10 research outputs found
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
- Abarca-Gómez L.
- Abdeen Z.A.
- Abdrakhmanova S.
- Abdul Ghaffar S.
- Abdul Hamid Z.
- Abu-Rmeileh N.M.
- Abubakar Garba J.
- Acosta-Cazares B.
- Adams R.J.
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- Al-Hazzaa H.M.
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- Spinelli A.
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- Taylor A.
- Tchibindat F.
- Tebar W.R.
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- Vanuzzo D.
- Varela-Moreiras G.
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- Velika B.
- Veronesi G.
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- Wagner A.
- Waldhör T.
- Walton J.
- Wanderley Jr.
- Wang M.-D.
- Wang Q.
- Wang X.
- Wang Y.-W.
- Wang Y.X.
- Wannamethee S.G.
- Wan Bebakar W.M.
- Wan Mohamud W.N.
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- Weber A.
- Weerasekera D.
- Weghuber D.
- Wei W.
- Whincup P.H.
- Widhalm K.
- Widyahening I.S.
- Wiecek A.
- Wijga A.H.
- Wilks R.J.
- Willeit J.
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- Wu S.
- Xu H.
- Xu L.
- Yamborisut U.
- Yan W.
- Yang L.
- Yang X.
- Yang Y.
- Yardim N.
- Yaseri M.
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- Yiallouros P.K.
- Yngve A.
- Yoosefi M.
- Yoshihara A.
- You Q.S.
- You S.-L.
- Younger-Coleman N.O.
- Yusoff A.F.
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- Zafiropulos V.
- Zainuddin A.A.
- Zamani F.
- Zamani F.
- Zambon S.
- Zampelas A.
- Zamrazilová H.
- Zapata M.E.
- Zaw K.K.
- Zdrojewski T.
- Zeljkovic Vrkic T.
- Zeng Y.
- Zhao D.
- Zhao W.
- Zheng W.
- Zheng Y.
- Zholdin B.
- Zhou B.
- Zhou M.
- Zhu D.
- Zhussupov B.
- Zimmermann E.
- Zuñiga Cisneros a.
- Zuñiga Cisneros J.
- �ngquist L.H.
- Publication venue
- Publication date
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3�6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55 of the global rise in mean BMI from 1985 to 2017�and more than 80 in some low- and middle-income regions�was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing�and in some countries reversal�of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories. © 2019, The Author(s)
HBIG immunoprophylaxis of babies born to HBsAg carrier mothers
- Publication venue
- S. Kager
- Publication date
- 01/01/1983
- Field of study
Perinatal transmission of the hepatitis B virus and of the HBV-associated delta agent from mothers to offspring in northern Italy
- Author
- Publication venue
- 'Wiley'
- Publication date
- 01/01/1982
- Field of study
We report a prospective study on infants born to hepatitis B surface antigen (HBsAg) carrier mothers to estimate the incidence of perinatal transmission of HBV and HBV-associated delta agent in Northern Italy. The risk of infection to the infant was related to the presence of the HBe antigen-antibody system, HBV-specific DNA polymerase activity and antibody to delta in maternal sera, and to the titer of anti-HBe in babies at birth. The data of this study indicate: 1. Babies born to HBsAg carrier mothers with HBeAg in serum are at extremely high risk of acquiring HBV infection and of developing a chronic carrier state, whereas those born to anti-HBe-positive mothers are at a lower (P<.01) yet consistent risk of infection. 2. HBs antigenemia is usually prolonged and symptomatic in babies born to HBeAg-positive mothers while being self-limited and asymptomatic in babies born to anti-HBe-positive mothers. 3. DNA polymerase activity in maternal serum appears to be the most sensitive marker predicting HBV transmission to the infant since it was detected in all the HBeAg-positive mothers and also in two anti-HBe-positive mothers and in one HBeAg/anti-HBe-negative mother who transmitted infection to their babies. 4. High titers of anti-HBe (up to 1:103) do not prevent HBV infection. 5. Vertical transmission of delta infection seems to occur only in circumstances that permit perinatal transmission of HBV infection
Hepatitis C virus infection in a hematology ward: evidence for nosocomial transmission and impact on hematologic disease outcome
- Author
- Publication venue
- Publication date
- Field of study
Person and tense in narrative interpretation
- Author
- Almeida M. J.
- Almeida M.J.
- Alyssa Greene
- Aurora Mendelsohn
- Banfield A.
- Beattie A.
- Black J.B.
- Booth W.
- Boring E.G.
- Bresnan J.
- Brown G.
- Bruder G.A.
- Bruder G.A.
- Bryant D.J.
- Bühler K.
- Carol Hosenfeld
- Casparis C.P.
- Chaucer G.
- Cohn D.
- Comrie B.
- Couper‐Kuhlen E.
- Craik F.I.K.
- Duchan J.F.
- Duchan J.F.
- Emmott C.
- Erwin M. Segal
- Fillmore C.J.
- Fillmore C.J.
- Fish S.
- Franklin N.
- Franklin N.
- Galbraith M.
- Galbraith M.
- Gemsbacher M.A.
- Graesser A.C.
- Greenspan S.L.
- Gregory Miller
- Hamburger K.
- Heinggi D.
- Heinggi D.
- Hewitt L.E.
- Hyde T.S.
- James Julian
- Johnson‐Laird P.N.
- Joseph Delphonse
- Joyce J.
- Kintsch W.
- Kintsch W.
- Kirkham S.
- Li N.
- Magliano J.P.
- Maxwell W.H.
- Miall D.S.
- Miller G.
- Millis K.K.
- Minsky M.
- Morrow D.G.
- Morrow D.G.
- Mukherjee B.
- O'Henry
- Osgood C. E.
- Palmer F.
- Perlmutter D.
- Rapaport W.J.
- Reichenbach H.
- Schank R.C.
- Schopf A.
- Schopf A.
- Scott PJ.
- Searle J. R.
- Searle J.R.
- Segal E.M.
- Segal E.M.
- Segal E.M.
- Segal E.M.
- Segal E.M.
- Shapiro S.C.
- Siegel A.C.
- Taft K.B.
- Taylor H.A.
- Taylor H.A.
- van Dijk T.A.
- Wiebe J.A.
- Wiebe J.M.
- Wiebe J.M.
- William Russell
- Wilson A.
- Wittgenstein L.
- Yuhan A.H.
- Zubin D.A.
- Zwaan R.A.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Bacterial vaginosis: prevalence in outpatients, association with some micro-organisms and laboratory indices.
- Author
- Amsel R.
- Armitage P.
- Biondi M.
- Bramley H.M.
- Burmeister R.E.
- Chen K.C.S.
- Cristiano L.
- Durieux R.
- Eschenbach D.A.
- Eschenbach D.A.
- G Dalvai
- Gardner H.L.
- Gardner H.L.
- Gravett M.G.
- Hallen A.
- Hillier S.L.
- Hjeim E.
- HL I.Gardner
- Holst E.
- L Cristiano
- L Lorusso
- Leone F.
- M Lorenzi
- Magliano E.M.
- N Coffetti
- Paavonen J.
- Pheifer T.A.
- Phillips J.
- Piot P.
- Piot P.
- Roberts M.C.
- Rossi M.R.
- Rota G.
- Skarin A.
- Spiegel C.A.
- Spiegel C.A.
- Spiegel C.A.
- Spiegel C.A.
- Taylor E.
- Thomason J.L.
- Totten P.A.
- Vecchio T.J.
- Publication venue
- 'BMJ'
- Publication date
- Field of study
Parental Burden and its Correlates in Families of Children with Autism Spectrum Disorder: A Multicentre Study with Two Comparison Groups
- Author
- Angelo Picardi
- Antonella Gigantesco
- Bader S.H.
- Baker-Ericzen M.J.
- Barker E.T.
- Bartone P.T.
- Bartone P.T.
- Bartone P.T.
- Baxter A.J.
- Bayat M.
- Bebko J.M.
- Benson P.R.
- Benson P.R.
- Benson P.R.
- Bentler P.M.
- Bishop S.L.
- Blackledge J.T.
- Bromley J.
- Busner J.
- Carter A.S.
- Carver C.S.
- Carver C.S.
- Cidav Z.
- Clifford T.
- Conway J.M.
- Costigan C.L.
- Cotton S.M.
- Coyne J.C.
- Dam A.E.
- Davidson J.
- Davis N.O.
- Dumas J.E.
- Dykens E.M.
- Ekas N.V.
- Elsabbagh M.
- Emanuele Tarolla
- Estes A.
- Estes A.
- Falk N.H.
- Feinberg E.
- Firth I.
- Foody C.
- Franco Nardocci
- Gabriels R.L.
- Gau S.S.
- Gill M.J.
- Giovagnoli G.
- Gong Y.
- Grassi L.
- Gray D.E.
- Guido Alessandri
- Hall H.R.
- Hamlyn-Wright S.
- Harper A.
- Hastings R.P.
- Hastings R.P.
- Hayes A.F.
- Hayes S.A.
- Herring S.
- Hodge D.
- Hoefman R.
- Hogan B.E.
- Huws J.C.
- Ilaria Lega
- Ingersoll B.
- Karst J.S.
- Koegel R.L.
- Kogan M.D.
- Konstantareas M.M.
- Lavelle T.A.
- Lecavalier L.
- Lee L.C.
- Liptak G.S.
- Little L.
- Lord C.
- Lounds J.
- Lyons A.M.
- Magallón-Neri E.
- Magliano L.
- Magliano L.
- Magliano L.
- Magliano L.
- Manning M.M.
- Maurizio Cremonte
- McStay R.L.
- McStay R.L.
- Meldolesi G.N.
- Morosini P.L.
- Mugno D.
- Myers B.J.
- Obeid R.
- Olsson M.B.
- Olsson M.B.
- Ooi K.L.
- Osborne L.A.
- Ozonoff S.
- Pakenham K.I.
- Picardi A.
- Picardi A.
- Picardi A.
- Picardi A.
- Picardi A.
- Picardi A.
- Picardi A.
- Piccinelli M.
- Pind J.
- Pisula E.
- Power M.
- Reichow B.
- Renato Cerbo
- Rivard M.
- Ruiz-Robledillo N.
- Rushton J.P.
- Safe A.
- Satorra A.
- Schene A.H.
- Schopler E.
- Seymour M.
- Shaffer D.
- Sharpley C.F.
- Shimabukuro T.T.
- Siman-Tov A.
- Sivberg B.
- Smith L.E.
- Smith L.E.
- Smith L.E.
- Soltanifar A.
- Tehee E.
- Thoits P.A.
- Tomanik S.
- Totsika V.
- Twoy R.
- Vera Stoppioni
- Vohra R.
- Weiss J.A.
- Weiss M.J.
- Yirmiya N.
- Zaidman-Zait A.
- Zaidman-Zait A.
- Zimet G.D.
- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study
The Endeavours in RAS Inhibition - the Past, Present, and Future
- Author
- Abubaker J.
- Ahearn I.
- Ahmed Z.
- Ambrogio C.
- Anderson G.R.
- Appels N.M.G.M.
- Ashani Y.
- Balmain A.
- Banks M.
- Barault L.
- Basson M.A.
- Belov A.A.
- Berndt N.
- Bos J.L.
- Bos J.L.
- Bos J.L.
- Bourne H.R.
- Burns M.C.
- Buscail L.
- Canon J.
- Casey P.J.
- Casique-Aguirre D.
- Castellano E.
- Chandra A.
- Chang E.H.
- Chang F.
- Chen Z.
- Cheng Y.
- Cherfils J.
- Choy E.
- Clarke S.
- Collins M.A.
- Colombo S.
- Cox A.D.
- Cox A.D.
- Cox A.D.
- Cruz-Migoni A.
- Cruzalegui F.H.
- De Vos A.M.
- Der C.J.
- Deschenes R.J.
- di Magliano M.P.
- Dickson B.
- Downward J.
- Durrant D.E.
- Ellis R.W.
- Engelman J.A.
- Fasano O.
- Ferrer I.
- Fields J.
- Fiordalisi J.J.
- Forrester K.
- Fukui Y.
- Fukui Y.
- Galiè M.
- Gallego C.
- Ganguly A.K.
- Ge C.
- Gibbs J.B.
- Gorfe A.A.
- Graziano S.L.
- Guerrero I.
- Gupta S.
- Gutierrez L.
- Hager G.L.
- Haigis K.M.
- Halilovic E.
- Hall A.
- Hallin J.
- Han C.W.
- Hancock J.F.
- Hansen M.
- Hart K.C.
- Harvey J.J.
- Head J.
- Heng H.H.
- Hennessy B.T.
- Hesketh R.
- Hobbs G.A.
- Hoeflich K.P.
- Hofer F.
- Howe L.R.
- Hunter J.C.
- Hunter J.C.
- Hurley J.B.
- Jones R.P.
- Kamata T.
- Karaguni I-M.
- Katso R.
- Kazi A.
- Keeton A.B.
- Kikuchi A.
- Kim R-K.
- Kirsten W.H.
- Knijn N.
- Kodaz H.
- Kramer Ij.
- Krengel U.
- Kyriakis J.M.
- Ledford H.
- Li S.
- Lim S.M.
- Liu F.
- Liu P.
- Lu S.
- Maffucci T.
- Malaquias A.C.
- Malhotra S.
- Malumbres M.
- Manne V.
- Margolis B.
- Martini M.
- Maurer T.
- McCubrey J.A.
- McGrath J.P.
- Milburn M. V
- Missero C.
- Moodie S.A.
- Mulcahy L.S.
- Murugan A.K.
- Mörchen B.
- Müller M.P.
- Müller S.
- Nagaria T.S.
- Nagasaka M.
- Nussinov R.
- Nussinov R.
- Ollikainen M.
- Ostrem J.M.
- Ostrem J.M.L.
- Pacold M.E.
- Pagon Z.
- Pai E.F.
- Pai E.F.
- Parada L.F.
- Pearson G.
- Peyssonnaux C.
- Porru M.
- Prior I.A.
- Quan Y.
- Quilliam L.A.
- Rajalingam K.
- Rajasekharan S.K.
- Reddy E.P.
- Robinson L.C.
- Rodriguez-Viciana P.
- Rodriguez-Viciana P.
- Román M.
- Rotblat B.
- Rowinsky E.K.
- Sanaei S.
- Scheffzek K.
- Scheffzek K.
- Schlichting I.
- Schmick M.
- Scolnick E.M.
- Scolnick E.M.
- Scolnick E.M.
- Serebriiskii I.G.
- Seton-Rogers S.
- Sheridan C.
- Shih T.Y.
- Shih T.Y.
- Shima F.
- Shimizu H.
- Shimizu K.
- Shimizu K.
- Shimizu K.
- Siegel R.L.
- Sjölander A.
- Smit V.T.
- Smith M.R.
- Sos M.L.
- Spaargaren M.
- Spiegel J.
- Spoerner M.
- Stephen A.G.
- Stevens K.N.
- Su F.
- Su H.
- Sukumar S.
- Sweet R.W.
- Sánchez-Muñoz A.
- Tabin C.J.
- Taveras A.G.
- Temraz S.
- Toma-Fukai S.
- Tong L.
- Tong L.A.
- Trahey M.
- Tsai F.D.
- Tsuchida N.
- Urano T.
- Van Aelst L.
- Vogt A.
- Vojtek A.B.
- Waldmann H.
- Wang J.
- Warne P.H.
- Wee S.
- Weinberg R.A.
- Wennerberg K.
- Westcott P.M.K.
- Westover K.D.
- Willingham M.C.
- Willumsen B.M.
- Wong K-K.
- Wood K.W.
- Yan C.
- Yang H.
- Yang J.
- Yang S.
- Yuan T.L.
- Zarich N.
- Zhang X-F.
- Zhang X.
- Zhang Z.
- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
- Publication venue
- Publication date
- 01/01/2021
- Field of study
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions. © Copyright
Overview of Current Immunotherapies Targeting Mutated KRAS Cancers
- Author
- Allahyari H.
- Amanam I.
- Ancliff P.J.
- Anderson R.J.
- Ascierto P.A.
- Bader T.
- Beatty P.L.
- Besser M.J.
- Bonifant C.L.
- Bos R.
- Braumüller H.
- Brämswig K.H.
- Buhrman J.D.
- Bustinza-Linares E.
- Chaft J.E.
- Chan B.A.
- Chase J.L.
- Chaurasiya S.
- Chmielewski M.
- Cohen E.P.
- Conroy T.
- Corcoran R.B.
- Cox A.D.
- Cutts F.T.
- Danielsen S.A.
- Deacon D.H.
- di Magliano M.P.
- Dobre M.
- Dudley M.E.
- Einstein M.H.
- Ekblad M.
- Emens L.A.
- Enblad G.
- Engelman J.A.
- Farkona S.
- Fernández-Medarde A.
- Ferrer I.
- Fiedler K.
- Fioretti D.
- Fishman M.
- FitzGerald D.J.
- Forcella M.
- Fotin-Mleczek M.
- Fotin-Mleczek M.
- François V.
- Fu Y.J.
- Fukazawa T.
- Garassino M.C.
- Gardner T.A.
- Geresu M.A.
- Ghetie V.
- Gil M.
- Goff S.L.
- Goffin J.
- Golay H.G.
- Gore L.
- Graff J.N.
- Grunwitz C.
- Hafner C.
- Hagan S.
- Hammerstrom A.E.
- Hansen T.F.
- Hartley M.L.
- Hata A.N.
- Hobbs G.A.
- Huang Y.
- Hurley L.P.
- Infante J.R.
- Irahara N.
- Jancík S.
- Janssen E.M.
- Jeanbart L.
- Jensen-Jarolim E.
- Jiang B.
- Jiang S.S.
- Jinesh G.G.
- Kakimi K.
- Kantor J.
- Karoulia Z.
- Kasper B.
- Kass E.
- Katsuda M.
- Kawalec P.
- Keenan B.P.
- Khosravi N.
- Kim L.
- Knittelfelder R.
- Kochenderfer J.N.
- Kodaz H.
- Kota J.
- Koury J.
- Kozbor D.
- Kreiter S.
- Laheru D.
- Larocca C.
- Lau T.P.
- Lee H.S.
- Lee S.
- Leffers N.
- Li J.
- Li W.
- Lin E.
- Lin Y.
- Lionel L.A. In
- Lito P.
- Liu M.
- Lokhov P.G.
- Lujambio A.
- Lundstrom K.
- Lundstrom K.
- Luo W.
- Lynch T.J.
- MacGregor R.R.
- Martinon F.
- Masoud V.
- Matthews K.S.
- Meiliana A.
- Melero I.
- Meng F.P.
- Miliotou A.N.
- Miller V.A.
- Mitchell D.A.
- Miyamoto Y.
- Mohebtash M.
- Molina-Arcas M.
- Nair S.K.
- Nemunaitis J.
- Ng A.W.R.
- Oiseth S.J.
- Ostrem J.M.L.
- Palmer D.H.
- Palucka K.
- Pan J.
- Pardoll D.M.
- Patricelli M.P.
- Perosa F.
- Pilon-Thomas S.
- Pirker R.
- Porru M.
- Postow M.A.
- Probst J.
- Probst J.
- Pui Yan Siak
- Quezada S.A.
- Radvanyi L.G.
- Rajasekharan S.K.
- Ranpura V.
- Raper S.E.
- Rausch S.
- Ribas A.
- Riches J.C.
- Riley R.S.
- Rinaldi M.
- Rittig S.M.
- Román M.
- Rosenberg S.A.
- Rosenberg S.A.
- Rosenberg S.A.
- Rosenberg S.A.
- Rosenberg S.A.
- Sabado R.L.
- Sadelain M.
- Sahin U.
- Sandler A.
- Sandler A.B.
- Sanmamed M.F.
- Sayour E.J.
- Scheel B.
- Schiedner G.
- Schlake T.
- Schlom J.
- Schuler G.
- Sebastian M.
- Shaib W.
- Shanmugam A.
- Shapira S.
- Sharma A.
- Sharma P.
- Simanshu D.K.
- Simons J.W.
- Singer J.
- Slingluff C.L.
- Smith A.J.
- Smith H.A.
- Soulières D.
- Speiser D.E.
- Srivatsan S.
- Stambrook P.J.
- Syn N.L.
- Tan C.
- Tang H.
- Thomas M.C.
- Tian H.
- Topalian S.L.
- Tran E.
- van Krieken J.H.
- Von Hoff D.D.
- Wada S.
- Wagner S.
- Walter S.
- Wang F.
- Wang M.
- Wedén S.
- Wei G.
- Weinberg F.D.
- Weng T.Y.
- Winfrey Pui Yee Hoo
- Xiang B.
- Xie Y.
- Yaddanapudi K.
- Yamamoto A.
- Yang B.
- Yang J.
- Yang L.
- Ye Z.
- Zeichner S.B.
- Zeitouni D.
- Zhang H.
- Zhao Z.
- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study