Evaluación técnica y económica del cultivo de caucho (Hevea brasilienses) clon FX 3864 bajo diferentes frecuencias de sangría y Estimulación

Anexo A. ubicación de area de estudio Anexo B. Formato de diagnosticoEste trabajo de investigación tuvo como propósito analizar el desempeño productivo y económico del clon de caucho natural (Hevea brasiliensis Willd. ex Adr. de Juss. Muell. Arg.) FX 3864 en diferentes frecuencias de sangría y con estimulación a base de Ethefon. El experimento se instaló en la Finca del Sr Itilio Durán en el municipio de Belén de los Andaquíes y en la finca La SIRINGA del municipio del El Paujil, departamento del Caquetá. El modelo experimental utilizado fue Diseño completamente al Azar, con cuatro repeticiones o bloques, cada bloque constó de cuatro tratamientos y cada tratamiento de 10 plantas, se aplicó el sistema de sangría 1/2S y dependiendo del tratamiento se le aplicó frecuencias de sangría d/3, d/4 o d/5, los árboles fueron estimulados con Ethefon al 2.5%, el estimulante fue aplicado sobre el sitio del corte sin sernambí. Las variables productivas estudiadas correspondieron a: Producción de látex líquido por sangría, producción de coagulo por sangría, porcentaje de sólidos en una muestra de coagulo húmedo, producción de caucho seco por sangría y contenido de sólidos en el látex de caucho (% DRC). Los datos obtenidos para las variables de Productividad fueron sometidos a análisis de varianza con prueba de comparación de medias de Tukey (P menor que 0.05%), obteniendo como resultado Belén de los Andaquíes como la mejor localidad para todas las variables, el T2: d/4, estimulado con Ethefon al 2.5% como el mejor tratamiento, mientras el menor valor lo presentó el T3: d/5 con estimulación al 2,5% quien evidenció los menores valores para la mayoría de variables exceptuando (DRC). Para el análisis económico de los indicadores de rentabilidad se determinaron los costos de producción por cada tratamiento. Concluido el trabajo se recomienda implementar el T2 (1/2S d/4 6d/7 ET 2,5% 4/y) teniendo en cuenta que presenta la mejor rentabilidad, oscilando entre el 52% y el 58% en las dos localidades

Transportation Needs of Latinos in Pittsfield, MA

Latinos in Pittsfield are a small but fast growing population. The most significant issue they face is related to transportation. Because the area\u27s lack of population density, Berkshire County Regional Transportation Authority provides limited bus routes. In Massachusetts in 2012, 72% of the population drove to work, while in Berkshire County 86% did. Likewise, in Massachusetts, 9% used public transit but in Berkshire County only 2% did. Massachusetts has failed to enact a Safe Driving Bill, even though Sen. Patricia Jehlen and Rep. Tricia Farley-Bouvier have sponsored H.3285

Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. Protective HLA-DRB1*04 subtypes strongly bound the aggregation-prone tau PHF6 sequence, however only when acetylated at a lysine (K311), a common posttranslational modification central to tau aggregation. An HLA-DRB1*04-mediated adaptive immune response decreases PD and AD risks, potentially by acting against tau, offering the possibility of therapeutic avenues

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Faulting evidence of isostatic uplift in the Rincon Mountains metamorphic core complex: An image processing analysis

This study focuses on the applications of remote sensing techniques and digital analysis to characterizing of tectonic features of the Rincon Mountains metamorphic core complex. Data included Landsat Thematic Mapper (TM) images, digital elevation models (DEM), and digital orthophoto quadrangle quads (DOQQ). The main findings in this study are two nearly orthogonal systems of structures that have never been reported in the Rincon Mountains. The first system, a penetrative faulting system of the footwall rocks, trends N10-30°W. Similar structures identified in other metamorphic core complexes. The second system trends N60-70°E, and has only been alluded indirectly in the literature of metamorphic core complexes. The structures pervade mylonites in Tanque Verde Mountain, Mica Mountain, and the Rincon Peak area. As measured on the imagery, spacing between the N10-30°W lineaments ranges from ∼0.5 to 2 km, and from 0.25 to 1 km for the N60-70°E system. Field inspection reveals that the N10-30°W trending system, are high-angle normal faults dipping mainly to the west. One of the main faults, named here the Cabeza de Vaca fault, has a polished, planar, striated and grooved surface with slickenlines indicating pure normal dip-slip movement (N10°W, 83°SW; slickensides rake 85°SW). The Cabeza de Vaca fault is the eastern boundary of a 2 km-wide graben, with displacement as great as 400 meters. The N10-30°W faults are syn- to post-mylonitic, high-angle normal faults that formed during isostatic uplift of the Rincon core complex during mid-Tertiary time. This interpretation is based on previous works, which report similar fault patterns in other metamorphic core complexes. Faults trending N20-30°W, shape the east flank of Mica Mountain. These faults, on the back dipping mylonitic zone, dip east and may represent late-stage antithetic shear zones. The Cabeza de Vaca fault and the back dipping antithetic faults accommodate as much as 65% of the extension due to doming of the core complex. The N60-70°E structures, not verified as a fault system, are a joint system pervading the footwall rocks of the metamorphic core complex. This system is less systematic. Spacing varies from 0.25 to 1 km. Both systems control the drainage of the mountains

Digital analysis applied to mineral exploration at the Puerto Libertad area, Sonora, Mexico

Digital analysis of thematic mapper images and digital elevation model (DEM) of the Puerto Libertad area, emphasized a NE-E structural pattern and a less evident N-S structural trend. These structures may correspond to the distensive mechanisms of the opening of the Gulf of California. Also, semicircular structures in the area were recognized. These are associated to plutonic bodies or local volcanic centers. Exploration targets are most likely to occur in the last type of structures. Analysis included multispectral ratios of bands 5/7 and 5/1 to enhance lithologic discrimination and alteration zones especially hydroxyl-bearing and ferric iron alterations. Principal component analysis to enhance spectral data was also performed. Images revealed new lithologic subdivisions in units previously mapped. Analysis of DEM data and gradient operators from the first principal component image were analyzed to extract textural information

CARACTERIZACIÓN ENTOMOLÓGICA (MARIPOSAS, ESCARABAJOS COPRÓFAGOS Y ABEJAS DE LAS ORQUÍDEAS) EN LA VEREDA PEREGRINOS EN EL MARCO DE LAS EXPEDICIONES CAQUETÁ-BIO

The loss of habitat in Amazonian forests due to deforestation, exerts environmental pressures that alter the physical and ecological conditions of the ecosystems, this causes a decrease in the richness of these insects since they are sensitive to environmental changes. Objective. Know the richness and abundance of euglossine bees, dung beetles and butterflies in the Peregrinos village, Solano-Caquetá. Method. To know the diversity of these groups, samples were taken on three trails, where 20 sampling points were established, at a distance of 50 m each. To collect butterflies, Van Someren Rydon traps were installed as high as possible in search of the canopy, with two baits (decomposing fish and fermented fruit). For the collection of bees, traps for euglossinos were used, which were installed at a height of 5 m., With three attractants (Eucalyptus, Methyl Salicylate, Vanilla), for dung beetles falling traps (Pitffal) were installed that were installed flush from the ground, with human manure. The samplings were carried out in March and April 2021. Results. A total of 3263 individuals were collected, of which 921 individuals of euglossine bees, belonging to 4 genera (Euglossa, Eulaema, Exaerete, Eufriesea) and 22 morphospecies, 1428 individuals of dung beetles, belonging to 9 genera and 14 morphospecies and 914 individuals butterflies belonging to 6 families and 306 morphospecies (255 identified species). Conclusion. The presence of little-known and charismatic species of the Morpho and Agrias genus, in addition to the high richness in the different groups studied, indicates the high degree of conservation, together with their great biological diversity, justifying the design of measures for their preservation and conservation.La pérdida de hábitat en bosques amazónicos a causa de la deforestación, ejerce presiones ambientales que alteran las condiciones físicas y ecológicas de los ecosistemas, esto provoca una disminución en la riqueza de estos insectos ya que son sensibles a los cambios ambientales. Objetivo. Conocer la riqueza y abundancia de abejas euglosinas, escarabajos coprófagos y mariposas en la vereda Peregrinos, Solano-Caquetá. Método. Para conocer la diversidad de estos grupos se realizaron muestreos en tres senderos, donde se establecieron 20 puntos de muestreo, a una distancia de 50 m cada uno. Para recolecta de mariposas se instalaron trampas Van Someren Rydon a la máxima altura posible en busca del dosel, con dos cebos (pescado en descomposición y fruta fermentada). Para la recolecta de abejas se utilizaron trampas para euglossinos, que se instalaron a una altura de 5 m., con tres atrayentes (Eucalipto, Metil Salicilato, Vainilla), para escarabajos coprófagos se instalaron trampas de caída (Pitffal) que fueron instaladas a ras del suelo, con estiércol de humano. Los muestreos se realizaron en marzo y abril de 2021. Resultados. Se recolectaron un total de 3263 individuos, de los cuales 921 individuos de abejas euglossinas, pertenecientes a 4 géneros (Euglossa, Eulaema, Exaerete, Eufriesea) y 22 especies, 1428 individuos de escarabajos coprófagos, pertenecientes a 9 géneros y 16 especies y 914 individuos mariposas pertenecientes a 6 familias y 306 morfoespecies (255 especies identificadas). Conclusión. La presencia de especies poco conocidas y carismáticas de los géneros Morpho y Agrias, además de la alta riqueza en los diferentes grupos estudiados indica el alto grado de conservación, junto con su gran diversidad biológica, que justifican el diseño de medidas para su preservación y conservación

Conectividad en áreas coralinas del Caribe Colombiano : una estrategia de manejo para áreas protegidas

Con el fin de generar información útil para el diseño y la conservación de áreas marinas protegidas, este proyecto evalúa la conectividad entre dos especies de peces (el pargo y la damisela bicolor) residentes en cuatro áreas coralinas representativas del Caribe Colombiano, y que están relacionados con las respectivas estrategias de vida.IP 1118-09-13537Contrato No. 181/2003Sinopsis divulgativa. -- Sinopsis técnica. -- Abstrac. -- Resumen técnico. -- Cuadros de resultados de generación del conocimiento. -- Descripción del impacto actual o potencial de los resultados.;Informe técnico final. [Anexos]: Anexo 1. Análisis genético de Stegastes partitus: un modelo en programas de conservación de áreas marinas en el sur del mar Caribe. [Tesis resumen] / Sandra Patricia Ospina Guerrero. … [et al.]. -- Anexo 2. Análisis genético de Stegastes partitus en poblaciones del Caribe colombiano. [Resumen articulo] / Ricardo G. Landinez M. … [et al]. Anexo 3. Calendario II curso de áreas marinas protegidas / INVEMAR. -- Anexo 4. Nota metodológica: Protocolos. Genotipificación de microsatélites para las especies Lutjanus synagris y Stegastes partitus. PCR-RFLP de los genes mitocondriales Citocromo b y 12S ribosomal en Lutjanus synagris. / Universidad Nacional de Colombia, DIME. -- Anexo 5. Problemática ambiental del sur del mar Caribe (información para cartilla educativa). -- Anexo 6. Taller de manejo de áreas marinas protegidas