A Case of Acrokeratosis Verruciformis Treated with Acitretin

Acrokeratosis Verruciformis is a rare autosomal dominant genodermatosis. Typically, the lesions are small, verrucous, flat papules on the dorsal aspects of the hands and feet, elbows and knees. Herein, we report a sporodic case of acrokeratosis verruciformis, succesfully treated with acitretin, and review of the literatures

Assessment the effect of diabetes education on self-care behaviors and glycemic control in the Turkey Nursing Diabetes Education Evaluating Project (TURNUDEP): a multi-center study

Background: Diabetes education in Turkey is provided by diabetes nurse educators in almost all healthcare organizations. However, the education is not standardized in terms of learning content, duration, and methods. This multi-center study was performed to assess the self-care behaviors and glycemic control following education provided to the patients with type 2 diabetes mellitus by diabetes nurse educators. Methods: This was a descriptive and cross-sectional study and included 1535 patients admitted to 28 public hospitals for the treatment of type 2 diabetes mellitus. The education was assessed by using a Patient Identification Form and Self-care Scale. Results: The proportion of individuals who received diabetes education within the last year was 78.5%, with 46.7% of them having received it once. Of the patients, 84.8% reported that they received diabetes education individually. It was found that the proportion of individuals who received education about oral antidiabetics (78.5%) and glucose testing at home (78.5%) was higher than the proportion of individuals who received education about exercise (58.8%) and foot care (61.6%). The status of diabetes education, education intervals, and the correlation of the education method with self-care and glycemic control was evaluated. Self-care and glycemic control levels were better among the patients who received diabetes education thrice or more and in patients who received education both individually and in a group (p < 0.05). Conclusions: Approximately three-quarters of individuals with type 2 diabetes mellitus received education by diabetes nurse educators in Turkey. Diabetes education is positively correlated with self-care and glycemic control levels among patients with type 2 diabetes mellitus. Efforts for generalization and standardized education for all diabetes patients are necessary. © 2022, The Author(s)

Efficacy of Er:YAG Laser in Scaling and Root Planing and Use of i-PRF as a Biomodifier: An In Vitro Study

Periodontitis produces significant changes in the tooth, called the root surface, which are pathologically exposed. The etiology of periodontitis is bacteria that adhere to the root surface and thrive in a biofilm environment. One of the goals of periodontal therapy is to regenerate the lost periodontium and transform the root surface into a biologically favorable substrate for epithelial and connective tissue cell adhesion. Mechanical therapy for debridement of root surfaces affected by periodontitis focuses on removing the etiologic agents of periodontal disease and allowing attachment of periodontal tissues to restore biocompatibility. Mechanical debridement of root surface deposits is currently considered the gold standard treatment for these diseases. Considering the specific properties of the laser, such as hemostatic effects, selective calculus ablation or bactericidal activity, an appropriate laser application may provide an alternative to mechanical or amplified root debridement. Root biomodification refers to procedures performed to detoxify, decontaminate and demineralize the root surface to remove the smear layer and expose the collagen matrix of dentin and cementum. Autogenous platelet-derived products obtained from the patient's own blood have been used frequently in regenerative applications in recent years, and positive results have been obtained both clinically and histologically. For this purpose, the healing-enhancing effects of i-PRF, which has the capacity to be a biomodifier on root surfaces, on the attachment of gingival fibroblasts and wound healing are worth examining. Materials and Method A total of 36 previously extracted human teeth will be used in our study. These samples will be divided into 4 groups (n=9). The procedures to be performed on the groups, respectively, are scaling and root planning with mechanical treatment, scaling and root planning with Er:YAG laser, mechanical treatment + i-PRF application, and Er:YAG laser + i-PRF application. Prior to the procedure, the teeth will be cleaned with distilled water and stored in phosphate buffered saline (PBS) at 4 °C until the treatments are done. After the procedures applied to the teeth, samples will be obtained with the help of 4 mm diameter trepan burs. Obtained samples will be examined under scanning electron microscopy in order to compare the criteria of dentin demineralization, presence/absence of thermal damage, width of dentinal tubule diameters and presence/absence of smear layer

Cigarette smoking and periodontal disease

Periodontai hastalıkların başlamasında ve ilerlemesinde plak ve konak savunma sistemine ilaveten bazı lokal ve sistemik risk faktörlerinin etkili olduğu bilinmektedir. Son dönemlerde içeriğinde bazı zararlı ve kanserojen maddeler bulunduran sigara da periodontal hastalıklarda çevresel risk faktörü olarak kabul edilmektedir. Sigaranın periodontai sağlık üzerine zararlı etkilerini hangi mekanizma veya mekanizmalar ile gerçekleştirdiği ise tam olarak bilinmemektedir. Bu derlemedeki veriler, periodontai durum üzerine sigara kullanımının etkilerini değerlendirmede yardımcı olacaktır.It's known that there are some local and systemic risk factors in the onset and progression of periodontal diseases as well as dental plaque and host defense mechanism. Recently, cigarette that includes some detrimental and carcinogen materials, has also been found as an environmental risk factor. However, it's not well-known that cigarette smoking forms the detrimental effects on periodontai health by which mechanism or mechanisms. Data regarding the impact of smoking on periodontai status included in this review will be helpful

Relationship between smoking and folic acid, vitamin B-12 and some haematological variables in patients with chronic periodontal disease

WOS: 000242441600004PubMed: 17092240Aim: The purpose of this study was to investigate the relationship between cigarette smoking and the serum levels of folic acid, vitamin B-12 and some haematological variables in patients with periodontal disease. Patients and methods: The study base consisted of 88 volunteer patients with periodontal disease, including 45 current smokers in the age range 31-68 years and 43 non-smokers in the range 32-66 years. The clinical parameters included plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD) and clinical attachment loss (CAL). Folic acid, vitamin B-12 and haematological variables were determined from peripheral blood samples. Results: PI, PD and CAL means were significantly higher in smokers than nonsmokers (p < 0.05). The serum folic acid concentration of smokers was lower than that of non-smokers (p < 0.05), whereas the white blood cell count was higher in smokers than in non-smokers (p < 0.05). Conclusion: The results of this study suggest that among patients with periodontal disease the serum folic acid concentration is lower in smokers compared with non-smokers

The detection of salivary minerals in smokers and non-smokers with chronic periodontitis by the inductively coupled plasma-atomic emission spectrophotometry technique

Erdemir, Ali/0000-0002-6489-9620; Erdemir, Ali/0000-0003-1140-3887WOS: 000241879100009PubMed: 16734573Background: The purpose of this study was to evaluate the effect of smoking on the salivary minerals in subjects with chronic periodontitis by the inductively coupled plasma-atomic emission spectrophotometry (ICP-AES) technique. Methods: The study group included 24 subjects - 12 smokers and 12 non-smokers-with chronic periodontitis. Clinical measurements and non-stimulated whole saliva were obtained, and the levels of five elements-sodium, potassium, calcium, magnesium, and phosphate-in each specimen were analyzed. Results: When the clinical parameters were compared between groups, only plaque index was significantly higher in smokers than non-smokers (P < 0.05). The mean plaque index of smokers and non-smokers was 1.93 +/- 0.51 and 1.51 +/- 0.39, respectively. The results of this study showed that there were no significant differences between groups in the mineral content of saliva. In smokers, there were positive correlations between the levels of calcium, sodium, and magnesium and clinical attachment level. There was also a positive correlation between the level of phosphate and the percentage of bleeding on probing. In non-smokers, there was a negative correlation only between the mean level of sodium and plaque index (P < 0.05). Conclusions: The present study showed that no significant differences were found between the mineral content of saliva of smokers and non-smokers by the ICP-AES technique. It is a useful, fast, and sensitive technique compared to other techniques, and it can be advised for researchers while analyzing the mineral content of saliva

A retrospective analysis of 15 patients with cutaneous sarcoidosıs Kutanöz sarkoidozlu 15 hastanın geriye dönük analizi

Objective: Sarcoidosis is a multisystemic disease characterized by non-caseating granuloma of unknown origin. The purpose of our investigation was to review our patients with cutaneous sarcoidosis in order to evaluate their clinicopathological features and the relationship of cutaneous sarcoidosis with systemic sarcoidosis. Materials and Methods: The medical records of 15 patients diagnosed with cutaneous sarcoidosis at Erciyes University, Dermatology Department between 2005 and 2010 were retrospectively reviewed. Results: Twelve patients were women, 3 patients were men. The most common presentation of cutaneous sarcoidal lesions was the nodulo-plaque form (66.6%) and the most common localization of the lesions were the head-and-neck and the lower extremities in six each (40%, each one). Although all of the patients' primary complaints were cutaneous symptoms, pulmonary involvement was noticed in 6 patients (40%) with cutaneous sarcoidosis. Conclusion: The data of the study suggest that cutaneous sarcoidosis mainly occurs at the onset of the systemic disease. Hence, all patients presenting to the dermatology departments with cutaneous sarcoidal granulomas require investigations for systemic sarcoidosis