Fortification of food with micronutrients: development of methodological and regulatory framework in the Russian Federation

The available scientific literature, domestic and international regulatory codes of normative documents concerning the fortification of various types of food products have been analyzed. The groups of food products of conventional and regular consumption included into the diets of all categories of consumers, recommended for fortification with essential micronutrients, have been determined: wheat and cereal flour (spelt wheat, buckwheat, oat, corn flour, etc.); pastry; milk and dairy products, including ice cream; non-alcoholic soft drinks; mineralized drinking water; fruit and vegetable juices; fat and oil products (vegetable oils, margarines, spreads, mayonnaise); confectionery and sweets (pastry, sugar, chocolate); cereals (breakfast cereals, muesli, ready-to-eat extruded cereals, instant pasta and cereals, mixtures for bakery, flour for sweet pastry); food concentrates (jelly, instant drinks, concentrates of sweet foods, instant food, instant cereal concentrates); table salt. The groups of food products assigned for certain categories of population are used as part of therapeutic diets for patients with various diseases (metabolic disorder syndrome, cardio-vascular system pathology with atherosclerotic vascular injury, type 2 diabetes mellitus, gastrointestinal tract diseases, non-alcoholic fatty liver disease, diabetic nephropathy, etc.), as well as assigned to reduce the risk of diseases developing, the nutrients are recommended for targeted fortification of certain types of food. Examples of micronutrients fortification of sausages and minced meat semifinished products are given below. Requirements for fortification of mass consumption food products and for fortification of foods for special dietary uses are formulated in this article, the amount of fortifying components in the various groups of food products are justified, ensuring their efficiency for improving the micronutrient status and safety of its consumption. Based on the analysis of the available scientific literature, domestic and international regulatory framework of normative documents on fortification of various types of food products, recommendations have been developed for fortification of food with micronutrients

Sea buckthorn cultivars promising for mechanized harvesting by cutting fruit-bearing branches

Background. Sea buckthorn (Hippophae rhamnoides L.) is the main berry crop in the horticultural production of Altai Territory and occupies the largest growing area among berries in Russia. Meanwhile, further expansion of commercial plantations is limited by known bottlenecks in harvesting. In this context, new technological solutions in harvest mechanization are considered one of the primary tasks. A promising way is the cutting of fruit-bearing branches. At the same time, the development of cultivars suitable for such harvesting technique is very important.Materials and methods. Thirteen cultivars and selected forms of sea buckthorn developed at the Federal Altai Scientific Center of Agro-Biotechnologies were taken as research material. To evaluate the productivity of top branches, three of them with a length of 70–100 cm were cut from the plants of each accession. Fruit detachment force was assessed using a Dina-2 device. Dispersion analysis was applied for statistical interpretation.Results. Productivity of top branches as well as agronomic and biological characteristics of sea buckthorn fruits were studied. Accessions 87-93-1, 111-05-3 and 378-06-1 were identified for high productivity of their top branches and for predomination of the generative part over the vegetative one. The highest number of berries per bud (5.4–5.9 pieces) was observed in accessions 87-93-4, 32-01-1, 378-06-1 and 111-05-3. Cv. ‘Afina’ demonstrated for its high level of vegetative and generative productivity. Selected forms 111-05-3, 32-01-1 and 4-93-11 with low fruit detachment force (136.8–155.1 g) are promising for shaking without prior freezing.Conclusion. Selected forms 111-05-3, 378-06-1 and 32-01-1 were recognized as most promising for harvesting by branch cutting

Multi-Drug Resistance of Mycobacterium Tuberculosis – the Problem of Modern Phthisiology

The 21st century is characterized by the exacerbation of the problem formation and spreading of drug-resistant strains throughout the world. Genetic mutations of Mycobacterium tuberculosis lead to the formation of drug-resistant forms because of long-term use of anti-tuberculosis drugs. The Russian Federation is among the top three countries with a high burden of tuberculosis with multidrug resistance (MDR). The estimated number of cases of tuberculosis with MDR in the Russian Federation was 60,000, which corresponds to half the burden of the European Region in 2015. In the Irkutsk region from 2014 till 2018 the proportion of TB cases with MDR cases increased from 15.2 % to 18.3 %. According to the reference laboratory of the Irkutsk Regional Clinical Tuberculosis Hospital, a significantly higher level of MDR among primary diagnosed was registered in the cities (27.7 %) and the lowest in rural areas of the region (16.5 %). Among the cohorts of patients with tuberculosis, the highest proportion of MDR was in the northern territories of the region (43.1 %), in Irkutsk district (41.2 %) and in large cities, including Irkutsk (38.5 %). Positive correlations were established between cohort of primary diagnosed TB with MDR and among populations in areas with high morbidity along the railway (r = 0.91; p = 0.00001), in the Irkutsk region (r = 0.89; p = 0,00008), and also in the Irkutsk city (r = 0.91; p = 0.00002). This is probably due to the influence of reservoir of tuberculosis infection formed in these localities. The regulatory documents of the Ministry of Health of the Irkutsk Region was developed on the basis of the data obtained, and they include recommendations for improving the diagnosis of tuberculosis in the region using fast and accelerated microbiological diagnostic methods

Project approach to training teachers for secondary vocational education

При проектном подходе к подготовке педагогических кадров для среднего профессионального образования изменяются взаимоотношения между заказчиками – учебными заведениями СПО и профессионально-педагогическим вузом, отвечающим за подготовку квалифицированных педагогов профессионального обученияThe design approach to the preparation of teachers for secondary vocational education changed the relationship between customers – educational institutions of secondary vocational and vocational-pedagogical University responsible for the training of qualified, meeting the requirements of the act, teachers of vocational trainin

Viability of causative pathogen in patients with drug-sensitive and drug-resistant forms of respiratory tuberculosis

To predict outcomes of tuberculosis we investigated the viability of Mycobacterium tuberculosis (MTB) in relation to drug resistance of strains and clinical manifestations of tuberculosis. During the study on solid Löwenstein - Jensen medium, we determined the speed, growth rate and drug resistance of MBT in 5945 cultures, isolated from the sputum of patients with pulmonary tuberculosis - residents of the Irkutsk region (2193 -from newly diagnosed patients, 3752 - from previously treated patients). The criterion of high viability of MBT was the growth rate of >100 colonies over 20 days; and low viability corresponded with the growth rate of 30 days. 2171 cultures (36.5 %) had high viability of MBT strains, 3021 (50.8 %) - low, and 753 (12.7 %) cultures had average degree of viability. A high degree of pathogen viability was more often determined in newly diagnosed patients with tuberculosis of intrathoracic lymph nodes (all patients with HIV-infection without antiretroviral therapy), fibrotic-cavernous and infiltrative tuberculosis. Among previously treated patients with tuberculosis the high viability of MBT was often determined in patients with fibrous-cavernous and infiltrative tuberculosis, and caseous pneumonia. Cultures from previously treated patients with tuberculosis of intrathoracic lymph nodes had low degree of viability. The number of drug-sensitive strains was 1992, drug-resistant ones - 3953, including 1430 strains with multidrug resistance. We have found that 37.5 % drug-resistant strains associated with a high degree of viability (multidrug resistance - 38.5 %), it's was more often than the drug-sensitive (35.4 %; p < 0.01)

Значение качества жизни, связанного со здоровьем, у больных системной красной волчанкой и современные инструменты его оценки

The paper presents an overview of studies assessing health-related quality of life (HRQoL) in patients with systemic lupus erythematosus (SLE). It describes the HRQoL concept and prerequisites for its creation. The classification of questionnaires used in patients with SLE is considered in relation to the study objectives. The main key triad (fatigue, pain, and depression), which causes a reduction in HRQoL in SLE patients, is derived on the basis of many studies. The paper provides brief comparative characteristics of eight specific HRQoL questionnaires in SLE patients: Symptom checklist (SSC), SLEQol, LupusQol, L-QoL, LupusPRO, and Lupus Impact Tracker (LIT), LUP-QoL, and SMILEY. Special attention is paid to HRQoL assessment in patients receiving different treatment options: glucocorticoids, cytostatic and anti-B-cell therapy. Представлен обзор исследований, посвященных оценке качества жизни, связанного со здоровьем (КЖСЗ), у больных системной красной волчанкой (СКВ). Описаны концепция КЖСЗ, а также предпосылки ее создания. Рассмотрена классификация опросников, применяемых у пациентов СКВ, в зависимости от задач, поставленных в исследовании. У больных СКВ на основании многих исследований выведена основная ключевая триада проблем (усталость, боль и депрессия), вызывающая ухудшение КЖСЗ. Приведена краткая сравнительная характеристика восьми специфических опросников для оценки КЖСЗ у больных СКВ: SLE Symptom checklist (SSC), SLEQol, LupusQol, L-Qol, LupusPRO и Lupus Impact Traker (LIT), LUP-QoL, SMILEY. Отдельное внимание уделено оценке КЖСЗ у больных, получающих разные виды лечения: глюкокортикоиды, цитостатическую, анти-В-клеточную терапию.

Экологическое состояние животноводства и птицеводства в приграничных районах России и Юго-Восточной Финляндии

Intensifi cation of agricultural production increases the burden on the environment. Modern management and planning of agricultural activity requires a comprehensive assessment of the environmental status of the industry. (Research purpose) To develop recommendations for improving the environmental safety of agricultural production based on the implementation of the best available technologies, methods for monitoring and controlling technological processes for the disposal of organic animal waste. (Materials and methods) The authors studied agricultural enterprises, their specialization and production capacities, technologies for manure and litter utilization. The studies included an assessment of enterprises according to the criteria approved in the recommendations of Helsinki Commission for the Baltic Sea. The authors used standard methods for processing statistical, fi eld and personal data. (Results and discussion) The authors conducted a state analysis of the agro-industrial complex of Leningrad Region in terms of the organic waste formation from animal husbandry and poultry farming, and evaluated the potential for their use. They studied 142 large complexes, which produce more than 90 percent of livestock and poultry products. The average livestock density in Leningrad Region is 2.2 conventional heads per hectare of cultivated agricultural land. They showed that there are 22,200 households in southern Finland, 79 percent of which are plant growing enterprises that are engaged in small-scale production. They took into account the specifi c features of the studied territories in terms of nutrient load and proposed a system of environmental impact regulation. (Conclusions) The authors developed 4 main recommendation sections to reduce the risks of biogenic environmental pollution: the development of an industrial environmental control system based on technological regulations; mastering the system of regional monitoring and coordination of work with organic fertilizers; adoption and implementation of a program of livestock enterprises technological and technical modernization in terms of the organic waste disposal; creation of demonstration platforms for environmental specialists advanced training in the implementation of modern technological solutions.Интенсификация аграрного производства увеличивает нагрузку на окружающую среду. Современное управление и планирование сельскохозяйственной деятельности требует комплексной оценки экологического состояния отрасли. (Цель исследования) Разработать рекомендации для повышения экологической безопасности сельхозпроизводства на основе внедрения наилучших доступных технологий, методов мониторинга и управления технологическими процессами утилизации органических отходов животноводства. (Материалы и методы) Изучили сельскохозяйственные предприятия, их специализацию и производственные мощности, технологии утилизации навоза и помета. Включили в исследования оценку предприятий по критериям, утвержденным в рекомендациях Хельсинской комиссии по Балтийскому морю. Применили стандартные методы обработки статистических, натурных и анкетных данных. (Результаты и обсуждение) Провели анализ состояния агропромышленного комплекса Ленинградской области в части образования органических отходов животноводства и птицеводства, оценили потенциал их использования. Исследовали 142 крупных комплекса, на которых производится более 90 процентов продукции животноводства и птицеводства. Средняя плотность поголовья животных в Ленинградской области составляет 2,2 условной головы на один гектар обрабатываемых сельскохозяйственных земель. Показали, что в Южной Финляндии насчитывается 22200 хозяйств, из них 79 процентов – растениеводческие, которые занимаются мелкотоварным производством. Учли особенности исследуемых территорий по биогенной нагрузке и предложили систему регулирования воздействия на окружающую среду (Выводы) Разработали 4 основных раздела рекомендаций по снижению рисков биогенного загрязнения окружающей среды: освоение системы производственного экологического контроля на основе технологических регламентов; освоение системы регионального мониторинга и координации работы с органическими удобрениями; принятие и выполнение программы технологической и технической модернизации животноводческих предприятий в части утилизации органических отходов; создание демонстрационных площадок для повышения квалификации специалистов по экологическим вопросам внедрения современных технологических решений

New Online Ecology of Adversarial Aggregates: ISIS and beyond

Support for extremist entities - whether from the far right, or far left - often manages to survive globally online despite significant external pressure, and may ultimately inspire violent acts by individuals having no obvious prior history of extremism. Examining longitudinal records of extremist online activity, we uncovered an ecology evolving on a daily timescale that drives online support, and we provide a mathematical theory that describes it. The ecology features self-organized aggregates (online groups such as on Facebook or another social media analog) that proliferate preceding the onset of recent real-world campaigns, and adopt novel adaptive mechanisms to enhance their survival. One of the predictions is that development of large, potentially potent online groups can be thwarted by targeting smaller ones.Comment: Similar to version that appeared in Science (2016

Pedagogical conditions of college students’ core competencies formation in the process of foreign languages learning

© 2016, Econjournals. All rights reserved.The relevance of the problems stated in the article is conditioned by the fact that with the expansion of international economic relations and the increasing number of joint ventures and companies, there is an urgent need for specialists capable of intercultural communication for the implementation of the business contacts and contracts, the conclusion of economic agreements with foreign partners, cooperating with enterprises of different countries. In this regard, this article is aimed at identifying and studying of the pedagogical conditions of college students’ core competencies formation in the process of foreign languages learning. The article clarifies the composition of core competencies in college students’ foreign languages learning; identifies a set of criteria for selection of the content of discipline “foreign language;” reveals the effectiveness of pedagogical technologies of college students’ core competencies formation in the foreign languages learning; provides quality monitoring technology of college students’ core competencies formation in the process of foreign languages learning