139 research outputs found

    Gastritis and gastroesophageal reflux disease are strongly associated with non-allergic nasal disorders

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    Background: Gastroesophageal reflux disease (GERD) has been reported to be significantly associated with chronic rhinosinusitis, but the strength of the association is still debated. Aims: To evaluate the strength of the association between gastritis/GERD and non-allergic rhinitis (NAR)/allergic rhinitis (AR)/sinusitis. Methods: We investigated 2887 subjects aged 20–84 years, who underwent a clinical visit in seven Italian centres (Ancona, Palermo, Pavia, Terni, Sassari, Torino, Verona) within the study on Gene Environment Interactions in Respiratory Diseases, a population-based multicase-control study between 2008 and 2014. Subjects were asked if they had doctor-diagnosed “gastritis or stomach ulcer (confirmed by gastroscopy)” or “gastroesophageal reflux disease, hiatal hernia or esophagitis”. The association between NAR/AR/sinusitis and either gastritis or GERD was evaluated through relative risk ratios (RRR) by multinomial logistic regression. Results: The prevalence of gastritis/GERD increased from subjects without nasal disturbances (22.8% = 323/1414) to subjects with AR (25.8% = 152/590) and further to subjects with NAR (36.7% = 69/188) or sinusitis (39.9% = 276/691). When adjusting for centre, sex, age, education level, BMI, smoking habits and alcohol intake, the combination of gastritis and GERD was associated with a four-fold increase in the risk of NAR (RRR = 3.80, 95% CI 2.56–5.62) and sinusitis (RRR = 3.70, 2.62–5.23) with respect to controls, and with a much smaller increase in the risk of AR (RRR = 1.79, 1.37–2.35). Conclusion: The study confirmed the association between gastritis/GERD and nasal disturbances, which is stronger for NAR and sinusitis than for AR

    Topics in Mathematical Analysis

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    This volume contains most of the lectures of the "Minicorsi of Mathematical Analysis" held at the University of Padova in the years 2000-2003

    JPN Guidelines for the management of acute pancreatitis: severity assessment of acute pancreatitis

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    This article addresses the criteria for severity assessment and the severity scoring system of the Ministry of Health and Welfare of Japan; now the Japanese Ministry of Health, Labour, and Welfare (the JPN score). It also presents data comparing the JPN score with the Acute Physiology and Chronic Health Evaluation (APACHE) II score and the Ranson score, which are the major measuring scales used in the United States and Europe. The goal of investigating these scoring systems is the achievement of earlier diagnosis and more appropriate and successful treatment of severe or moderate acute pancreatitis, which has a high mortality rate. This article makes the following recommendations in terms of assessing the severity of acute pancreatitis

    Gli anni ’70 e la Scuola Normale

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    The Author focuses on the role played by the Scuola Normale Superiore in Pisa during the 1970s and 1980s in the development of computer applications in archaeology and art history. The roots of this activity can be traced to the post-war period in the 1950s; these were years full of constructive optimism which, during the 1960s led to the design and construction of the CEP (Calcolatrice Elettronica Pisana), to the first academic Degree in Computer Science at the University of Pisa, and to the creation of CNUCE (Centro Nazionale Universitario di Calcolo Elettronico). This latter was founded in order to coordinate the various scientific and educational activities and support computer-based research also in marginal and newly established fields. Several important initiatives resulted from the cooperation with the Istituto Centrale per il Catalogo e la Documentazione, directed by Oreste Ferrari. Computer Science was introduced at the Scuola Normale Superiore as an approach to the problems related to the automatic processing of archaeological and art history data and documents, thanks to Paola Barocchi and the creation of the Centro di Elaborazione Automatica di Dati e Documenti Storico Artistici, which established important international relationships with the Paul Getty Foundation, the Harvard University Center for Italian Renaissance Studies at Villa I Tatti, the Warburg Institute, etc
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