wells, which is mainly attributed to high calcite saturation indices in their fluids. These blockages constrict the flow of geothermal fluids in these wells thus significantly reducing their output. Based on production historical data, decline in field steam availability in Mahanagdong-A sector is mainly attributed to this problem. To meet the steam requirement of the MG-A power plant, output of the wells with calcite blockage should be recovered. Thus, mechanical clearing using a drilling rig was conducted in each of the affected wells to remove the blockage. However, due to cost and risk involved in conducting periodic mechanical clearing, the use of a chemical inhibitor in preventing recurrence of calcite blockage deposition inside the wellbore was considered. To date, a calcite inhibition system was already installed in two (2) of the affected wells in Mahanagdong. The calcite inhibition system basically consists of surface injection facility for the preparation and injection of chemical solution and a downhole injection facility to allow injection of chemical solution inside the wellbore of a producing well below the flash point depth. Based on initial results, decline rate in both wells with installed calcite inhibition system has been reduced significantly from an average of 4.0 kg/s-month to less than 0.5 kg/s-month in terms of total massflow

    Coronary CT Angiography and 5-Year Risk of Myocardial Infarction.

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    BACKGROUND: Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown. METHODS: In an open-label, multicenter, parallel-group trial, we randomly assigned 4146 patients with stable chest pain who had been referred to a cardiology clinic for evaluation to standard care plus CTA (2073 patients) or to standard care alone (2073 patients). Investigations, treatments, and clinical outcomes were assessed over 3 to 7 years of follow-up. The primary end point was death from coronary heart disease or nonfatal myocardial infarction at 5 years. RESULTS: The median duration of follow-up was 4.8 years, which yielded 20,254 patient-years of follow-up. The 5-year rate of the primary end point was lower in the CTA group than in the standard-care group (2.3% [48 patients] vs. 3.9% [81 patients]; hazard ratio, 0.59; 95% confidence interval [CI], 0.41 to 0.84; P=0.004). Although the rates of invasive coronary angiography and coronary revascularization were higher in the CTA group than in the standard-care group in the first few months of follow-up, overall rates were similar at 5 years: invasive coronary angiography was performed in 491 patients in the CTA group and in 502 patients in the standard-care group (hazard ratio, 1.00; 95% CI, 0.88 to 1.13), and coronary revascularization was performed in 279 patients in the CTA group and in 267 in the standard-care group (hazard ratio, 1.07; 95% CI, 0.91 to 1.27). However, more preventive therapies were initiated in patients in the CTA group (odds ratio, 1.40; 95% CI, 1.19 to 1.65), as were more antianginal therapies (odds ratio, 1.27; 95% CI, 1.05 to 1.54). There were no significant between-group differences in the rates of cardiovascular or noncardiovascular deaths or deaths from any cause. CONCLUSIONS: In this trial, the use of CTA in addition to standard care in patients with stable chest pain resulted in a significantly lower rate of death from coronary heart disease or nonfatal myocardial infarction at 5 years than standard care alone, without resulting in a significantly higher rate of coronary angiography or coronary revascularization. (Funded by the Scottish Government Chief Scientist Office and others; SCOT-HEART ClinicalTrials.gov number, NCT01149590 .)

    Non-Standard Errors

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    In statistics, samples are drawn from a population in a data-generating process (DGP). Standard errors measure the uncertainty in estimates of population parameters. In science, evidence is generated to test hypotheses in an evidence-generating process (EGP). We claim that EGP variation across researchers adds uncertainty: Non-standard errors (NSEs). We study NSEs by letting 164 teams test the same hypotheses on the same data. NSEs turn out to be sizable, but smaller for better reproducible or higher rated research. Adding peer-review stages reduces NSEs. We further find that this type of uncertainty is underestimated by participants

    Robust estimation of bacterial cell count from optical density

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    Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data
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