51 research outputs found
Reliability of the CARE rule and the HEART score to rule out an acute coronary syndrome in non-traumatic chest pain patients
In patients consulting in the Emergency Department for chest pain, a HEART score †3 has been shown to rule out an acute coronary syndrome (ACS) with a low risk of major adverse cardiac event (MACE) occurrence. A negative CARE rule (†1) that stands for the first four elements of the HEART score may have similar rule-out reliability without troponin assay requirement. We aim to prospectively assess the performance of the CARE rule and of the HEART score to predict MACE in a chest pain population. Prospective two-center non-interventional study. Patients admitted to the ED for non-traumatic chest pain were included, and followed-up at 6 weeks. The main study endpoint was the 6-week rate of MACE (myocardial infarction, coronary angioplasty, coronary bypass, and sudden unexplained death). 641 patients were included, of whom 9.5% presented a MACE at 6 weeks. The CARE rule was negative for 31.2% of patients, and none presented a MACE during follow-up [0, 95% confidence interval: (0.0â1.9)]. The HEART score was †3 for 63.0% of patients, and none presented a MACE during follow-up [0% (0.0â0.9)]. With an incidence below 2% in the negative group, the CARE rule seemed able to safely rule out a MACE without any biological test for one-third of patients with chest pain and the HEART score for another third with a single troponin assay
Publisherâs Note: âNonlinear kinetic modeling of stimulated Raman scattering in a multidimensional geometryâ [Phys. Plasmas 19, 056301 (2012)]
Saturation mechanisms of backward stimulated Raman scattering in a one-dimensional geometry
Antihyaluronidase Content of Serum in Children Suffering from Hemolytic Streptococcal Infections, Rheumatic Fever and Other Diseases
The simulations of charged particle acceleration from gas target at 20 TW SOKOL-P laser with intensity of 5â 1019 W/cm2
2D PIC code simulations have been performed for the optimization of gas jet target parameters to achieve a maximal energy and efficiency of charged particle acceleration in planned experiments at the 20 TW picosecond SOKOL-P laser. These calculations specify an opportunity to obtain energy up to Ee ⌠200 MeV and efficiency ηe ⌠10% for accelerated electrons and Ep ⌠30 â 50 MeV and ηp ⌠5% for accelerated protons in these experiments at laser intensity I ⌠5 â
1019 W/cm2. They show the necessity of providing a formation of hydrogen jets with diameter ⌠1mm, a gas molecule concentration ⌠2 â
1019 cmâ3 and steep density gradients ⌠200 ÎŒm at the edge of the gas jet target for achieving these parameters of laser accelerated particle beams
Nonlinear kinetic modeling and simulations of Raman scattering in a two-dimensional geometry
In this paper, we present our nonlinear kinetic modeling of stimulated Raman scattering (SRS) by the means of envelope equations, whose coefficients have been derived using a mixture of perturbative and adiabatic calculations. First examples of the numerical resolution of these envelope equations in a two-dimensional homogeneous plasma are given, and the results are compared against those of particle-in-cell (PIC) simulations. These preliminary comparisons are encouraging since our envelope code provides threshold intensities consistent with those of PIC simulations while requiring computational resources reduced by 4 to 5 orders of magnitude compared to full-kinetic codes
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