Effect of Monosodium Glutamate on the Digestibility of Different Nutrients Using Standardized Static In vitro Digestion Model

Monosodium glutamate (MSG) is a flavor enhancer and food additive with a unique umami taste. Due to its widespread use in humans, this study focused on the cytotoxicity, anti-diabetic effect, and interaction with protein digestion by performing a standardized static in vitro digestion model and lipid digestion by estimating free fatty acids released from 0.5 g of olive oil during intestinal lipolysis. The study showed that monosodium glutamate has an apparent cytotoxic effect on the Caco-2 cell line in a dose-dependent manner. MSG glutamate also showed low inhibitory activity on alpha-glucosidase enzyme even at high concentrations (16.3 % at 1800 ppm). By performing simulated in vitro digestion to study the interaction between MSG and protein digestion, followed by MTT study, total protein determination, and pH drop method, all results concluded that MSG affected proteolysis. Finally, the impact of MSG on lipolysis was studied through a free fatty acid release test. The results of the study demonstrated that MSG harmed fat digestibility in a concentration-dependent manner. As a result, it is essential to conduct further studies, especially in vivo studies, to determine the potential negative effects of MSG on human health

Dewetting and transport property enhancement: antimonide crystals for high performance electronic device

International audienceThe dewetting technique has been applied to the growth of InSb and GaSb polycrystals. After optimization of the set up and growth parameters, four samples, 88 mm in length and 11 mm in diameter, have been obtained. Their electrical properties were investigated in relation to the type of solidification (attached, dewetted and so on). In spite of the polycrystalline structure of these samples, room temperature Hall mobilities obtained for dewetted antimonide samples have shown the highest values obtained till now. These results indicate that dewetting can be used to produce InSb and GaSb with high mobility for device applications

Synthesis and Characterization of LaCu0.25Mn0.75O3-δ Nanoparticles Perovskite Materials

A spongy black powder of LaCu0.25Mn0.75O3-δ was synthesized by a modified Pechini method in this study. Properties of LaCu0.25Mn0.75O3-δ perovskite were investigated via in situ Fourier transform infrared (FTIR) spectroscopy. X-ray diffraction results indicated obtaining highly crystalline LaCu0.25Mn0.75O3-δ sample with crystallite size was 37 nm. FTIR results confirmed the formation of LaCu0.25Mn0.75O3-δnanoparticles. High-Resolution Transmission Electronic Microscope HRTEM image illustrates that the prepared sample is in the nanoscale with d-spacing equal to 0.13 nm matching the [440] plane of cubic LaCu0.25Mn0.75O3-δ.The optical properties of the obtained samples were investigated and indicated that the prepared sample is in the nanoscale