International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS

Parenthood in pediatric liver transplant patients

PubMed ID: 22404458Liver transplantation has become a universally accepted treatment for numerous congenital and acquired hepatic disorders that cause liver failure. Without liver transplantation, patients in their reproductive years are afflicted with oligospermia or azoospermia in men and amenorrhea in women, with infertility being a consequence in both sexes. The aim of this study is to describe our experiences concerning the parenthood of pediatric individuals who are successful recipients of liver transplantations coming into the reproductive years of life. We retrospectively analyzed data of 207 pediatric liver transplanted patients (96 women, 111 men). Among them, three women conceived and delivered four babies, and two men admitted to paternity of two children after they all had been recipients of liver transplants. All female transplant recipients had received tacrolimus-based immunosuppression. Preterm delivery was the most clinically important complication among these patients. Only one of the female patients experienced hypercalcemia during the pregnancy. None had any other complications such as hypertension, preeclampsia, cholestasis, or diabetes. There was no graft insufficiency, rejection, or birth defect. We concluded that maternity and paternity in liver transplant patients show normal outcomes even though this procedure occurs in childhood, and pregnancy did not seem to impair graft function in patients receiving immunosuppressive drugs. © 2012 John Wiley & Sons A/S

Detection of infection preferences of the alfalfa seed chalcid, bruchophagus roddi gussakovskiy, 1933 (Hymenoptera: Eurytomidae) in alfalfa (medicago sativa l.) fields of igdir, Turkey

This study was conducted to estimate the infection of Bruchophagus roddi in 66 alfalfa fields in Igdir, Turkey during the month of August in 2014-2015, and to determine infection preferences of B. roddi for number of pods in a bunch (NPB) and number of seeds in a pod (NSP). CHAID algorithm was preferred in the prediction of the number of seeds damaged (NSD) through district, year, NPB and NSP. In Aralik district, B. roddi preferred the seeds of varieties with NSP?3.8 (0.858 NSD) at lower rate in 2015. In Karakoyunlu, Tuzluca and Central districts in 2015, varieties with NPB>11 were preferred less but varieties with 910 were preferred less but varieties whose NSP was greater than 7.6 were preferred at the highest proportion by B. roddi in Aralik district in the 2015. © 2018, Agricultural Research Communication Centre. All rights reserved

CYCLOSPORINE TREATMENT FOR SEVERE STEROID RESISTANT ULCERATIVE COLITIS IN CHILDREN

WOS: 00027855010022