364 research outputs found
Image transfer through a chaotic channel by intensity correlations
The three-wave mixing processes in a second-order nonlinear medium can be
used for imaging protocols, in which an object field is injected into the
nonlinear medium together with a reference field and an image field is
generated. When the reference field is chaotic, the image field is also chaotic
and does not carry any information about the object. We show that a clear image
of the object be extracted from the chaotic image field by measuring the
spatial intensity correlations between this field and one Fourier component of
the reference. We experimentally verify this imaging protocol in the case of
frequency downconversion.Comment: 17 pages, 7 figure
Certification of the Mass fractions of Crude Protein, Crude Oils and Fats, Crude Fibre, Crude Ash and Phosphorus (According to Methods Specifications Laid down in EU-Legislation) and of Copper, Calcium and Magnesium, BCR-708 (Synthetic Dairy Feed), ....
Abstract not availableJRC.D-Institute for Reference Materials and Measurements (Geel
Nature of light correlations in ghost imaging
We investigate the nature of correlations in Gaussian light sources used for
ghost imaging. We adopt methods from quantum information theory to distinguish
genuinely quantum from classical correlations. Combining a microscopic analysis
of speckle-speckle correlations with an effective coarse-grained description of
the beams, we show that quantum correlations exist even in `classical'-like
thermal light sources, and appear relevant for the implementation of ghost
imaging in the regime of low illumination. We further demonstrate that the
total correlations in the thermal source beams effectively determine the
quality of the imaging, as quantified by the signal-to-noise ratio.Comment: 12 pages, 5 figures. To appear in Scientific Reports (NPG
Схеми скорочення необхідного об'єму вимірювань у методі контролю стаціонарної підйомної установки
Предлагается последовательная процедура принятия решения относительно вектора характеристик контролируемой стационарной подъемной установки, которая является некоторым обобщением процедуры Вальда и позволяет получить выигрыш в среднем объеме испытаний, аналогичный обычному «вальдовскому» выигрышу для случая двух гипотез. Предлагаемая последовательная процедура позволяет учитывать дополнительную информацию и за счет этого получить добавочный выигрыш в объеме контроля стационарной подъемной установки.Offers a consistent decision-making procedure for the vector characteristics of the controlled stationary hoist, which is a generalization of Wald's procedure and provides a gain in the average volume of tests, similar to the usual "of Wald's" winning the case of two hypotheses. The proposed sequential procedure takes into account the additional information
and thereby obtain additional gains in the amount of control a stationary hoist
Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance
Drugs inhibiting the influenza A virus (IAV) neuraminidase (NA) are the cornerstone of anti-IAV chemotherapy and prophylaxis in man. Drug-resistant mutations in NA arise frequently in human isolates, limiting the therapeutic application of NA inhibitors. Here, we show that antibody-driven antigenic variation in one domain of the H1 hemagglutinin Sa site leads to compensatory mutations in NA, resulting in NA antigenic variation and acquisition of drug resistance. These findings indicate that influenza A virus resistance to NA inhibitors can potentially arise from antibody driven HA escape, confounding analysis of influenza NA evolution in nature
Bringing AI to the clinic: blueprint for a vendor-neutral AI deployment infrastructure
AI provides tremendous opportunities for improving patient care, but at present there is little evidence of real-world uptake. An important barrier is the lack of well-designed, vendor-neutral and future-proof infrastructures for deployment. Because current AI algorithms are very narrow in scope, it is expected that a typical hospital will deploy many algorithms concurrently. Managing stand-alone point solutions for all of these algorithms will be unmanageable. A solution to this problem is a dedicated platform for deployment of AI. Here we describe a blueprint for such a platform and the high-level design and implementation considerations of such a system that can be used clinically as well as for research and development. Close collaboration between radiologists, data scientists, software developers and experts in hospital IT as well as involvement of patients is crucial in order to successfully bring AI to the clinic
Extracting Spatial Information from Noise Measurements of Multi-Spatial-Mode Quantum States
We show that it is possible to use the spatial quantum correlations present
in twin beams to extract information about the shape of a mask in the path of
one of the beams. The scheme, based on noise measurements through homodyne
detection, is useful in the regime where the number of photons is low enough
that direct detection with a photodiode is difficult but high enough that
photon counting is not an option. We find that under some conditions the use of
quantum states of light leads to an enhancement of the sensitivity in the
estimation of the shape of the mask over what can be achieved with a classical
state with equivalent properties (mean photon flux and noise properties). In
addition, we show that the level of enhancement that is obtained is a result of
the quantum correlations and cannot be explained with only classical
correlations
Heralding efficiency and correlated-mode coupling of near-IR fiber-coupled photon pairs
We report on a systematic experimental study of the heralding efficiency and generation rate of telecom-band infrared photon pairs generated by spontaneous parametric down-conversion and coupled to single-mode optical fibers. We define the correlated-mode coupling efficiency, an inherent source efficiency, and explain its relation to heralding efficiency. For our experiment, we developed a reconfigurable computer-controlled pump-beam and collection-mode optical apparatus which we used to measure the generation rate and correlated-mode coupling efficiency. The use of low-noise, high-efficiency superconducting nanowire single-photon detectors in this setup allowed us to explore focus configurations with low overall photon flux. The measured data agree well with theory, and we demonstrated a correlated-mode coupling efficiency of 97% ± 2%, which is the highest efficiency yet achieved for this type of system. These results confirm theoretical treatments and demonstrate that very high overall heralding efficiencies can, in principle, be achieved in quantum optical systems. It is expected that these results and techniques will be widely incorporated into future systems that require, or benefit from, a high heralding efficiency.United States. Dept. of Defense. Assistant Secretary of Defense for Research & Engineering (Air Force Contract FA8721-05-C-0002
Conclusive quantum steering with superconducting transition edge sensors
Quantum steering allows two parties to verify shared entanglement even if one
measurement device is untrusted. A conclusive demonstration of steering through
the violation of a steering inequality is of considerable fundamental interest
and opens up applications in quantum communication. To date all experimental
tests with single photon states have relied on post-selection, allowing
untrusted devices to cheat by hiding unfavourable events in losses. Here we
close this "detection loophole" by combining a highly efficient source of
entangled photon pairs with superconducting transition edge sensors. We achieve
an unprecedented ~62% conditional detection efficiency of entangled photons and
violate a steering inequality with the minimal number of measurement settings
by 48 standard deviations. Our results provide a clear path to practical
applications of steering and to a photonic loophole-free Bell test.Comment: Preprint of 7 pages, 3 figures; the definitive version is published
in Nature Communications, see below. Also, see related experimental work by
A. J. Bennet et al., arXiv:1111.0739 and B. Wittmann et al., arXiv:1111.076
Hemagglutinin Receptor Binding Avidity Drives Influenza A Virus Antigenic Drift
Refer to Web version on PubMed Central for supplementary material.Rapid antigenic evolution in the influenza A virus hemagglutinin precludes effective vaccination with existing vaccines. To understand this phenomenon, we passaged virus in mice immunized with influenza vaccine. Neutralizing antibodies selected mutants with single–amino acid hemagglutinin substitutions that increased virus binding to cell surface glycan receptors. Passaging these high-avidity binding mutants in naïve mice, but not immune mice, selected for additional hemagglutinin substitutions that decreased cellular receptor binding avidity. Analyzing a panel of monoclonal antibody hemagglutinin escape mutants revealed a positive correlation between receptor binding avidity and escape from polyclonal antibodies. We propose that in response to variation in neutralizing antibody pressure between individuals, influenza A virus evolves by adjusting receptor binding avidity via amino acid substitutions throughout the hemagglutinin globular domain, many of which simultaneously alter antigenicity.National Institute of Mental Health (U.S.). Division of Intramural ResearchNational Institute of Allergy and Infectious Diseases (U.S.)Singapore-MIT Alliance for Research and TechnologyNational Institute of General Medical Sciences (U.S.) (GM 57073)National Institute of General Medical Sciences (U.S.) (U54GM62116
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