Locating Aquifers in Crystalline Granitic Rock Using Electrical Resistivity Technique in the Sissala East District of Ghana

Groundwater prospecting in the Sissala East District has been conducted using the electrical resistivity method.  This has been done with the objective of locating suitable sites for borehole drilling and to determine groundwater potential of the district. The dipole-dipole technique of the electrical resistivity method was conducted using the McOhm 2119 resistivity meter in the horizontal profiling (HP) and vertical electrical sounding (VES) modes simultaneously. Geophysical data taken in both the HP and VES modes were presented in two dimensional (2-D) coloured vertical cross sections, from which VES curves were also plotted for selected station points and interpreted qualitatively. Results of the 2-D vertical cross sections and VES curves predicted an average depth range of groundwater or moisture interception of 10 to 15 m. The apparent resistivity of the wet boreholes was in the range of 15 Ωm and 300 Ωm. These were quantitatively confirmed with drill logs of the wet boreholes. The drill logs further showed that main aquifers and fractures were encountered between 20 m and 50 m depth range. The results yielded a success rate of about 89 %, thereby indicating that the district has a great potential for groundwater to meet their domestic and irrigation needs. Therefore, the dipole-dipole technique is effective in locating aquifers for groundwater in crystalline granitic rocks. Keywords: Groundwater, Crystalline granitic rock, Aquifers, Apparent Resistivit

SPATIAL ANALYSIS OF LAND DISPUTES IN THE ASHANTI REGION

Context and Background: Land is an important resource for human survival as well as that of other living organisms. Despite its importance, there are many problems that come with its management. There are increasing controversies and disputes over the ownership, access, and use of land. This is due to the increase in land demand, owing to factors such as population growth, urbanization, and food security. Land disputes in the Ashanti Region have drastically escalated recently as a result of these factors. Many land parcels have been left underdeveloped as a result of these disputes.Goal and Objectives:This study investigates land dispute cases from 2016 to 2021 in the Ashanti Region using survey records of land dispute cases from the Ashanti Regional Lands Commission.Methodology:The study reviewed 203 land dispute case files from the Lands Commission to perform spatial analysis in identifying the hotspot zones of land disputes in the area of study. Ripley’s K-function was used to test the null hypothesis of complete spatial randomisation and Moran’s I was used to measure the spatial autocorrelation of the land dispute incidences. A kernel density map was used to show the intensity of recorded disputes in the hotspot zones.Results:It was evident from the study that most of the land dispute cases were recorded in and around the central part of the study area. A map depicting the spatial extent and hotspot zones of the land dispute cases was developed to provide contextual background for policy makers, and researchers. Based on the Moran Scatterplots, Local Indicators of Spatial Association (LISA) cluster maps were used to identify hotspot zones in the study area. A total of 12 localities were identified as hotspot zones in the study area. The incidence of land disputes was mostly in the peri-urban areas with proximity to the Central Business District. Further research is recommended to probe into factors that influence a locality or town’s vulnerability to land

Effect of Winter Canola Cultivar on Seed Yield, Oil, and Protein Content

Canola (Brassica napus L.) is an oilseed crop that can produce healthy cooking oil and animal feed byproducts. Although it is a relatively new crop, approved for human consumption less than 40 yr ago, advances in breeding have allowed for its production as a winter crop in the southeastern United States. There is little published research, however, related to its performance and quality in this region. Therefore, a study was conducted during the 2014–2015 (Year 1) and 2015–2016 (Year 2) seasons in Tennessee. Twenty-three varieties were planted in a randomized complete block design with four replications across both years to determine seed yield, seed oil, and seed protein content. Differences in fertilizer application rates, planting, and harvest management and differences in weather conditions probably led to significant interactions between years. Cultivar yields ranged from 1269 to 2647 and 1494 to 4199 kg ha−1, seed oil content ranged from 44 to 48% and from 43 to 46%, and seed protein content ranged from 20 to 24% and from 19 to 23% for Years 1 and 2, respectively. In each year, open-pollinated cultivars had significantly lower yield and oil content but significantly greater protein content than hybrid cultivars. There was also a strong negative correlation between seed oil and seed protein and the linear models were significant (r = 0.88, p \u3c 0.0001 for Year 1; r = 0.85, p \u3c 0.0001 for Year 2). Recommended winter canola cultivars include Exp1302 and Hekip

Knowledge of HIV/AIDS among older adults (50 years and above) in a peri-urban setting: A descriptive cross-sectional study

Background: In the absence of vaccine or cure, public knowledge about Human Immune Virus (HIV) is a central tool for curbing HIV epidemic. This study sought to assess the knowledge of HIV among older adults (50 years and above) at the Methodist Faith Healing hospital, Ankaase, Ghana. Methods: Using a descriptive study design, older adults (50 years and above) who visited the Ankaase Methodist Faith Healing hospital were randomly sampled for the study. A structured questionnaire was administered to collect data which was analyzed quantitatively using Statistical Package for Social Sciences (SPSS version 16.0). Results: A total of 100 respondents who were aged 50 to 68 (54 ± 2.3) were recruited. Most of the respondents had average knowledge of the mode of HIV transmission (62%) as well as HIV prevention (58%) and signs and symptoms of HIV (60%). HIV status was significantly associated with HIV knowledge among older adults as HIV positive respondents were 2.25 times more knowledgeable in terms of signs and symptoms, mode of transmission and prevention of HIV [AOR (95% CI) 2.25(1.02-8.68)]. Conclusion: Most older adults (50 years and above) have average knowledge of the mode of transmission, prevention as well as signs and symptoms of HIV. The National Commission for Civic Education should collaborate with various key stakeholders to educate older adults on issues related to HIV/AIDS

Stage at diagnosis of breast cancer in sub-Saharan Africa: a systematic review and meta-analysis

Background The incidence of breast cancer in sub-Saharan Africa is relatively low, but as survival from the disease in the region is poor, mortality rates are as high as in high-income countries. Stage at diagnosis is a major contributing factor to poor survival from breast cancer. We aimed to do a systematic review and meta-analysis on stage at diagnosis of breast cancer in sub-Saharan Africa to examine trends over time, and investigate sources of variations across the region. Methods We searched MEDLINE, Embase, Web of Knowledge, and Africa-Wide Information to identify studies on breast cancer stage at diagnosis in sub-Saharan African women published before Jan 1, 2014, and in any language. Random-effects meta-analyses were done to investigate between-study heterogeneity in percentage of late-stage breast cancer (stage III/IV), and meta-regression analyses to identify potential sources of variation. Percentages of women with late-stage breast cancer at diagnosis in sub-Saharan Africa were compared with similar estimates for black and white women in the USA from the Surveillance, Epidemiology, and End Results database. Findings 83 studies were included, which consisted of 26 788 women from 17 sub-Saharan African countries. There was wide between-study heterogeneity in the percentage of late-stage disease at diagnosis (median 74·7%, range 30·3–100%, I2=93·3%, p<0·0001). The percentage of patients with late-stage disease at diagnosis did not vary by region in black women, but was lower in non-black women from southern Africa than in black women in any region (absolute difference [AD] from black women in western Africa [reference group] −18·1%, 95% CI −28·2 to −8·0), and higher for populations from mixed (urban and rural) settings rather than urban settings (13·2%, 5·7 to 20·7, in analyses restricted to black women). The percentage of patients with late-stage disease at diagnosis in black Africans decreased over time (–10·5%, −19·3 to −1·6; for 2000 or later vs 1980 or before), but it was still higher around 2010 than it was in white and black women in the USA 40 years previously. Interpretation Strategies for early diagnosis of breast cancer should be regarded as a major priority by cancer control programmes in sub-Saharan Africa

Differences in Seed Yield, Meal and Oil Quality by Winter Canola Variety and Planting Date in Tennessee

Canola (Brassica napus L.) is a cool season crop from the mustard (Brassicaceae) family developed in the 1970s, which contains about 40% oil. This research was carried out to determine the differences in yield and qualities of some winter canola varieties during two growing seasons (2014-2015 and 2015-2016) in Ashland City, Tennessee. In this research, randomized complete block design (RCBD) was used with four replicate in the two growing seasons. Seed yield, oil content and protein content were significantly different between the common cultivars when both years were combined. Exp 1302 (3423 kg ha-1) was greatest in terms of seed yield across both years while Einstein (44.32%) and Sumner (380 g kg-1) were the greatest for oil and protein content, respectively. For seed yield, Exp1302, Hekip, Einstein, Hornet, Edimax CL, DK Imistar CL, Claremore and DK Sensei had greater average values than other varieties across both years. For oil content, Einstein, Mercedes, PX112, Exp1302, MH11J41 and Popular had the greatest concentrations across years. Finally, for meal protein content, Sumner, Wichita, Claremore, Virginia and VSX-3 had high average concentrations across years. Exp1302 and Einstein may be the best cultivars to grow in Tennessee if oil content is more important than meal protein content while Claremore may be the best cultivar to grow in Tennessee if meal protein content is more important than oil content. None of these, however, are currently commercially available in the U.S. Since yield is the greatest factor for revenue, Hekip, Hornet, and Edimax CL are the recommended varieties for growers in Tennessee

A test of behavioural changes to electronic levy: Evidence from mobile money transactions in a developing country

AbstractEven before its introduction, the electronic levy in Ghana stirred up different behavioural reactions from the public, despite the intention to use its proceeds to provide better public services. As a result, this study examines some of these behavioural changes using pre-tax survey data on the proposed electronic levy. Using a sample size of 2,810 individuals with mobile money accounts, we estimate a multivariate logit model with its marginal effects to determine the associated drivers of individuals’ behavioural changes to the proposed tax. The results show that the electronic levy is likely to have an immediate impact on an individual’s behaviour in positive and negative ways. Thus, while about 88% of the respondents indicated that they are likely to stop using mobile money or reduce their transactions, approximately 12% of the respondents rather reaffirmed their willingness to keep using mobile money or perhaps increase their mobile-money transactions. Furthermore, we find evidence that income, marital status, objective knowledge, trust in government, and the implementation timeframe are the statistically significant determinants of behavioural changes to the electronic tax in Ghana. The results suggest varying behavioural responses to the electronic levy in Ghana, which threaten the realization of expected revenues. We recommend proper education and advocacy at all levels and a keen consideration to implement the levy later, perhaps, when there is more trust in the government’s ability to use tax revenues prudently

Pre-Exposure Prophylaxis for HIV Prevention : Safety Concerns

Available evidence supports the efficacy of pre-exposure prophylaxis (PrEP) in decreasing the incidence of human immunodeficiency virus (HIV) infection among high-risk individuals, especially when used in combination with other behavioural preventive methods. Safety concerns about PrEP present challenges in the implementation and use of PrEP. The aim of this review is to discuss safety concerns observed in completed clinical trials on the use of PrEP. We performed a literature search on PrEP in PubMed, global advocacy for HIV prevention (Aids Vaccine Advocacy Coalition) database, clinical trials registry " http://www.clinicaltrials.gov " and scholar.google, using combination search terms 'pre-exposure prophylaxis', 'safety concerns in the use of pre-exposure prophylaxis', 'truvada use as PrEP', 'guidelines for PrEP use', 'HIV pre-exposure prophylaxis' and 'tenofovir' to identify clinical trials and literature on PrEP. We present findings associated with safety issues on the use of PrEP based on a review of 11 clinical trials on PrEP with results on safety and efficacy as at April 2016. We also reviewed findings from routine real-life practice reports. The pharmacological intervention for PrEP was tenofovir disoproxil fumarate/emtricitabine in a combined form as Truvada®or tenofovir as a single entity. Both products are efficacious for PrEP and seem to have a good safety profile. Regular monitoring is recommended to prevent long-term toxic effects. The main adverse effects observed with PrEP are gastrointestinal related; basically mild to moderate nausea, vomiting and diarrhea. Other adverse drug effects worth monitoring are liver enzymes, renal function and bone mineral density. PrEP as an intervention to reduce HIV transmission appears to have a safe benefit-risk profile in clinical trials. It is recommended for widespread use but adherence monitoring and real-world safety surveillance are critical in the post-marketing phase to ensure that the benefits observed in clinical trials are maintained in real-world use

Association Between the Occurrence of Adverse Drug Events and Modification of First-Line Highly Active Antiretroviral Therapy in Ghanaian HIV Patients

INTRODUCTION: Patients initiated on highly active antiretroviral therapy (HAART) generally remain on medication indefinitely. A modification in the HAART regimen may become necessary because of possible acute or chronic toxicities, concomitant clinical conditions, development of virological failure or the advent of adverse drug events. The study documents adverse drug events of HIV-positive Ghanaian patients with HAART modifications. It also investigates the association between documented adverse drug events and HAART modification using an unmatched case-control study design. METHOD: The study was conducted in the Fevers Unit of the Korle Bu Teaching Hospital and involved patients who attended the HIV Care Clinic between January 2004 and December 2009. Data from 298 modified therapy patients (cases) were compared with 298 continuing therapy patients (controls) who had been on treatment for at least 1 month before the end of study. Controls were sampled from the same database of a cohort of HIV-positive patients on HAART, at the time a case occurred, in terms of treatment initiation ±1 month. Data were obtained from patients' clinical folders and the HIV clinic database linked to the pharmacy database. The nature of the documented adverse drug events of the cases was described and the association between the documented adverse drug events and HAART modification was determined by logistic regression with reported odds ratios (ORs) and their 95 % confidence interval (CI). RESULTS: Among the 298 modified therapy patients sampled in this study, 52.7 % of them had at least one documented adverse drug event. The most documented adverse drug event was anaemia, recorded in 18.5 % of modified therapy patients, all of whom were on a zidovudine-based regimen. The presence of documented adverse drug events was significantly associated with HAART modification [adjusted OR = 2.71 (95 % CI 2.11-3.48), p < 0.001]. CONCLUSION: Among HIV patients on HAART, adverse drug events play a major role in treatment modification. Occurrence of adverse drug events may be used as a predictor for possible therapy modification. We recommend the institution of active pharmacovigilance in HIV treatment programmes as it permits the proper identification and characterisation of drug-related adverse events. This can help develop approaches towards their management and also justify therapy modifications