13 research outputs found
Optimal Occulter Design for Finding Extrasolar Planets
One proposed method for finding terrestrial planets around nearby stars is to
use two spacecraft--a telescope and a specially shaped occulter that is
specifically designed to prevent all but a tiny fraction of the starlight from
diffracting into the telescope. As the cost and observing cadence for such a
mission will be driven largely by the separation between the two spacecraft, it
is critically important to design an occulter that can meet the observing goals
while flying as close to the telescope as possible. In this paper, we explore
this tradeoff between separation and occulter diameter. More specifically, we
present a method for designing the shape of the outer edge of an occulter that
is as small as possible and gives a shadow that is deep enough and large enough
for a 4m telescope to survey the habitable zones of many stars for Earth-like
planets. In particular, we show that in order for a 4m telescope to detect in
broadband visible light a planet 0.06 arcseconds from a star shining
times brighter than the planet requires a specially-shaped occulter 50m in
diameter positioned about km in front of the telescope.Comment: 14 pages, 4 figures, 15 subfigure
Fast Linearized Coronagraph Optimizer (FALCO) IV. Coronagraph design survey for obstructed and segmented apertures
Coronagraph instruments on future space telescopes will enable the direct detection and characterization of Earth-like exoplanets around Sun-like stars for the first time. The quest for the optimal optical coronagraph designs has made rapid progress in recent years thanks to the Segmented Coronagraph Design and Analysis (SCDA) initiative led by the Exoplanet Exploration Program at NASA's Jet Propulsion Laboratory. As a result, several types of high-performance designs have emerged that make use of dual deformable mirrors to (1) correct for optical aberrations and (2) suppress diffracted starlight from obstructions and discontinuities in the telescope pupil. However, the algorithms used to compute the optimal deformable mirror surface tend to be computationally intensive, prohibiting large scale design surveys. Here, we utilize the Fast Linearized Coronagraph Optimizer (FALCO), a tool that allows for rapid optimization of deformable mirror shapes, to explore trade-offs in coronagraph designs for obstructed and segmented space telescopes. We compare designs for representative shaped pupil Lyot and vortex coronagraphs, two of the most promising concepts for the LUVOIR space mission concept. We analyze the optical performance of each design, including their throughput and ability to passively suppress light from partially resolved stars in the presence of low-order aberrations. Our main result is that deformable mirror based apodization can suffciently suppress diffraction from support struts and inter-segment gaps whose widths are on the order of ~0.1% of the primary mirror diameter to detect Earth-sized planets within a few tens of milliarcseconds from the star
Evidence of Transmission of Plasmodium vivax 210 and Plasmodium vivax 247 by Anopheles gambiae and An. coluzzii, Major Malaria Vectors in Benin/West Africa
Current diagnostic and surveillance systems in Benin are not designed to accurately identify or report non-Plasmodium falciparum (Pf) human malaria infections. This study aims to assess and compare the prevalence of circumsporozoite protein (CSP) antibodies of Pf and P. vivax (Pv) in Anopheles gambiae s.l. in Benin. For that, mosquito collections were performed through human landing catches (HLC) and pyrethrum spray catches (PSC). The collected mosquitoes were morphologically identified, and Pf, Pv 210, and Pv 247 CSP antibodies were sought in An. gambiae s.l. through the ELISA and polymerase chain reaction (PCR) techniques. Of the 32,773 collected mosquitoes, 20.9% were An. gambiae s.l., 3.9% An. funestus gr., and 0.6% An. nili gr. In An. gambiae s.l., the sporozoite rate was 2.6% (95% CI: 2.1-3.1) for Pf, against 0.30% (95% CI: 0.1-0.5) and 0.2% (95% CI: 0.1-0.4), respectively, for Pv 210 and Pv 247. P. falciparum sporozoite positive mosquitoes were mostly An. gambiae (64.35%), followed by An. coluzzii (34.78%) and An. arabiensis (0.86%). At the opposite, for the Pv 210 sporozoite-positive mosquitoes, An. coluzzii and An. gambiae accounted for 76.92% and 23.08%, respectively. Overall, the present study shows that P. falciparum is not the only Plasmodium species involved in malaria cases in Benin
Dynamics of insecticide resistance in malaria vectors in Benin: first evidence of the presence of L1014S kdr mutation in Anopheles gambiae from West Africa
<p>Abstract</p> <p>Background</p> <p>Insecticide resistance monitoring is essential to help national programmers to implement more effective and sustainable malaria control strategies in endemic countries. This study reported the spatial and seasonal variations of insecticide resistance in malaria vectors in Benin, West Africa.</p> <p>Methods</p> <p><it>Anopheles gambiae s.l </it>populations were collected from October 2008 to June 2010 in four sites selected on the basis of different use of insecticides and environment. WHO susceptibility tests were carried out to detect resistance to DDT, fenitrothion, bendiocarb, permethrin and deltamethrin. The synergist piperonyl butoxide was used to assess the role of non-target site mechanisms in pyrethroid resistance. <it>Anopheles gambiae </it>mosquitoes were identified to species and to molecular M and S forms using PCR techniques. Molecular and biochemical assays were carried out to determine <it>kdr </it>and <it>Ace.1<sup>R </sup></it>allelic frequencies and activity of the detoxification enzymes.</p> <p>Results</p> <p>Throughout the surveys very high levels of mortality to bendiocarb and fenitrothion were observed in <it>An. gambiae s.l</it>. populations. However, high frequencies of resistance to DDT and pyrethroids were seen in both M and S form of <it>An. gambiae s.s</it>. and <it>Anopheles arabiensis</it>. PBO increased the toxicity of permethrin and restored almost full susceptibility to deltamethrin. <it>Anopheles gambiae s.l</it>. mosquitoes from Cotonou and Malanville showed higher oxidase activity compared to the Kisumu susceptible strain in 2009, whereas the esterase activity was higher in the mosquitoes from Bohicon in both 2008 and 2009. A high frequency of <it>1014F kdr </it>allele was initially showed in <it>An. gambiae </it>from Cotonou and Tori-Bossito whereas it increased in mosquitoes from Bohicon and Malanville during the second year. For the first time the <it>L1014S kdr </it>mutation was found in <it>An. arabiensis </it>in Benin. The <it>ace.1<sup>R </sup></it>mutation was almost absent <it>in An. gambiae s.l</it>.</p> <p>Conclusion</p> <p>Pyrethroid and DDT resistance is widespread in malaria vector in Benin and both metabolic and target site resistance are implicated. Resistance was not correlated with a change of malaria species and/or molecular forms. The <it>1014S kdr </it>allele was first identified in wild population of <it>An. arabiensis </it>hence confirming the expansion of pyrethroid resistance alleles in Africa.</p
Time-Frequency Characterization of Femtosecond Extreme Ultraviolet Pulses
A measurement of chirp and pulse duration of fifth harmonic of a frequency-doubled Ti:sapphire laser was presented. The photoelectron signal due to cross correlation of harmonics generated by 400 nm blue light and an 800 nm infrared probe pulse, was measured using energy resolved cross-correlation method. Results demonstrated that the technique could be used to characterize the time-frequency behavior of much higher-order harmonics
Rigorous analysis of light diffraction ellipsometry by striated muscle fibers.
A rigorous analysis of both the transverse electric and the transverse magnetic modes of light diffracted from a muscle fiber is performed. From the expressions of electromagnetic field components, ellipsometry parameters, differential field ratio, r, and birefringence, delta n, have been obtained. A theoretical formulation that introduces myofibril skew planes and a randomization factor about the average skew plane yields a relationship that shows good fit to experimental data of Chen et al. (Biophys. J. 56:595, 1989) and Burton et al. (J. Muscle Res. Cell Motil. 11:258, 1990). Using indices of refraction within each of the regions of the sarcomeric unit that are consistent with our knowledge of the molecular structure of the sarcomere in the analysis, it is shown that the transition from the rigor state to the resting state leads to as much as a approximately 13% decrease in the r-value and an equally significant change in delta n
Optical Dispersion Properties of Tricyanovinylaniline Polymer Thin Films for Ultrashort Optical Pulse Diagnostics
We have investigated a series of tricyanovinylaniline (TCV) polymer thin films for their use in ultrashort optical pulse (USP) diagnostics of femto second Ti:Sapphire lasers. These thin films are ideally suited for USP diagnostics since they eliminate the angle tuning associated with birefringent phase-matched crystals, minimize pulse distortion introduced by group velocity dispersion, and exhibit excellent photochemical stability. The linear optical dispersion of these polymers can be tailored over a wide range for efficient and distortionless frequency conversion. Coherence lengths between 420 nm and 54 microns at a wavelength λ = 800 nm have been found for the two extreme cases of dispersion in these materials. Film thicknesses of at least two microns are tolerable without introducing any significant pulse distortion at the same wavelength (λ = 800 nm)
Optical Dispersion Properties of Tricyanovinylaniline Polymer Thin Films for Ultrashort Optical Pulse Diagnostics
We have investigated a series of tricyanovinylaniline (TCV) polymer thin films for their use in ultrashort optical pulse (USP) diagnostics of femto second Ti:Sapphire lasers. These thin films are ideally suited for USP diagnostics since they eliminate the angle tuning associated with birefringent phase-matched crystals, minimize pulse distortion introduced by group velocity dispersion, and exhibit excellent photochemical stability. The linear optical dispersion of these polymers can be tailored over a wide range for efficient and distortionless frequency conversion. Coherence lengths between 420 nm and 54 microns at a wavelength λ = 800 nm have been found for the two extreme cases of dispersion in these materials. Film thicknesses of at least two microns are tolerable without introducing any significant pulse distortion at the same wavelength (λ = 800 nm)