4,975 research outputs found
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Valuing the benefit of varicella vaccination: comparison of willingness to pay and quality-adjusted life-years
Vaccination is different from most health interventions because it is preventative, it protects against infectious disease (leading to knock-on effects), the diseases it prevents are usually acute and self-limiting, and most vaccines are given to children from whom it is very difficult to elicit preferences. Because of its unique characteristics, vaccination may possess its own specific attributes. In this paper, we estimate the average Willingness to Pay (WTP) for varicella vaccination and the Quality-Adjusted Life-Years (QALY) lost due to chickenpox using Contingent Valuation (CV), Standard Gamble and Health Utility Index Mark II (HUI2). Furthermore, we identify what attributes of vaccination are important to vaccinees and what elicitation technique can capture these components. To do this, we administered computerised interviews to a sample of parents attending primary Health Centres. Using CV we demonstrate that individuals are willing to pay more for vaccination than treatment. Furthermore, we show that prevention of work loss is an important intervention attribute for parents. On the other hand, consistent with economic theory, the elicitation techniques used to estimate QALYs (Standard Gamble and HUI2) did not capture non-health benefits. Finally, results elicited using the CV were correlated with QALYs measured through the HUI2 questionnaire
Dust obscuration studies along quasar sight lines using simulated galaxies
We use the results of a set of three-dimensional SPH-Treecode simulations
which model the formation and early evolution of disk galaxies, including the
generation of heavy elements by star formation, to investigate the effects of
dust absorption in quasar absorption line systems.
Using a simple prescription for the production of dust, we have compared the
column density, zinc abundance and optical depth properties of our models to
the known properties of Damped Lyman alpha systems.
We find that a significant fraction of our model galaxy disks have a higher
column density than any observed DLA system. We are also able to show that such
parts of the disk tend to be optically thick, implying that any background
quasar would be obscured through much of the disk. This would produce the
selection effect against the denser absorption systems thought to be present in
observations.Comment: 7 pages, 8 figures, to be published in MNRA
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The economics of health
This report presents results from the Economics of Health project funded by the East Midlands Development Agency. The work was undertaken between November 2007 and February 2008. The main aim of the project was to examine the relationship between mental and physical health and employability, labour market participation and economic performance, with specific attention given to the direction of causal relationships
The Chemical Evolution of the Universe I: High Column Density Absorbers
We construct a simple, robust model of the chemical evolution of galaxies
from high to low redshift, and apply it to published observations of damped
Lyman-alpha quasar absorption line systems (DLAs). The elementary model assumes
quiescent star formation and isolated galaxies (no interactions, mergers or gas
flows). We consider the influence of dust and chemical gradients in the
galaxies, and hence explore the selection effects in quasar surveys. We fit
individual DLA systems to predict some observable properties of the absorbing
galaxies, and also indicate the expected redshift behaviour of chemical element
ratios involving nucleosynthetic time delays.
Despite its simplicity, our `monolithic collapse' model gives a good account
of the distribution and evolution of the metallicity and column density of
DLAs, and of the evolution of the global star formation rate and gas density
below redshifts z 3. However, from the comparison of DLA observations with our
model, it is clear that star formation rates at higher redshifts (z>3) are
enhanced. Galaxy interactions and mergers, and gas flows very probably play a
major role.Comment: 36 pages, 11 figures; accepted by MNRA
Long-term Running Experience with the Silicon Micro-strip Tracker at the D{\O} detector
The SiliconMicro-strip Tracker (SMT) at the D{\O} experiment in the Fermilab
Tevatron collider has been operating since 2001. In 2006, an additional layer,
referred to as 'Layer 0', was installed to improve impact parameter resolution
and compensate for detector degradation due to radiation damage to the original
innermost SMT layer. The SMT detector provides valuable tracking and vertexing
information for the experiment. This contribution will highlight aspects of the
long term operation of the SMT, including the impact of the silicon readout
test-stand. Due to the full integration of the test-stand into the D{\O}
trigger framework, this test-stand provides an advantageous tool for training
of new experts and studying subtle effects in the SMT while minimizing impact
on the global data acquisition.Comment: Proceedings of TIPP 2011 (Technology and Instrumentation for Particle
Physics 2011), June 9-14 2011, Chicago, US
Metallicity Evolution in the Early Universe
Observations of the damped Lya systems provide direct measurements on the
chemical enrichment history of neutral gas in the early universe. In this
Letter, we present new measurements for four damped Lya systems at high
redshift. Combining these data with [Fe/H] values culled from the literature,
we investigate the metallicity evolution of the universe from z~1.5-4.5.
Contrary to our expectations and the predictions of essentially every chemical
evolution model, the N(HI)-weighted mean [Fe/H] metallicity exhibits minimal
evolution over this epoch. For the individual systems, we report tentative
evidence for an evolution in the unweighted [Fe/H] mean and the scatter in
[Fe/H] with the higher redshift systems showing lower scatter and lower typical
[Fe/H] values. We also note that no damped Lya system has [Fe/H] < -2.7 dex.
Finally, we discuss the potential impact of small number statistics and dust on
our conclusions and consider the implications of these results on chemical
evolution in the early universe.Comment: 6 pages, 2 encapsulated figures, Latex2e, uses emulateapj.sty and
onecolfloat.sty. Accepted for publication in ApJ Letters: Feb 28, 200
Experimental quantum verification in the presence of temporally correlated noise
Growth in the complexity and capabilities of quantum information hardware
mandates access to practical techniques for performance verification that
function under realistic laboratory conditions. Here we experimentally
characterise the impact of common temporally correlated noise processes on both
randomised benchmarking (RB) and gate-set tomography (GST). We study these
using an analytic toolkit based on a formalism mapping noise to errors for
arbitrary sequences of unitary operations. This analysis highlights the role of
sequence structure in enhancing or suppressing the sensitivity of quantum
verification protocols to either slowly or rapidly varying noise, which we
treat in the limiting cases of quasi-DC miscalibration and white noise power
spectra. We perform experiments with a single trapped Yb ion as a
qubit and inject engineered noise () to probe protocol
performance. Experiments on RB validate predictions that the distribution of
measured fidelities over sequences is described by a gamma distribution varying
between approximately Gaussian for rapidly varying noise, and a broad, highly
skewed distribution for the slowly varying case. Similarly we find a strong
gate set dependence of GST in the presence of correlated errors, leading to
significant deviations between estimated and calculated diamond distances in
the presence of correlated errors. Numerical simulations demonstrate
that expansion of the gate set to include negative rotations can suppress these
discrepancies and increase reported diamond distances by orders of magnitude
for the same error processes. Similar effects do not occur for correlated
or errors or rapidly varying noise processes,
highlighting the critical interplay of selected gate set and the gauge
optimisation process on the meaning of the reported diamond norm in correlated
noise environments.Comment: Expanded and updated analysis of GST, including detailed examination
of the role of gauge optimization in GST. Full GST data sets and
supplementary information available on request from the authors. Related
results available from
http://www.physics.usyd.edu.au/~mbiercuk/Publications.htm
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