69 research outputs found

    Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry

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    Gastrointestinal symptoms and association with medication use patterns, adherence, treatment satisfaction, quality of life, and resource use in osteoporosis: baseline results of the MUSIC-OS study

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    Summary: The Medication Use Patterns, Treatment Satisfaction, and Inadequate Control of Osteoporosis Study (MUSIC-OS) is a prospective, observational study of women with osteoporosis in Europe and Canada. At baseline, patients with gastrointestinal symptoms reported lower adherence to osteoporosis treatment, treatment satisfaction, and health-related quality of life, than those without gastrointestinal symptoms. Introduction: The aim of the study was to examine gastrointestinal (GI) symptoms and the association between GI symptoms and treatment adherence, treatment satisfaction, and health-related quality of life (HRQoL) among osteoporotic women in Europe and Canada. Methods: Baseline results are reported here for a prospective study which enrolled postmenopausal, osteoporotic women who were initiating (new users) or continuing (experienced users) osteoporosis treatment at study entry (baseline). A patient survey was administered at baseline and included the occurrence of GI symptoms during 6-month pre-enrolment, treatment adherence (adherence evaluation of osteoporosis (ADEOS), score 0–22), treatment satisfaction (Osteoporosis Treatment Satisfaction Questionnaire for Medications (OPSAT-Q), score 0–100) and HRQoL (EuroQol-5 dimension (EQ-5D) utility, score 0–1; OPAQ-SV, score 0–100). The association between GI symptoms and ADEOS (experienced users), OPSAT-Q (experienced users), and HRQoL (new and experienced users) was assessed by general linear models adjusted for patient characteristics. Results: A total of 2959 patients (2275 experienced and 684 new users) were included. Overall, 68.1 % of patients experienced GI symptoms in the past 6 months. Compared with patients without GI symptoms, patients with GI symptoms had lower mean baseline scores on most measures. The mean adjusted differences were ADEOS, −0.43; OPSAT-Q, −5.68; EQ-5D, −0.04 (new users) and −0.06 (experienced users), all P < 0.01. GI symptoms were also associated with lower OPAQ-SV domain scores: physical function, −4.17 (experienced users); emotional status, −4.28 (new users) and −5.68 (experienced users); back pain, −5.82 (new users) and −11.33 (experienced users), all P < 0.01. Conclusions: Patients with GI symptoms have lower treatment adherence and treatment satisfaction and worse HRQoL than patients without GI symptoms

    Caves in Myanmar

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    Due to long-standing travel restrictions, the karst and caves have not been widely investigated in Myanmar (the country once known as Burma). Access is now easier to some parts of the country, though others remain virtually closed to foreigners. A useful overview of Myanmar caves was presented by Dunkley et al. (1989). More has been revealed since the Harrison Institute (based in England) has pursued its biodiversity research into the bats that occupy a critical site between the Indian sub-continent and the peninsulas of Southeast Asia

    15th Internationanternational Congress of Speleology: Are you Ready to Register?!

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    The International Congress of Speleology (ICS) is the world’s premier speleological event. An event of the International Union of Speleology (UIS), it is held once every four years in a location selected by the delegates of the UIS member nations. The next ICS will be held in Kerrville, Texas, USA on 19-26 July 2009

    Caves in Myanmar

    No full text
    Due to long-standing travel restrictions, the karst and caves have not been widely investigated in Myanmar (the country once known as Burma). Access is now easier to some parts of the country, though others remain virtually closed to foreigners. A useful overview of Myanmar caves was presented by Dunkley et al. (1989). More has been revealed since the Harrison Institute (based in England) has pursued its biodiversity research into the bats that occupy a critical site between the Indian sub-continent and the peninsulas of Southeast Asia
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