345 research outputs found
Positron annihilation studies of the AlOâ‚“/SiOâ‚‚/Si interface in solar cell structures
Film and film/substrate interfacecharacteristics of 30 and 60 nm-thick AlOₓfilmsgrown on Si substrates by thermal atomic layer deposition(ALD), and 30 nm-thick AlOₓfilms by sputtering, have been probed using variable-energy positron annihilation spectroscopy (VEPAS) and Doppler-broadened spectra ratio curves. All samples were found to have an interface which traps positrons, with annealing increasing this trapping response, regardless of growth method. Thermal ALD creates an AlOₓ/SiOₓ/Si interface with positron trapping and annihilation occurring in the Si side of the SiOₓ/Si boundary. An induced positive charge in the Si next to the interface reduces diffusion into the oxides and increases annihilation in the Si. In this region there is a divacancy-type response (20 ± 2%) before annealing which is increased to 47 ± 2% after annealing.Sputtering seems to not produce samples with this same electrostatic shielding; instead, positron trapping occurs directly in the SiOₓinterface in the as-deposited sample, and the positron response to it increases after annealing as an SiO₂ layer is formed. Annealing the film has the effect of lowering the film oxygen response in all film types. Compared to other structural characterization techniques, VEPAS shows larger sensitivity to differences in film preparation method and between as-deposited and annealed samples.T-T.A.L., S.R., and A.C. acknowledge funding from the
Australian Research Council
AFM imaging reveals the assembly of a P2X receptor complex containing P2X2, P2X4 and P2X6 subunits
Seven P2X purinergic receptor subunits have been identified: P2X1-P2X7. All except P2X6 assemble as homotrimers, and six heteromeric receptors (P2X1/2, P2X1/4, P2X1/5, P2X2/3, P2X2/6 and P2X4/6) have been described. In addition, P2X4 homomers associate with P2X2 or P2X7 homomers as dimers of trimers. The various P2X receptors show individual functional properties, suggesting distinct physiological roles. The overlapping expression of P2X2, P2X4 and P2X6 subunits has been shown in different cell types, and functional analysis of P2X receptors in Leydig cells suggests that the three subunits interact
Dynamic modulation of spatially structured polarization fields for real-time control of ultrafast laser-material interactions
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Atomic force microscopy imaging reveals the formation of ASIC/ENaC cross-clade ion channels
ASIC and ENaC are co-expressed in various cell types, and there is evidence for a close association between them. Here, we used atomic force microscopy (AFM) to determine whether ASIC1a and ENaC subunits are able to form cross-clade hybrid ion channels. ASIC1a and ENaC could be co-isolated from detergent extracts of tsA 201 cells co-expressing the two subunits. Isolated proteins were incubated with antibodies against ENaC and Fab fragments against ASIC1a. AFM imaging revealed proteins that were decorated by both an antibody and a Fab fragment with an angle of ∼120° between them, indicating the formation of ASIC1a/ENaC heterotrimers.J.M.E. and P.J. are supported by Kidney Research U.K. A.P.S. was a member of the University of Cambridge MB/PhD Programme, and was supported by the Jean Shanks Foundation and the James Baird Fund. A research stay of S.H. at Cambridge was supported by a PhD fellowship from the Bayerische Forschungsstiftung
A three arm cluster randomised controlled trial to test the effectiveness and cost-effectiveness of the SMART work & life intervention for reducing daily sitting time in office workers : study protocol
Background:Office-based workers typically spend 70-85% of working hours, and a large proportion of leisure time, sitting. High levels of sitting have been linked to poor health. There is a need for fully powered randomised controlled trials (RCTs) with long-term follow-up to test the effectiveness of interventions to reduce sitting. This paper describes the methodology of a three-arm cluster RCT designed to determine the effectiveness and cost-effectiveness of the SMART Work & Life intervention, delivered with and without a height-adjustable desk, for reducing daily sitting.
Methods/Design:A three-arm cluster RCT of 33 clusters (660 council workers) will be conducted in three areas in England (Leicester; Manchester; Liverpool). Office groups (clusters) will be randomised to the SMART Work & Life intervention delivered with (group 1) or without (group 2) a height-adjustable desk or a control group (group 3). SMART Work & Life includes organisational (e.g., management buy-in, provision/support for standing meetings), environmental (e.g., relocating waste bins, printers), and group/individual (education, action planning, goal setting, addressing barriers, coaching, self-monitoring, social support) level behaviour change strategies, with strategies driven by workplace champions. Baseline, 3, 12 and 24Â month measures will be taken. Objectively measured daily sitting time (activPAL3). objectively measured sitting, standing, stepping, prolonged sitting and moderate-to-vigorous physical activity time and number of steps at work and daily; objectively measured sleep (wrist accelerometry). Adiposity, blood pressure, fasting glucose, glycated haemoglobin, cholesterol (total, HDL, LDL) and triglycerides will be assessed from capillary blood samples. Questionnaires will examine dietary intake, fatigue, musculoskeletal issues, job performance and satisfaction, work engagement, occupational and general fatigue, stress, presenteeism, anxiety and depression and sickness absence (organisational records). Quality of life and resources used (e.g. GP visits, outpatient attendances) will also be assessed. We will conduct a full process evaluation and cost-effectiveness analysis.
Discussion:The results of this RCT will 1) help to understand how effective an important simple, yet relatively expensive environmental change is for reducing sitting, 2) provide evidence on changing behaviour across all waking hours, and 3) provide evidence for policy guidelines around population and workplace health and well-being.
Trial registration: ISRCTN11618007 . Registered on 21 January 2018
Molecular dynamics simulation of the order-disorder phase transition in solid NaNO
We present molecular dynamics simulations of solid NaNO using pair
potentials with the rigid-ion model. The crystal potential surface is
calculated by using an \emph{a priori} method which integrates the \emph{ab
initio} calculations with the Gordon-Kim electron gas theory. This approach is
carefully examined by using different population analysis methods and comparing
the intermolecular interactions resulting from this approach with those from
the \emph{ab initio} Hartree-Fock calculations. Our numerics shows that the
ferroelectric-paraelectric phase transition in solid NaNO is triggered by
rotation of the nitrite ions around the crystallographical c axis, in agreement
with recent X-ray experiments [Gohda \textit{et al.}, Phys. Rev. B \textbf{63},
14101 (2000)]. The crystal-field effects on the nitrite ion are also addressed.
Remarkable internal charge-transfer effect is found.Comment: RevTeX 4.0, 11 figure
Comparison of the Electronic Structures and Energetics of Ferroelectric LiNbO3 and LiTaO3
This paper explains the origin of the ferroelectric instability in LiNbO3 and
LiTaO3 and compares the electronic structures and energetics of the two
materials.Comment: 31 pages, 11 Postscript figure
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