Research in Natural Laminar Flow and Laminar-Flow Control, part 2

Part 2 of the Symposium proceedings includes papers addressing various topics in basic wind tunnel research/techniques and computational transitional research. Specific topics include: advanced measurement techniques; laminar flow control; Tollmien-Schlichting wave characteristics; boundary layer transition; flow visualization; wind tunnel tests; flight tests; boundary layer equations; swept wings; and skin friction

Research in Natural Laminar Flow and Laminar-Flow Control, part 3

Part 3 of the Symposium proceedings contains papers addressing advanced airfoil development, flight research experiments, and supersonic transition/laminar flow control research. Specific topics include the design and testing of natural laminar flow (NLF) airfoils, NLF wing gloves, and NLF nacelles; laminar boundary-layer stability over fuselage forebodies; the design of low noise supersonic/hypersonic wind tunnels; and boundary layer instability mechanisms on swept leading edges at supersonic speeds

Research in Natural Laminar Flow and Laminar-Flow Control, part 1

Since the mid 1970's, NASA, industry, and universities have worked together to conduct important research focused at developing laminar flow technology that could reduce fuel consumption for general aviation, commuter, and transport aircraft by as much as 40 to 50 percent. The symposium was planned in view of the recent accomplishments within the areas of laminar flow control and natural laminar flow, and the potential benefits of laminar flow technology to the civil and military aircraft communities in the United States. Included were technical sessions on advanced theory and design tool development; wind tunnel and flight research; transition measurement and detection techniques; low and high Reynolds number research; and subsonic and supersonic research

Craniofacial Secular Change in Recent Mexican Migrants

Research by economists suggests that recent Mexican migrants are better educated and have higher socioeconomic status (SES) than previous migrants. Because factors associated with higher SES and improved education can lead to positive secular changes in overall body form, secular changes in the craniofacial complex were analyzed within a recent migrant group from Mexico. The Mexican group represents individuals in the act of migration, not yet influenced by the American environment, and thus can serve as a starting point for future studies of secular change in this population group. The excavation of a historic Hispanic cemetery in Tucson, Arizona, also allows for a comparison between historic Hispanics and recent migrants to explore craniofacial trends over a broad time period, as both groups originate from Mexico. The present research addresses two main questions: (1) Are cranial secular changes evident in recent Mexican migrants? (2) Are historic Hispanics and recent Mexican migrants similar? By studying secular changes within a migrant population group, secular trends may be detected, which will be important for understanding the biological variation of the migrants themselves and will serve as a preliminary investigation of secular change within Mexican migrants. The comparison of a sample of recent Mexican migrants with a historic Hispanic sample, predominantly of Mexican origin, allows us to explore morphological similarities and differences between early and recent Mexicans within the United States. Vault and face size and a total of 82 craniofacial interlandmark distances were used to explore secular changes within the recent Mexican migrants (females, n = 38; males, n = 178) and to explore the morphological similarities between historic Hispanics (females, n = 54; males, n = 58) and recent migrants. Sexes were separated, and multivariate adaptive regression splines and basis splines (quadratic with one knot) were used to assess the direction and magnitude of secular trends for the recent Mexican migrants. Because dates of birth were unavailable for the historic sample, partial least squares discriminant analysis (PLS-DA) was used to evaluate morphological differences between historic and recent Mexican migrant samples. The data were separated into a training data set and a testing data set to ensure realistic results. Males had eight variables (four positive and four negative) and females had six variables (two positive and four negative) that demonstrated significant differences over time. In the PLS-DA, three components were identified as important in model creation and resulted in a classification accuracy of 87% when applied to a testing sample. The high classification accuracy demonstrates significant morphological differences between the two groups, with the historic Hispanic sample displaying overall larger craniofacial dimensions. While differences in cranial morphology are evident between historic Hispanics and recent Mexican migrants, relatively few positive and negative secular trends were detected within the recent migrant sample

Benchmarking Technology-Based Entrepreneurship in the Charleston Region

A study of resources and opportunities for technology-based economic development in Charleston, South Carolina. The study draws on interviews and a survey of managers of technology-intensive enterprises and public-sector institutions in the Charleston area conducted in June 1996.IC2 Institut

On the acoustic diffraction by the edges of benthic shells

Author Posting. © Acoustical Society of America, 2004. This article is posted here by permission of Acoustical Society of America for personal use, not for redistribution. The definitive version was published in Journal of the Acoustical Society of America 116 (2004): 239-244, doi:10.1121/1.1675813.Recent laboratory measurements of acoustic backscattering by individual benthic shells have isolated the edge-diffracted echo from echoes due to the surface of the main body of the shell. The data indicate that the echo near broadside incidence is generally the strongest for all orientations and is due principally to the surface of the main body. At angles well away from broadside, the echo levels are lower and are due primarily to the diffraction from the edge of the shell. The decrease in echo levels from broadside incidence to well off broadside is shown to be reasonably consistent with the decrease in acoustic backscattering from normal incidence to well off normal incidence by a shell-covered seafloor. The results suggest the importance of the edge of the shell in off-normal-incidence backscattering by a shell-covered seafloor. Furthermore, when considering bistatic diffraction by edges, there are implications that the edge of the shell (lying on the seafloor) can cause significant scattering in many directions, including at subcritical angles.This research was supported by the U.S. Office of Naval Research (Grant No. N00014-02-1-0095) and the Woods Hole Oceanographic Institution (WHOI), Woods Hole, MA

The genetic basis for adaptation of model-designed syntrophic co-cultures.

Understanding the fundamental characteristics of microbial communities could have far reaching implications for human health and applied biotechnology. Despite this, much is still unknown regarding the genetic basis and evolutionary strategies underlying the formation of viable synthetic communities. By pairing auxotrophic mutants in co-culture, it has been demonstrated that viable nascent E. coli communities can be established where the mutant strains are metabolically coupled. A novel algorithm, OptAux, was constructed to design 61 unique multi-knockout E. coli auxotrophic strains that require significant metabolite uptake to grow. These predicted knockouts included a diverse set of novel non-specific auxotrophs that result from inhibition of major biosynthetic subsystems. Three OptAux predicted non-specific auxotrophic strains-with diverse metabolic deficiencies-were co-cultured with an L-histidine auxotroph and optimized via adaptive laboratory evolution (ALE). Time-course sequencing revealed the genetic changes employed by each strain to achieve higher community growth rates and provided insight into mechanisms for adapting to the syntrophic niche. A community model of metabolism and gene expression was utilized to predict the relative community composition and fundamental characteristics of the evolved communities. This work presents new insight into the genetic strategies underlying viable nascent community formation and a cutting-edge computational method to elucidate metabolic changes that empower the creation of cooperative communities

Sistema para estimación de dosis interna de radiación absorbida en tratamientos de medicina nuclear

Si bien existen programas para calcular la cantidad de dosis interna absorbida en tratamientos de radioterapia, los profesionales de la salud reportan problemas en el uso de los mismos por la complejidad en la interacción, y los resultados de cálculos obtenidos no siempre satisfacen las expectativas de los profesionales. Esto genera rechazo en la utilización de tales programas de cálculo y los profesionales terminan usando hojas de cálculo para la determinación de la dosis a administrar, sin una elevada certeza en el control del cálculo de dosis, porque esos cálculos se realizan para un órgano aislado y por la imposibilidad de personalizar el cálculo para cada paciente. Este trabajo busca ofrecer un software que además de ser user-friendly para los profesionales de la salud permita incluir cualquier método de cálculo de dosis, minimizando el margen de error en dicho cálculo. Aprendiendo con redes neuronales a partir de los tratamientos exitosos.Sociedad Argentina de Informática e Investigación Operativ