Timber Quality Evolution- Its Complexities and Use

Much has been written recently about the projected demand-supply imbalance for wood in the years ahead. Louder voices and greater pressures are being heard and felt for action to intensify timber management and harvest from a shrinking land base to meet urgent needs of a rapidly growing population. Foresters confront a monumental task in attempting to meet that demand for consumable forest products, especially in light of the intensifying competition for less tangible forest values

Farmers' perceptions of the lay health worker on farms in the Western Cape, South Africa

This study is focussed on farms situated in the Boland health district of the Cape Winelands, South Africa. The aim was to explore, understand, and describe the perceptions of farmers of having a trained lay health worker (LHW) on the farm. A qualitative study design was applied. Data were collected during six in-depth interviews and two focus group discussions with participating farmers. The results show that farmers remained positive about the concept of having a trained LHW on the farm, but became frustrated with the lack of recognition of their and the LHWs' contribution by the public health service. Farmers who are willing to participate and remain active are key to introducing a farm community-based LHW intervention. Sustainable LHW interventions are dependent on public health sector support and recognition of all role players.Farm Management,

The identification and production of varieties that increase the value of oats as a profitable component of organic production

Two experiments, one comprising husked, and the other naked, oats were established at Wakelyns Agroforestry, Suffolk in October 2004 to determine traits and varieties of oats suited to organic systems, and whether growing variety mixtures conferred any advantage. Unselected F2 breeding lines were also included for selection. Husked varieties had relatively higher yields; this may have been partly the result of poor establishment in the naked varieties. Variety height was found to be an important characteristic; tall oat varieties out-yielded the dwarfs. Two of the three variety mixtures containing the naked oat variety Expression yielded 8 and 9 % higher than the average of the component varieties. The data will be verified in the second year of replicated trials (2005/06), which will include the best performing husked and naked varieties, and a mixture of superior IGER-bred F2 breeding lines

Sustainable production of organic wheat

The aim of the project is to use an ecological approach to analyse the interactions of a range of key agronomic variables in organic wheat production (wheat genotype, spatial arrangement of seed, seed density and wheat/white clover bi-cropping) to determine an optimal approach to improved and stabilised production. The fi rst set of data revealed that seedling competition was infl uenced by seed rate and drilling arrangement. Furthermore, the variety Hereward had increased emergence and establishment to Aristos. An interaction exists between wheat variety, seed rate and drilling arrangement on the level of canopy cover at different developmental stages – these factors are important for the suppression of weeds. The input of farmers in the selection of trial variables ensures results have a direct application to the industry. The results of yield and quality at harvest will provide further insights into the interaction of agronomic variables

A New Radio - X-Ray Probe of Galaxy Cluster Magnetic Fields

Results are presented of a new VLA-ROSAT study that probes the magnetic field strength and distribution over a sample of 16 ``normal'' low redshift (z < 0.1) galaxy clusters. The clusters span two orders of magnitude in X-ray luminosity, and were selected to be free of (unusual) strong radio cluster halos, and widespread cooling flows. Consistent with these criteria, most clusters show a relaxed X-ray morphology and little or no evidence for recent merger activity. Analysis of the rotation measure (RM) data shows cluster-generated Faraday RM excess out to ~0.5 Mpc from cluster centers. The results, combined with RM imaging of cluster-embedded sources and ROSAT X-ray profiles indicates that the hot intergalactic gas within these ``normal'' clusters is permeated with a high filling factor by magnetic fields at levels of = 5-10 (l/10 kpc)^{-1/2} microGauss, where l is the field correlation length. These results lead to a global estimate of the total magnetic energy in clusters, and give new insight into the ultimate energy origin, which is likely gravitational. These results also shed some light on the cluster evolutionary conditions that existed at the onset of cooling flows.Comment: 6 pages, 1 figure, uses emulateapj5.sty, accepted by ApJ

Evolutionary breeding of healthy wheat: from plot to farm

Genetically diverse Composite Cross Populations (CCPs) may be useful in environmentally variable low-input systems as an alternative to pure line varieties. They are formed by hybridising lines with diverse evolutionary origins, bulking the F1 progeny, and allowing natural selection of the progeny in successive crop environments. CCPs derived from 10 high yielding parents (YCCPs), 12 high quality parents (QCCPs), or all 22 parents (YQCCPs), were grown at four sites (2 organic, 2 conventional) in the UK; they are currently (2006) in F5. The YCCPs out yielded the QCCPs, which had better quality characteristics. Although the CCPs performed within the range of the parents, the values obtained were often better than the mean of the parents. Some population samples are now being grown on farms and other sites in England, France, Germany and Hungary

Complement deficiencies limit CD20 monoclonal antibody treatment efficacy in CLL

Monoclonal antibodies (MAbs) form a central part of chronic lymphocytic leukaemia (CLL) treatment. We therefore evaluated whether complement defects in CLL patients reduced the induction of complement-dependent cytotoxicity (CDC) by using anti-CD20 MAbs rituximab (RTX) and ofatumumab (OFA). Ofatumumab elicited higher CDC levels than RTX in all CLL samples examined, particularly in poor prognosis cohorts (11q− and 17p−). Serum sample analyses revealed that 38.1% of patients were deficient in one or more complement components, correlating with reduced CDC responses. Although a proportion of patients with deficient complement levels initially induced high levels of CDC, on secondary challenge CDC activity in sera was significantly reduced, compared with that in normal human serum (NHS; P&#60;0.01; n=52). In addition, a high CLL cell number contributed to rapid complement exhaustion. Supplementing CLL serum with NHS or individual complement components, particularly C2, restored CDC on secondary challenge to NHS levels (P&#60;0.0001; n=9). In vivo studies revealed that complement components were exhausted in CLL patient sera post RTX treatment, correlating with an inability to elicit CDC. Supplementing MAb treatment with fresh-frozen plasma may therefore maintain CDC levels in CLL patients with a complement deficiency or high white blood cell count. This study has important implications for CLL patients receiving anti-CD20 MAb therapy

Heralded state preparation in a superconducting qubit

We demonstrate high-fidelity, quantum nondemolition, single-shot readout of a superconducting flux qubit in which the pointer state distributions can be resolved to below one part in 1000. In the weak excitation regime, continuous measurement permits the use of heralding to ensure initialization to a fiducial state, such as the ground state. This procedure boosts readout fidelity to 93.9% by suppressing errors due to spurious thermal population. Furthermore, heralding potentially enables a simple, fast qubit reset protocol without changing the system parameters to induce Purcell relaxation.Comment: 5 pages, 5 figure

Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics.

BackgroundAnimal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries. Next-generation transcriptomics and proteomics provide unparalleled, but underexploited, capabilities for venom characterization. We combined multi-tissue RNA-Seq with mass spectrometry and bioinformatic analyses to determine venom gland specific transcripts and venom proteins from the Western black widow spider (Latrodectus hesperus) and investigated their evolution.ResultsWe estimated expression of 97,217 L. hesperus transcripts in venom glands relative to silk and cephalothorax tissues. We identified 695 venom gland specific transcripts (VSTs), many of which BLAST and GO term analyses indicate may function as toxins or their delivery agents. ~38% of VSTs had BLAST hits, including latrotoxins, inhibitor cystine knot toxins, CRISPs, hyaluronidases, chitinase, and proteases, and 59% of VSTs had predicted protein domains. Latrotoxins are venom toxins that cause massive neurotransmitter release from vertebrate or invertebrate neurons. We discovered ≥ 20 divergent latrotoxin paralogs expressed in L. hesperus venom glands, significantly increasing this biomedically important family. Mass spectrometry of L. hesperus venom identified 49 proteins from VSTs, 24 of which BLAST to toxins. Phylogenetic analyses showed venom gland specific gene family expansions and shifts in tissue expression.ConclusionsQuantitative expression analyses comparing multiple tissues are necessary to identify venom gland specific transcripts. We present a black widow venom specific exome that uncovers a trove of diverse toxins and associated proteins, suggesting a dynamic evolutionary history. This justifies a reevaluation of the functional activities of black widow venom in light of its emerging complexity

The role of proton precipitation in Jovian aurora: Theory and observation

It was proposed that the Jovian auroral emissions observed by Voyager spacecraft could be explained by energetic protons precipitating into the upper atmosphere of Jupiter. Such precipitation of energetic protons results in Doppler-shifted Lyman alpha emission that can be quantitatively analyzed to determine the energy flux and energy distribution of the incoming particle beam. Modeling of the expected emission from a reasonably chosen Voyager energetic proton spectrum can be used in conjunction with International Ultraviolet Explorer (IUE) observations, which show a relative lack of red-shifted Lyman alpha emission, to set upper limits on the amount of proton precipitation taking place in the Jovian aurora. Such calculations indicate that less than 10 percent of the ultraviolet auroral emissions at Jupiter can be explained by proton precipitation