The Victorian Newsletter (Fall 1978)

The Victorian Newsletter is sponsored for the Victorian Group of the Modern Language Association by the University of Florida and is published twice annually.Ironic Translation in Fifine at the Fair / Dorothy Mermin -- The Heroine of Middlemarch / Gordon S. Haight -- How Many Children had Barry Lyndon? / Winslow Rogers -- Martin Chuzzlewit: The Art of the Critical Imagination / David D. Marcus -- A New Carlyle Manuscript / Roger L. Tarr -- Disraeli's Sybil and Hollinshed's Chronicles / Lois E. Bueler -- Thackeray in Elizabeth Gaskell's The Life of Charlotte Brontë: Some Manuscript & Evidence / Angus Easson -- Dickens with a Voice like Burke's / Louie Crew -- In Defense of Margaret: Another Look at Arnold's "The Forsaken Merman" / Frank R. Giordano, Jr. -- Yeats, Tennyson, and "Innisfree" / Gary Sloan -- Victorian Group New

Mary Barton

xxxvii, 390 p.; 21 cm

The life of Charlotte Brontë

xxxvi, 587 p. ; 19 cm

Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists

Novel 3-(1H-indol-3-yl)-1,2,4-oxadiazoles and -thiadiazoles were synthesized and found to be potent CB1 cannabinoid receptor agonists. The oral bioavailability of these compounds could be dramatically improved by optimization studies of the side chains attached to the indole and oxadiazole cores, leading to identification of a CB1 receptor agonist with good oral activity in a range of preclinical models of antinociception and antihyperalgesia

Chronology and Statistics : Objective Understanding of Authorial Meaning

This paper is an attempt to prove that chronology and statistics are the effective means for objective interpretation of authorial meaning. In defence of his hermeneutic theory against Eagleton’s liberal-humanistic opposition, Hirsch asserts no other object can be the norm of literary criticism than authorial meaning. One of the most useful tools for the objective detection of authorial meaning is the Sanger-Kroeber method—Sanger’s chronological study of the structure of fiction and Kroeber’s statistical quantification of formal elements. Its application to the analysis of Elizabeth Gaskell’s Mary Barton reveals that the novel’s central protagonist is the eponymous heroine, not her father as has been conventionally considered. Subjective readings will be superseded by new ones. But, readings based on objective data will not