172 research outputs found

    Augdaiyaku 1, Tajimat pujut augdaiyaku. Primer grado - Ciclo Inicial, portafolio de evidencias de Comunicación

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    Portafolio de evidencias para estudiantes del 1ergrado del ciclo intermedio. Propone conocimientos y relacionadas a actividades del área de Comunicación organizadas en cuatro unidades bajo los enfoques transversales del currículo, además contiene en cada unidad un proyecto que involucran las diversas competencias del área evidenciando el producto final de la unidad

    Augdaiyaku 1, Tajimat pujut augdaiyaku. Primer grado - Ciclo Intermedio, texto de Comunicación

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    Texto para estudiantes del 1ro.grado del ciclo intermedio. Propone conocimientos del área de Comunicación organizadas en cuatro unidades bajo los enfoques transversales del currículo, además contiene en cada unidad un proyecto que involucran las diversas competencias del área evidenciando el producto final de la unidad

    Augdaiyaku 3, Tajimat pujut augdaiyaku. Tercer grado - Ciclo Intermedio, texto de Comunicación

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    Texto para estudiantes del 3er grado del ciclo intermedio. Propone conocimientos del área de Comunicación organizadas en seis unidades bajo los enfoques transversales del currículo, además contiene en cada unidad un proyecto que involucran las diversas competencias del área evidenciando el producto final de la unidad

    Augdaiyaku 2, Tajimat pujut augdaiyaku. Segundo grado - Ciclo Inicial, portafolio de evidencias de Comunicación

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    Portafolio de evidencias para estudiantes del 2do grado del ciclo intermedio. Propone conocimientos y relacionadas a actividades del área de Comunicación organizadas en cuatro unidades bajo los enfoques transversales del currículo, además contiene en cada unidad un proyecto que involucran las diversas competencias del área evidenciando el producto final de la unidad

    A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-related

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    <p>Abstract</p> <p>Background</p> <p>The ageing of the worldwide population means there is a growing need for research on the biology of ageing. DNA damage is likely a key contributor to the ageing process and elucidating the role of different DNA repair systems in ageing is of great interest. In this paper we propose a data mining approach, based on classification methods (decision trees and Naive Bayes), for analysing data about human DNA repair genes. The goal is to build classification models that allow us to discriminate between ageing-related and non-ageing-related DNA repair genes, in order to better understand their different properties.</p> <p>Results</p> <p>The main patterns discovered by the classification methods are as follows: (a) the number of protein-protein interactions was a predictor of DNA repair proteins being ageing-related; (b) the use of predictor attributes based on protein-protein interactions considerably increased predictive accuracy of attributes based on Gene Ontology (GO) annotations; (c) GO terms related to "response to stimulus" seem reasonably good predictors of ageing-relatedness for DNA repair genes; (d) interaction with the XRCC5 (Ku80) protein is a strong predictor of ageing-relatedness for DNA repair genes; and (e) DNA repair genes with a high expression in T lymphocytes are more likely to be ageing-related.</p> <p>Conclusions</p> <p>The above patterns are broadly integrated in an analysis discussing relations between Ku, the non-homologous end joining DNA repair pathway, ageing and lymphocyte development. These patterns and their analysis support non-homologous end joining double strand break repair as central to the ageing-relatedness of DNA repair genes. Our work also showcases the use of protein interaction partners to improve accuracy in data mining methods and our approach could be applied to other ageing-related pathways.</p

    Augdaiyaku 2, Tajimat pujut augdaiyaku. Segundo grado - Ciclo Inicial, texto de Comunicación

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    Texto para estudiantes del 2do grado del ciclo inicial. Propone conocimientos del área de Comunicación organizadas en seis unidades bajo los enfoques transversales del currículo, además contiene en cada unidad un proyecto que involucran las diversas competencias del área evidenciando el producto final de la unidad

    What can metazoan parasites reveal about the taxonomy of Scomber japonicus Houttuyn in the coast of South America and Madeira Islands

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    The metazoan parasites of four populations of the chub mackerel Scomber japonicus were analysed from two localities in the Atlantic Ocean (Madeira Islands, Portugal, and Rio de Janeiro, Brazil) and two localities in the Pacific Ocean (Callao, Peru, and Antofagasta, Chile), collected during 2002 and 2003. A total of 373 fish specimens were studied and 34 metazoan parasite species were obtained. Parasites identified from the populations of chub mackerel studied could be separated into three categories: parasites with a wide distribution, present in the Pacific and Atlantic, parasites proper of the Pacific Ocean and parasites proper of the Atlantic Ocean. The analyses of some highly specific parasites of the genus Scomber (i.e. monogeneans of the genus Kuhnia and didymozoid digeneans) strongly suggest the need for a revision of the taxonomic status of chub mackerels from the Atlantic and Pacific coast of America. The results demonstrated the usefulness of parasites as adequate tools to clarify the taxonomic status of their hosts

    Motivation and incentives of rural maternal and neonatal health care providers: a comparison of qualitative findings from Burkina Faso, Ghana and Tanzania.

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    In Burkina Faso, Ghana and Tanzania strong efforts are being made to improve the quality of maternal and neonatal health (MNH) care. However, progress is impeded by challenges, especially in the area of human resources. All three countries are striving not only to scale up the number of available health staff, but also to improve performance by raising skill levels and enhancing provider motivation. In-depth interviews were used to explore MNH provider views about motivation and incentives at primary care level in rural Burkina Faso, Ghana and Tanzania. Interviews were held with 25 MNH providers, 8 facility and district managers, and 2 policy-makers in each country. Across the three countries some differences were found in the reasons why people became health workers. Commitment to remaining a health worker was generally high. The readiness to remain at a rural facility was far less, although in all settings there were some providers that were willing to stay. In Burkina Faso it appeared to be particularly difficult to recruit female MNH providers to rural areas. There were indications that MNH providers in all the settings sometimes failed to treat their patients well. This was shown to be interlinked with differences in how the term 'motivation' was understood, and in the views held about remuneration and the status of rural health work. Job satisfaction was shown to be quite high, and was particularly linked to community appreciation. With some important exceptions, there was a strong level of agreement regarding the financial and non-financial incentives that were suggested by these providers, but there were clear country preferences as to whether incentives should be for individuals or teams. Understandings of the terms and concepts pertaining to motivation differed between the three countries. The findings from Burkina Faso underline the importance of gender-sensitive health workforce planning. The training that all levels of MNH providers receive in professional ethics, and the way this is reinforced in practice require closer attention. The differences in the findings across the three settings underscore the importance of in-depth country-level research to tailor the development of incentives schemes

    Biological Activities of Polyphenols from Grapes

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    The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included
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