Employment of activity-based costing in the process of company business model generation

This paper presents a method of presentation of information for the purposes of managerial decision making in terms of activity-based accounting method and company business model generation. Availability of concerted control strategy and disclosure of a business model in organization's reporting will enable to meet demands of all types of users of information on activity of a company. We offer employment of appraisal of a company value in terms of use of Activity-Based Costing

TO THE QUESTION OF PREPARATION OF WORKERS IN THE CONDITIONS OF INDUSTRIAL PRODUCTION

В статье рассматриваются актуальность разработки содержательных компонентов подготовки рабочих в условиях промышленного производства, актуальность применения имитационных технологий обученияThe article discusses the relevance of the development of substantial components of the training of workers in industrial production, the relevance of the use of simulation training technologie

The effect of radiofrequency modulation of 57Fe hyperfine interaction by rotating magnetic field

The effect of 57Fe hyperfine interaction radiofrequency (rf) modulation by external rotating magnetic field was studied in thin Permalloy foil by means of Mössbauer spectroscopy. The rf effect was investigated as a function of intensity for several rf field frequencies. The experiments show that the external rotating rf field causes considerable changes in the hyperfine pattern. The obtained spectra are in disagreement with those obtained by Perlow [Phys. Rev. 172 (1968) 319]. They also are inconsistent with magnetostriction hypothesis. Proceeding from the Mössbauer spectrum analysis one may conclude that the magnetization of investigated foil changes its direction in a complex manner. However, the undertaken experiments show that the essential number of Mössbauer nuclei experience the rotating magnetic field influence

Optical spectra, crystal-field parameters, and magnetic susceptibility of the new multiferroic NdFe3(BO3)4

We report high-resolution optical absorption spectra for NdFe3(BO3)4 trigonal single crystal which is known to exhibit a giant magnetoelectric effect below the temperature of magnetic ordering TN = 33 K. The analysis of the temperature-dependent polarized spectra reveals the energies and, in some cases, symmetries and exchange splittings of Nd3+ 84 Kramers doublets. We perform crystal-field calculations starting from the exchange-charge model, obtain a set of six real crystal-field parameters, and calculate wave functions and magnetic g-factors. In particular, the values g(perpendicular) = 2.385, g(parallel) = 1.376 were found for the Nd3+ ground-state doublet. We obtain Bloc=7.88 T and |JFN|= 0.48 K for the values of the local effective magnetic field at liquid helium temperatures at the Nd3+ site and the Nd - Fe exchange integral, respectively, using the experimentally measured Nd3+ ground-state splitting of 8.8 cm-1. To check reliability of our set of crystal field parameters we model the magnetic susceptibility data from literature. A dimer containing two nearest-neighbor iron ions in the spiral chain is considered to partly account for quasi-one-dimensional properties of iron borates, and then the mean-field approximation is used. The results of calculations with the exchange parameters for Fe3+ ions Jnn = -6.25 K (intra-chain interactions) and Jnnn = -1.92 K (inter-chain interactions) obtained from fitting agree well with the experimental data.Comment: 13 pages, 8 figures, 2 table

MODEL OF THE PROCESS OF ADDITIONAL PROFESSIONAL TRAINING OF WORKERS IN THE CONDITIONS OF THE INDUSTRIAL ENTERPRISE

В статье представлена разработка модели процесса дополнительной профессиональной подготовки рабочих в условиях промышленного предприятияThe article presents the development of a model for the process of additional professional training of workers in an industrial enterpris

PEDAGOGICAL TECHNOLOGIES IN THE ORGANIZATION OF ADDITIONAL PROFESSIONAL TRAINING OF WORKERS IN AN INDUSTRIAL ENTERPRISE

В статье рассматриваются возможности применения элементов современных педагогических технологий в процессе подготовки рабочих кадров в условиях промышленного предприятияThe article considers the possibilities of applying elements of modern pedagogical technologies in the process of training workers in an industrial enterpris

Mononuclear subsets and cytokine profile of venous and capillary blood in patients with psoriasis and healthy people

Psoriasis is considered an autoimmune disease with a predominantly cellular mechanism for the development of disorder. Studies in immune pathogenesis of psoriasis were performed either in animal model, which is not just similar to humans, or the data were obtained in patients by means of skin window method, which is traumatic, or by examining venous blood. However, it is difficult to discern parameters of the local immune response in venous blood samples. We have attempted to find an adequate method which would be convenient both for the patient and for the researcher, in order to assess local immune processes occurring in the skin affected by psoriasis. We examined 20 patients with a verified diagnosis of psoriasis, the average age was 44.3 years. The control group included 15 healthy adults, with average age of 46.6 years. Capillary blood was taken by fingerprick, whereas, in psoriatic patients, the samples were taken near the psoriatic lesion at a final volume of 400 μL in two microvettes. Venous blood (3 mL) was taken from the cubital vein into a vacuum tube with EDTA. Clinical analysis of venous and capillary blood was performed in automated hematological analyzer. Immunophenotyping was performed by four-color staining of whole capillary and venous blood followed by lysis of erythrocytes. Cytofluorometry was performed using techniques and reagents from BD Biosciences (USA). Plasma cytokines were determined by multiplex approach (MagPix, BioRad, USA). Upon clinical analysis of blood, the difference between capillary and venous blood was not found, either in healthy group, or among patients with psoriasis. In healthy people, the subsets of mononuclear cells, did not differ between venous and capillary blood. The samples of capillary and venous blood in the patients with psoriasis showed significantly increased levels of double-positive lymphocytes (CD45RA+/CD45R0+), B lymphocytes and NKT lymphocytes (both for relative and and absolute values). A significant increase in the percentage of naive T lymphocytes, activated helpers (Thact) and Treg, as well as B1 cells and Breg, and a significant decrease in B2 lymphocytes was registered in capillary blood of the patients with psoriasis. In venous blood samples from psoriatic patients, only a significant increase in Thact, Treg, and Breg was revealed. In the capillary blood of patients with psoriasis, we found a significant increase in the levels of non-classical M2 monocytes and inflammatory Minfl monocytes, and a decrease in classical M1 monocyte levels; in venous blood of psoriatic patients, only an increase in inflammatory Minfl monocytes was revealed. In capillary blood, all the studied cytokines in psoriasis patients significantly exceeded the levels of corresponding cytokines in healthy controls, except of IL-10. The levels of this cytokine did not differ from healthy group. In venous blood, the levels of most studied cytokines in the group of patients with psoriasis did not differ from the group of healthy ones. Approximately two-fold increase was revealed for IL-4, IL-21, IL-23 and TNF. First, the subsets of mononuclear cells and the cytokine profile of capillary and venous blood of healthy people did not differ significantly. Secondly, our proposed method for determining the subsets of mononuclear cells and capillary blood cytokines profile from the area of psoriatic lesions may be used to monitor local immunity in the patients with psoriasis. This approach is significantly less traumatic than the skin window method and more informative than the studies of venous blood

Weighted ergodic theorems for Banach-Kantorovich lattice Lp(∇^,μ^)L_{p}(\hat{\nabla},\hat{\mu})

In the present paper we prove weighted ergodic theorems and multiparameter weighted ergodic theorems for positive contractions acting on $L_p(\hat{\nabla},\hat{\mu})$. Our main tool is the use of methods of measurable bundles of Banach-Kantorovich lattices.Comment: 11 page

Dynamics of T helper subpopulations in the critical period of severe injury in children

Severe mechanical injury is one of the main reasons behind children’s disability and mortality. Severe injury induces a complex host immune response to tissue injury, a parallel pro- and anti-inflammatory state, bearing an elevated risk for infectious complications (IC) and/or multiple organ failure (MOF). This study aimed to determine the informative immunological criteria of traumatic injury severity and prognosis outcome in children (severe injury group (SInj, ISS ≥ 16), n = 87; mild/moderate injury group (MInj, ISS < 16), n = 34) based on the assessment of absolute cell count (abs) and percentage of such T helper subpopulations as regulatory T lymphocytes – CD4+CD127lowCD25high(Treg), Th17 lymphocytes – CD4+CD161+ and CD4+CD127higtCD25high T cells(T127hi) in severe injury cases grouped by the outcome (favorable, n = 47; unfavorable, n = 40) and depending on IC (n = 16) and the development of MOF (n = 11) on the 1st, 3d , 5th, 7th, 14th day after injury. The control group was comprised of 80 apparently healthy children comparable in age and sex. An inverse relationship between severity of injury, degree of blood loss and outcome of injury was revealed with the abs of all Th populations, but for Th abs and Treg abs the most significant correlation was found (Spearman’s R ≤ -0,70, p < 0.00001). For SInj group, a pronounced decrease of Th abs, Treg abs, T127hi abs and Th17 abs, in the acute post-traumatic period with an increase to 14 days was revealed. The values of in the first day for indicators of patients with MInj group correspond to the values of control group and significantly differ from SInj group. There are different kinetics of percentage Th subpopulations in peripheral blood of children with severe injuries. The Th17%CD4+ and T127hi%CD4+ significant increase in 1st-3d  and 3d -7th days after injury respectively in comparation with сontrol and MInj groups. There were no differences between groups in terms of Treg%CD4+. The lower-level Treg abs in trauma patients admitted to the ICU is significantly associated with develop the infectious complications and outcome of trauma. The Th17 abs is significantly reduced in 3-7th days after the injury in the SInj group with MOF. The results of the study indicate that in children levels of Treg, T127hi and Th17 is significantly associated with severity of injury and may be used to predict outcome of trauma and assess the risk of IC and MOF

ПЕРИПРОТЕЗНАЯ (ПЕРИЭКСПЛАНТАТНАЯ) РЕАКЦИЯ ПОСЛЕ РЕКОНСТРУКЦИИ АОРТЫ И АРТЕРИЙ (клиника, диагностика и лечение)

A rare unpredictable serious complication is analyzed: paragraft reaction with formation of perigraft cysts and liquid round the synthetic vessel after reconstructive operations. The etiology and pathogenesis of this uncommon reaction remain unclear and disputable. Perigraft reaction often leads to complications: Infection of the perigraft liquid or cyst with formation of false aneurysms of anastomoses, graft infection with anglogenic sepsis, graft and reconstructed arteries thrombosis because ofextravasal compression, etc. Publications on this problem are scanty. We observed perigraft. reaction in 15 (0,4%) patients after reconstructive operations implanted various grafts. The etiology, pathogenesis, clinical characteristics, prevention, and treatment philosophy in such cases are discussed, based on published reports and our data.В статье анализируется редкое и серьезное осложнение - перипротезнаяреакция, перипротезная серома, периэксплантатная реакция с образованием периэксплантатных кист и жидкости вокруг синтетического заменителя сосуда после реконструктивных операций с применением эксплантатов. Этиология и патогенез этой необычной реакции до сих пор до конца неясны и дискутабельны. Нередко периэксплантатная реакция приводит к различным осложнениям: инфицированию периэксплантатной жидкости или кисты с формированием ложных аневризм анастомозов, инфицированию эксплантата с ангиогенным сепсисом, тромбозу эксплантатов и реконструированных артерий из-за экстравазальной компрессии и т. д. В доступной литературе мало публикаций по этой редкой проблеме. Периэксплантатную реакцию авторы наблюдали у 15 (0,4%) больных после реконструктивных операций с применением различных эксплантатов. В статье обсуждаются этиология, патогенез, клинические особенности, профилактика и лечебные принципы этой патологии по данным литературы и собственного материала