Total Digestible Nutrient of Diet Containing PUFA- Concentrate Supplemented with Yeast and Curcuma Xanthorrhiza Roxb for Dairy Goat

Penelitian ini didisain untuk mengevaluasi kecernaan nutrisi, dinyatakan dalam TDN, dari ransum yang mengandung PUFA konsentrat yang disuplementasi yeast dan Curcuma xanthorrhiza Roxb pada kambing perah. Dua puluh ekor kambing Peranakan Ettawah (PE) pada fase laktasi akhir dialokasikan kedalam 6 perlakuan dengan Rancangan Acak Kelompok. Perlakuan tersebut adalah: PD0: PUFA-diet tanpa suplemen, PDA: dengan Asifit, PDY: dengan 0,5% yeast, PDC: dengan 2% curcuma, dan PDM: dengan 0,5% yeast + 2% curcuma. Ransum- PUFA terdiri atas 80% PUFA- konsentrat sebagai ransum dasar dan 20% rumput gajah. Sumber PUFA terdiri atas jagung giling sangrai, tepung kedelai sangrai, dan minyak jagung. Hasil menunjukkan bahwa konsumsi DM, OM, CP, CF, NFE, ADF, dan GE tidak terpengaruh oleh perlakuan. Namun, EE dan NDF antarperlakuan berbeda signifikan (P<0.05), sedang Ca dan P berbeda sangat signifikan (P<0.01). Kandungan nutrisi yang tinggi (DM, OM, CP, EE, CF, NDF, and GE) ditemukan di feces pada kambing dengan perlakuan Curcuma (PDC), konsekuensinya adalah kecernaan nutrisinya secara signifikan (P<0.05) atau sangat signifikan (P<0.01) terendah. Total digestible nutrient (TDN) dari PDY dan PDM secara signifikan tinggi (79,89% dan 79,37%) disbanding ransum lainnya, terendah pada PDC (69,94%). Hal ini menunjukkan bahwa yeast atau ragi dengan konsentrasi 1,8 108cfu/d baik disuplementasikan tunggal atau dikombinasi dengan 2% Curcuma dapat dikatakan sebagai kandungan yang tepat untuk memperbaiki kecernaan nutrisi pada kambing perah dengan laktasi akhir pada penelitian ini

Total Digestible Nutrient of Diet Containing PUFA- Concentrate Supplemented with Yeast and Curcuma Xanthorrhiza Roxb for Dairy Goat

Penelitian ini didisain untuk mengevaluasi kecernaan nutrisi, dinyatakan dalam TDN, dari ransum yang mengandung PUFA konsentrat yang disuplementasi yeast dan Curcuma xanthorrhiza Roxb pada kambing perah. Dua puluh ekor kambing Peranakan Ettawah (PE) pada fase laktasi akhir dialokasikan kedalam 6 perlakuan dengan Rancangan Acak Kelompok. Perlakuan tersebut adalah: PD0: PUFA-diet tanpa suplemen, PDA: dengan Asifit, PDY: dengan 0,5% yeast, PDC: dengan 2% curcuma, dan PDM: dengan 0,5% yeast + 2% curcuma. Ransum- PUFA terdiri atas 80% PUFA- konsentrat sebagai ransum dasar dan 20% rumput gajah. Sumber PUFA terdiri atas jagung giling sangrai, tepung kedelai sangrai, dan minyak jagung. Hasil menunjukkan bahwa konsumsi DM, OM, CP, CF, NFE, ADF, dan GE tidak terpengaruh oleh perlakuan. Namun, EE dan NDF antarperlakuan berbeda signifikan (P<0.05), sedang Ca dan P berbeda sangat signifikan (P<0.01). Kandungan nutrisi yang tinggi (DM, OM, CP, EE, CF, NDF, and GE) ditemukan di feces pada kambing dengan perlakuan Curcuma (PDC), konsekuensinya adalah kecernaan nutrisinya secara signifikan (P<0.05) atau sangat signifikan (P<0.01) terendah. Total digestible nutrient (TDN) dari PDY dan PDM secara signifikan tinggi (79,89% dan 79,37%) disbanding ransum lainnya, terendah pada PDC (69,94%). Hal ini menunjukkan bahwa yeast atau ragi dengan konsentrasi 1,8 108cfu/d baik disuplementasikan tunggal atau dikombinasi dengan 2% Curcuma dapat dikatakan sebagai kandungan yang tepat untuk memperbaiki kecernaan nutrisi pada kambing perah dengan laktasi akhir pada penelitian ini

Effects of polar cosolvents on cocoa butter extraction using supercritical carbon dioxide

Cocoa butter was successfully extracted from cocoa liquor by supercritical carbondi oxide (SC-CO2) at 35 MPa, 60 oC and 2 mL/min with 5%, 15% and 25% cosolvents. The extraction yield of tryglicerides (TG) and fatty acid (FA) compositions were significantly influenced by the concentration of polar cosolvents. The SC-CO2 extraction efficiency was increased with cosolvent significantly. Ethanol was found to be the best cosolvent for cocoa butter extraction using SC-CO2 followed by isopropanol and acetone. The triglycerides of POP, POS and SOS were contained in the extracted cocoa butter with POS being the major component. Where palmitic, stearic and oleic were the main fatty acids in the cocoa butter samples, with stearic being the highest component. The lower molecular weight (MW) of TGs and FAs showed the higher selectivity compared to the high MW of TGs and FAs. Thus, they were fractionated during the first stage of SC-CO2 process

Growth Process Of Organic Vetiver Root With Potato AS Intercropping Plant

Vetiver oil (Vetiveria zizanoides) is one of Indonesia main export commodities. Vetiver root is perennial plant and generally planted with vegetables as intercropping plant. Increasing the selling price of vetiver oil can be done by transferring the production of conventional vetiver oil (non-organic) to organic vetiver oil. Demonstration of land used was one hectare, which 2,000 m2 for planting vetiver root with potato (Solanum tuberosum) as inter-cropping plant and 8,000 m2 for vetiver root without intercropping, in Sukakarya-Samarang, Garut. The planting used goat and cow dung as manure, distillate water of vetiver oil and liquid bio-pesticide as pesticide. Variables studied included plant height, number of leaf and crotch. In the first quarter of the years, the number of leaf and crotch of vetiver root with intercropping was better than vetiver root without inter-cropping. However, there was not significant difference for plant height of vetiver root, both with and without intercropping. Products of organic potato as intercropping plant of vetiver root were less than those of non-organic potato, but the latter had a better texture and durability

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation

Sebaran Spasial, Kelimpahan dan Struktur Komunitas Zooplankton di Estuari Sungai Siak Serta Faktor-Faktor yang Mempengaruhinya

Penelitian ini bertujuan mengetahui pola sebaran, kelimpahan dan struktur komunitas zooplankton di perairan estuari Sungai Siak. Penelitian dilaksanakan selama tujuh bulan (April-Nopember 2015) dengan jumlah stasiun pengambilan sampel sebanyak 16 titik. Hasil penghitungan dianalisis lebih lanjut untuk mengetahui pola sebaran, jumlah jenis, kelimpahan, indeks keanekaragaman, indeks dominasi dan indeks keseragaman. Hasil analisis data, diperoleh jumlah jenis zooplankton yang ditemukan sebanyak 21 jenis terdiri dari kelompok Crustacea sebanyak 8 jenis, Ciliata sebanyak 11 jenis dan Sarcodina sebanyak 2 jenis. Kelimpahan zooplankton di masing-masing stasiun pengamatan berkisar antara 1.570-38.512 ind/m3. Struktur komunitas zooplankton di muara Sungai Siak ditandai dengan indeks keanekaragaman yang tinggi (>3), keseragaman tinggi dan indek dominansi yang rendah. Terdapat dua jenis zooplankton dominan di estuari Sungai Siak yaitu Tintinnopsis radix dan Leprotintinnus nordgvisti masing-masing ditemukan pada November dan Juni. Kelimpahan zooplankton dipengaruhi tingkat kecerahan perairan. Pada saat kecerahan rendah, jumlah jenis zooplankton di perairan ini sangat rendah. Secara umum, kondisi lingkungan perairan estuari Sungai Siak masih mendukung kehidupan zooplankton