23 research outputs found
Practice of spiritual-commercial movement as a phenomenon of the consumer society
Π‘ΠΏΠΈΡΠΈΡΡΠ°Π»ΡΠ½ΠΎ-ΠΊΠΎΠΌΠΌΠ΅ΡΡΠ΅ΡΠΊΠΎΠ΅ Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΠ΅ ΠΎΠ΄ΠΈΠ½ ΠΈΠ· ΡΡΡΠ°ΠΉΡΠΈΡ
ΠΏΡΠΈΠΌΠ΅ΡΠΎΠ² Π²Π»ΠΈΡΠ½ΠΈΡ ΠΎΠ±ΡΠ΅ΡΡΠ²Π° ΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΡ Π½Π° ΠΎΠ±Π»Π°ΡΡΡ ΡΠ΅Π»ΠΈΠ³ΠΈΠΈ, Π±ΠΎΠ»Π΅Π΅ ΡΠΎΠ³ΠΎ, Π²Π»ΠΈΡΠ½ΠΈΡ ΠΏΠ°ΡΠ°Π΄ΠΈΠ³ΠΌΡ ΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΡ Π½Π° Π΄ΡΡ
ΠΎΠ²Π½ΡΡ ΠΆΠΈΠ·Π½Ρ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ°. Π‘ΡΡΠ΅ΡΡΠ²ΡΠ΅Ρ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ° Π°ΡΡΠΈΠ±ΡΡΠΈΠΈ ΡΠΏΠΈΡΠΈΡΡΠ°Π»ΡΠ½ΠΎ-ΠΊΠΎΠΌΠΌΠ΅ΡΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΡ ΠΊΠ°ΠΊ ΡΠ΅Π»ΠΈΠ³ΠΈΠΎΠ·Π½ΠΎΠ³ΠΎ ΡΠ²Π»Π΅Π½ΠΈΡ. ΠΠ° Π½Π°Ρ Π²Π·Π³Π»ΡΠ΄ Π²ΡΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ Π΅Π³ΠΎ Π·Π° ΡΠ°ΠΌΠΊΠΈ ΡΠ΅Π»ΠΈΠ³ΠΈΠΎΠ·Π½ΠΎΠ³ΠΎ ΡΠ²ΠΎΠ΄ΠΈΡ Π½Π°Ρ ΠΎΡ ΠΏΠΎΠ½ΠΈΠΌΠ°Π½ΠΈΡ Π΄ΡΡ
ΠΎΠ²Π½ΡΡ
ΠΎΡΠ½ΠΎΠ² ΡΡΠΎΠ³ΠΎ ΡΠ΅Π½ΠΎΠΌΠ΅Π½Π°. Π ΡΠ΄ Π°ΡΠΏΠ΅ΠΊΡΠΎΠ² ΡΠΏΠΈΡΠΈΡΡΠ°Π»ΡΠ½ΠΎ-ΠΊΠΎΠΌΠΌΠ΅ΡΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΡ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°Π΅ΡΡΡ Π² ΡΡΠ°ΡΡΠ΅: Π΅Π³ΠΎ ΡΠ΅Π»ΠΈΠ³ΠΈΠΎΠ·Π½ΡΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ, ΠΏΡΠΈΠ²Π΅ΡΠΆΠ΅Π½Π½ΠΎΡΡΡ Π½Π΅ΠΊΠ»Π°ΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΠΈΠΊΠ΅, ΡΠ²ΡΠ·Ρ Ρ ΠΏΠ°ΡΠ°Π΄ΠΈΠ³ΠΌΠΎΠΉ ΠΏΠΎΡΡΠ΅Π±Π»Π΅Π½ΠΈΡ. Π ΡΠ°Π±ΠΎΡΠ΅ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°Π΅ΡΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΏΠΎΠ½ΡΡΠΈΡ ΠΏΠΎΡΡΠ΅Π±ΠΈΡΠ΅Π»ΡΡΠΊΠΎΠΉ ΠΈΠ΄Π΅Π½ΡΠΈΡΠ½ΠΎΡΡΠΈ, ΠΊΠΎΡΠΎΡΠΎΠ΅ ΡΠΈΡΠΎΠΊΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΠ΅ΡΡΡ Π² ΠΌΠ°ΡΠΊΠ΅ΡΠΈΠ½Π³ΠΎΠ²ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΡ
, Π΄Π»Ρ ΠΎΠΏΠΈΡΠ°Π½ΠΈΡ ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π»ΡΠ΄Π΅ΠΉ Π²Ρ
ΠΎΠ΄ΡΡΠΈΡ
Π² Π‘ΠΠ (ΡΡΠ°ΡΡΠ½ΠΈΡ ΠΆΠ΅Π½ΡΠΊΠΈΡ
ΠΏΡΠ°ΠΊΡΠΈΠΊ). ΠΠ΅Π½ΡΠΊΠΈΠ΅ ΠΏΡΠ°ΠΊΡΠΈΠΊΠΈ ΡΡΠΎ ΠΏΡΠ°ΠΊΡΠΈΠΊΠΈ, ΠΎΡΠ½ΠΎΡΡΡΠΈΠ΅ΡΡ ΠΊ ΡΠΏΠΈΡΠΈΡΡΠ°Π»ΡΠ½ΠΎ-ΠΊΠΎΠΌΠΌΠ΅ΡΡΠ΅ΡΠΊΠΎΠΌΡ Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΡ, ΡΠΎΠ΄Π΅ΡΠΆΠ°ΡΠΈΠ΅ ΠΈΠ΄Π΅ΠΈ ΡΠ΅Π»ΠΈΠ³ΠΈΠΎΠ·Π½ΠΎΠ³ΠΎ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ°, Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΡΠ΅ Π½Π° Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΠ΅ "ΠΆΠ΅Π½ΡΡΠ²Π΅Π½Π½ΠΎΡΡΠΈ". Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΡΡΠ΄Π° ΡΠΏΠΈΡΠΈΡΡΠ°Π»ΡΠ½ΠΎ-ΠΊΠΎΠΌΠΌΠ΅ΡΡΠ΅ΡΠΊΠΈΡ
Π΄Π²ΠΈΠΆΠ΅Π½ΠΈΠΉ Π‘ΡΠ΅Π΄Π½Π΅Π³ΠΎ Π£ΡΠ°Π»Π° ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ Π² Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΠ΅.Spiritual-commercial movement is one of the most striking examples of the impact of the consumer society on the sphere of religion. Moreover, it is the influence of the consumption paradigm on the spiritual life of man. There is a problem of attribution of the spiritual-commercial movement as a religious phenomenon. In our view moving it away from the realm of the religious leads us away from understanding the spiritual foundations of this phenomenon. Several aspects of spiritual-commercial movement are considered in this article: its religious character, commitment to non-classical ethics, and connection with the consumption. In this research discussed the possibility of applying the concept of consumer identity, which is widely used in marketing research, as a tool to describe the behavior of people why practice SCM (the women's practices participators). Women's practices are belonged to spiritually-commercial movement, contain religious ideas, help to achieve "femininity". The results of several studies of the spiritual-commercial movements of the Middle Urals are presented in this paper.ΠΡΠΎΠ³ΡΠ°ΠΌΠΌΠ° ΡΠ°Π·Π²ΠΈΡΠΈΡ Π£ΡΠ€Π£ Π½Π° 2013 Π³ΠΎΠ΄ (ΠΏ.2.1.2.1
Middle-range theories in religion and media studies: Mediation, mediatization and rsst
The article explores three seminal approaches to the study of religion and media: Mediatization theory, mediation theory, and religioussocial shaping of technology ( RSST). The overview gives a comparative analysis of these approaches considering the relation between the genesis and conceptual frame of each approach and the scope and boundaries of its application. Firstly, we focus on the difference in the conceptualization of the relation of media and religion. The theory of mediatization emphasizes the transformation of religion by media, the theory of mediation studies media as a part of religious practices, and RSST is concerned with shaping of media technologies by religious communities. Secondly, we outline that the discussed approaches differ in their interpretations of religion, which is crucial in defining the level of the analysis. While the conceptual frameworks of institutional tradition of mediatization theory and RSST address the institutionalized forms of religions, other approaches are suitable for the study of religious institutions as well as individual "lived religion". The general optic, the scope and the boundary of each approach is defined by the way religion is related to the media, and by the level of analysis. Β© 2020 Russian Presidential Academy of National Economy and Public Administration. All rights reserved
Traditionalist orthodox christian media: Discourse structure and peculiarities of the functioning
The article considers how the traditionalist Orthodox groups use print and online media for retranslation of their version of Orthodoxy or their model of religious identity. The Orthodox traditionalists focus on the promotion of the Orthodox social mission, stronger cooperation between the Church and the state and anti-Western bias. The analysis is based on two cases: the Yekaterinburg Archdioceseβs periodical Β«Orthodox NewspaperΒ» and pravoslavie. ru web portal. The study reveals that the traditionalist media have a number of features. Hybridization of genres is observed: sermons turn to interviews, and spiritual essays are presented as news stories. The media construct a specific Orthodox chronotope. The secular concept of relevance as constant change of agenda is substituted for the cyclicity of the church life: the most important events are related to religious feasts. The structure of religious institution is projected on media discourse: the Β«Orthodox NewspaperΒ» and Pravoslovie.ru range the topics and the authors according to hierarchy principle, inherent in the off-line Orthodoxy. Thus, the traditionalist Orthodox media adapt print and online periodicals for the intergroup communications and needs constructing their own media content. Β© 2018 Russian Public Opinion Research Center VCIOM. All Rights Reserved.Π ΠΎΡΡΠΈΠΉΡΠΊΠΈΠΉ Π€ΠΎΠ½Π΄ Π€ΡΠ½Π΄Π°ΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ
ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ (Π Π€Π€Π): 16-03-00387Keywords: mediatization, Orthodoxy, traditionalism, media, religious identity Acknowledgment. The study is funded by Russian Foundation for Basic Research (project no. 16-03-00387)
ΠΠ΅Π΄ΠΈΠ°ΡΠΈΠ·Π°ΡΠΈΡ ΠΏΡΠ°Π²ΠΎΡΠ»Π°Π²ΠΈΡ: Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΡΠΈΡ ΠΎΠ΄ΠΎΠ² Π ΠΠ¦ Π² ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΡ ΠΌΠ΅Π΄ΠΈΠ°
ΠΡΠ°Π²ΠΎΡΠ»Π°Π²Π½ΡΠ΅ ΠΏΡΠΈΡ
ΠΎΠ΄Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΡΡ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΠ΅ ΠΌΠ΅Π΄ΠΈΠ° Π΄Π»Ρ ΠΌΠΈΡΡΠΈΠΎΠ½Π΅ΡΡΠΊΠΈΡ
ΠΈ Π²Π½ΡΡΡΠ΅Π½Π½ΠΈΡ
ΡΠ΅Π»Π΅ΠΉ. Π ΡΡΠ°ΡΡΠ΅ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΡΠ΅ΡΡΡ, ΠΊΠ°ΠΊ ΡΠ°Π±ΠΎΡΠ° Ρ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΌΠ΅Π΄ΠΈΠ° Π²Π»ΠΈΡΠ΅Ρ Π½Π° ΠΏΠΎΠ·ΠΈΡΠΈΡ ΠΏΡΠΈΡ
ΠΎΠΆΠ°Π½ Π² ΡΠ΅Π»ΠΈΠ³ΠΈΠΎΠ·Π½ΠΎΠΉ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ. ΠΠ½Π°Π»ΠΈΠ· ΠΎΡΠ½ΠΎΠ²Π°Π½ Π½Π° ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ Π΄Π²ΡΡ
ΠΏΡΠ°Π²ΠΎΡΠ»Π°Π²Π½ΡΡ
ΠΏΡΠΈΡ
ΠΎΠ΄ΠΎΠ² ΠΠΊΠ°ΡΠ΅ΡΠΈΠ½Π±ΡΡΠ³Π°: ΠΈΡ
ΡΠ°ΠΌΠΎΠΏΡΠ΅Π·Π΅Π½ΡΠ°ΡΠΈΠΈ Π² ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΡ
ΠΌΠ΅Π΄ΠΈΠ° ΠΈ ΠΏΡΠ°ΠΊΡΠΈΠΊ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π° ΠΊΠΎΠ½ΡΠ΅Π½ΡΠ°. ΠΠ²ΡΠΎΡΡ ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡ, ΡΡΠΎ Π΄ΠΈΡΠΊΡΡΡ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΡ
ΠΌΠ΅Π΄ΠΈΠ° Π½Π΅ Π½Π°Π΄Π΅Π»ΡΠ΅Ρ ΠΏΡΠΈΡ
ΠΎΠΆΠ°Π½ Π°Π³Π΅Π½ΡΠΈΠ²Π½ΠΎΡΡΡΡ. Π ΡΠΎ ΠΆΠ΅ Π²ΡΠ΅ΠΌΡ ΡΠ°Π±ΠΎΡΠ° Ρ ΠΌΠ΅Π΄ΠΈΠ° ΠΏΠΎΠ²ΡΡΠ°Π΅Ρ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΠΉ ΠΊΠ°ΠΏΠΈΡΠ°Π» ΠΏΡΠΈΡ
ΠΎΠΆΠ°Π½ Π² ΡΠ°ΠΌΠΊΠ°Ρ
ΠΠΊΠ°ΡΠ΅ΡΠΈΠ½Π±ΡΡΠ³ΡΠΊΠΎΠΉ Π΅ΠΏΠ°ΡΡ
ΠΈΠΈ. ΠΠ»Ρ ΡΠ²ΡΡΠ΅Π½Π½ΠΈΠΊΠΎΠ² ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΌΠ΅Π΄ΠΈΠ° ΠΈΠΌΠ΅Π΅Ρ Π½Π΅ΠΎΠ΄Π½ΠΎΠ·Π½Π°ΡΠ½ΡΠ΅ ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΡ: ΡΡΠΈΠ»ΠΈΠ²Π°Ρ ΠΈΡ
ΡΠΏΠΈΡΡΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π²ΡΠΎΡΠΈΡΠ΅Ρ, ΠΎΠ½ΠΎ ΡΠ°ΠΊΠΆΠ΅ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ ΠΏΠ΅ΡΠ΅ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ Π½Π°Π΄ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²ΠΎΠΌ ΠΊΠΎΠ½ΡΠ΅Π½ΡΠ° ΠΌΠ΅ΠΆΠ΄Ρ ΡΠ²ΡΡΠ΅Π½Π½ΠΈΠΊΠ°ΠΌΠΈ ΠΈ ΠΌΠ΅Π΄ΠΈΠ°ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»Π°ΠΌΠΈ.Orthodox parishes actively use social media for their missionary and inner purposes. The paper analyses how the work with social media affect the position of parish members in the religious organization. The analysis is based on comparison of two Yekaterinburg Orthodox parishes: their self-presentation in social media and practices of content production. The authors show that social media discourse does not endow parishioners with agency, at the same time, the media production activities increase the social capital of Orthodox media creatives within Yekaterinburg Diocese. For the priests the media usage has ambiguous consequences: it reinforces the epistemic authority and leads to reassignment of controlling functions over content production between priests and parish media professionals.This work was supported by the Russian Foundation for Basic Research under grant Social media as a transforming agent of Russian Orthodoxy, number 19-011-00871
Experience in the treatment of psoriasis patients using Apremilast, a selective signalling pathway inhibitor
The article presents a brief description of Πpremilast β the target synthetic anti-inflammatory drug, which is representative of a new class of agents for the treatment of psoriasis and psoriatic arthritis. The efficiency and safety of the new drug in the treatment of patients with severe psoriasis are shown
Holding it together: rapid evolution and positive selection in the synaptonemal complex of Drosophila
Background
The synaptonemal complex (SC) is a highly conserved meiotic structure that functions to pair homologs and facilitate meiotic recombination in most eukaryotes. Five Drosophila SC proteins have been identified and localized within the complex: C(3)G, C(2)M, CONA, ORD, and the newly identified Corolla. The SC is required for meiotic recombination in Drosophila and absence of these proteins leads to reduced crossing over and chromosomal nondisjunction. Despite the conserved nature of the SC and the key role that these five proteins have in meiosis in D. melanogaster, they display little apparent sequence conservation outside the genus. To identify factors that explain this lack of apparent conservation, we performed a molecular evolutionary analysis of these genes across the Drosophila genus.
Results
For the five SC components, gene sequence similarity declines rapidly with increasing phylogenetic distance and only ORD and C(2)M are identifiable outside of the Drosophila genus. SC gene sequences have a higher dN/dS (Ο) rate ratio than the genome wide average and this can in part be explained by the action of positive selection in almost every SC component. Across the genus, there is significant variation in Ο for each protein. It further appears that Ο estimates for the five SC components are in accordance with their physical position within the SC. Components interacting with chromatin evolve slowest and components comprising the central elements evolve the most rapidly. Finally, using population genetic approaches, we demonstrate that positive selection on SC components is ongoing.
Conclusions
SC components within Drosophila show little apparent sequence homology to those identified in other model organisms due to their rapid evolution. We propose that the Drosophila SC is evolving rapidly due to two combined effects. First, we propose that a high rate of evolution can be partly explained by low purifying selection on protein components whose function is to simply hold chromosomes together. We also propose that positive selection in the SC is driven by its sex-specificity combined with its role in facilitating both recombination and centromere clustering in the face of recurrent bouts of drive in female meiosis
ΠΠ΅ΡΠ°ΡΠΎΡΠΈΡΠ½ΠΎΡΡΡ Ρ ΡΠ΄ΠΎΠΆΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·Π°: ΠΊΡΠ»ΡΡΡΡΠ½Π°Ρ ΠΏΠ°ΠΌΡΡΡ ΠΈ ΠΏΠ΅ΡΠ΅Π²ΠΎΠ΄
The article presents a complementary semantic-semiotic analysis of an artistic image in the framework of a literary text. The analysis is followed by post-translation descriptions. Being generated and functioning within a literary text an artistic image is considered to be an extended metaphoric formation primarily destined to fulfill the aesthetic function. Particular attention is paid to the cultural information and memory embodied in a unique cultural code presented in an artistic image and closely connected with its metaphoric characteristics. The present research was conducted on the material of the βstrongβ text of the Russian culture β βThe Master and Margaritaβ by M. Bulgakov. The artistic image of Bulgakovβs tom-cat Behemoth is a heterogeneous metaphoric formation combining the cultural memory of a Biblical monster Behemoth, zoo-metaphorical characteristics of a hippopotamus (as a real fauna representative) and various connotations of a black tom-cat in its real and mythological hypostases. The research methodology assumes integrated analysis combining mythopoetic, hermeneutic and comparative methods. In the situation of literary translation, a literary image can be considered as a regular unit of translation, the reconstruction of which in βotherβ languages and cultures requires special translatorβs decisions and application of effective translation techniques and strategies
THE ROLE OF INDIVIDUAL HUMAN POTENTIAL IN THE SPACE OF THE UNIVERSAL ONE
In the understanding of the present paperβs authors the individual human potential (IHP) is considered as upbringing, education, health, talent, skills and abilities that are directly inherent of a person. IHP is fully disclosed in the space of human capital and is an element of the universal potential. In the human life cycle the IHP changes daily and resembles the change in stock quotes of companies on the stock exchange. Each day it can increase and decrease depending on the inspiration, physical and psychological health, and its level changes in the context of education and knowledge received at the moment. In the time aspect the IHP is limited by the life cycle of a person and can have various trends β continuously increasing, stabilizing, decreasing, and abruptly changing (a sharp increase or decrease). The continuously increasing trend is mainly provided by education accompanied with a stabilizing health factor. The second (stabilizing one) implies the lack of a personβs desire to increase his/her IHP or the limitation of external factors. The third (decreasing one) may be associated with a gradual loss of mental or psychological health or the gradual influence of the environment. The last trend (abruptly changing one) is associated with a sharp increase in its capabilities. This is either a transition to another level of education or a sharp change in the surrounding socio-economic paradigm (i.e., the possibility of using a larger amount of human capital). Changes to the IHP may have limitations caused by the external reasons such as: legislative, moral, ethical, political, ethnic, etc. Despite the fact that IHP has a limited life cycle, the human potential (capital) increases in time perspective primarily due to the increase of the accumulated by the mankind knowledge, skills and abilities, as well as due to the constant population increase. The paper deals with the issue of the essential difference between the universal human potential and human capital. It is proved that the human potential can change abruptly, which can be caused by epoch-making discoveries and inventions, socio-economic, political changes, as well as environmental disasters. In contrast to the potential, the accumulated universal capital changes from the abovementioned reasons, i.e. it must take some time for the potential to pass into the capital. The main engine of this transition is the individual human potential. The paper deals with the formation of the structure of human potential and capital. It is shown that the structure is of discrete nature and is formed by merging and combining IHP in various industrial, social, national and supranational forms to achieve certain results and achievements (industrial, social, political, scientific, etc.). The paper also presents the results of research on the formation of IHP in high school students of the Arctic zone of Eastern Siberia living in locally isolated settlements, as well as the abrupt change in their IHP at a sharp change in socio-economic conditions. The results of their adaptation are demonstrated
Sustained-release calcium antagonist in patients over 60 years with isolated and systolo-diastolic arterial hypertension
Aim. To study antihypertensive and organo-protective effects of a calcium antagonist (CA), controlled-release (CR) nifedipine, in patients over 60 years with Stage I-II isolated systolic and systolo-diastolic arterial hypertension (ISAH, SDAH).Material and methods. This 24-week open prospective study included 48 patients aged over 60 years with Stage I-II AH. SDAH and ISAH participants received nifedipine SR in the dose of 40 mg/d. Treatment effectiveness was assessed by dynamics of office blood pressure (BP) and 24-hour BP monitoring (BBP) parameters. Organoprotective effect was assessed by dynamics of echocardiography parameters and microalbuminuria (MAU) levels.Results. Nifedipine SR therapy was associated with substantial BP reduction and improved circadian BP profile in all participants; reduced myocardial hypertrophy in elderly people; normalisation of left ventricular (LV) diastolic function and decreased number of patients with MAU in both groups, especially among those with ISAH.Conclusion. Complex assessment of nifedipine SR clinical effectiveness in ISAH and SDAH patients aged over 60 years demonstrated multiple effects on AH-related parameters and improved circulatory functioning in elderly patients. Nifedipine SR is a medication of choice in ISAH patients