Pseudoscalar Meson Mixing in Effective Field Theory

We show that for any effective field theory of colorless meson fields, the mixing schemes of particle states and decay constants are not only related but also determined exclusively by the kinetic and mass Lagrangian densities. In the general case, these are bilinear in terms of the intrinsic fields and involve non-diagonal kinetic and mass matrices. By applying three consecutive steps this Lagrangian can be reduced into the standard quadratic form in terms of the physical fields. These steps are : (i) the diagonalization of the kinetic matrix, (ii) rescaling of the fields, and (iii) the diagonalization of the mass matrix. In case, where the dimensions of the non-diagonal kinetic and mass sub-matrices are respectively, $k\times k$ and $n\times n$, this procedure leads to mixing schemes which involve $[k(k-1)/2] + [n(n-1)/2]$ angles and $k$ field rescaling parameters. This observation holds true irrespective with the type of particle interactions presumed. The commonly used mixing schemes, correspond to a proper choice of the kinetic and mass matrices, and are derived as special cases. In particular, $\eta$-$\eta '$ mixing, requires one angle, if and only if, the kinetic term with the intrinsic fields has a quadratic form.Comment: REVTeX, 6 page

η\eta and η′\eta' mesons in the Dyson-Schwinger approach at finite temperature

We study the temperature dependence of the pseudoscalar meson properties in a relativistic bound-state approach exhibiting the chiral behavior mandated by QCD. Concretely, we adopt the Dyson-Schwinger approach with a rank-2 separable model interaction. After extending the model to the strange sector and fixing its parameters at zero temperature, T=0, we study the T-dependence of the masses and decay constants of all ground-state mesons in the pseudoscalar nonet. Of chief interest are $\eta$ and $\eta^\prime$. The influence of the QCD axial anomaly on them is successfully obtained through the Witten-Veneziano relation at T=0. The same approach is then extended to T>0, using lattice QCD results for the topological susceptibility. The most conspicuous finding is an increase of the $\eta^\prime$ mass around the chiral restoration temperature $T_{\rm Ch}$, which would suggest a suppression of $\eta^\prime$ production in relativistic heavy-ion collisions. The increase of the $\eta^\prime$ mass may also indicate that the extension of the Witten-Veneziano relation to finite temperatures becomes unreliable around and above $T_{\rm Ch}$. Possibilities of an improved treatment are discussed.Comment: 13 pages, 15 figure

Antibody quality and protection from lethal ebola virus challenge in nonhuman primates immunized with rabies virus based bivalent vaccine.

We have previously described the generation of a novel Ebola virus (EBOV) vaccine platform based on (a) replication-competent rabies virus (RABV), (b) replication-deficient RABV, or (c) chemically inactivated RABV expressing EBOV glycoprotein (GP). Mouse studies demonstrated safety, immunogenicity, and protective efficacy of these live or inactivated RABV/EBOV vaccines. Here, we evaluated these vaccines in nonhuman primates. Our results indicate that all three vaccines do induce potent immune responses against both RABV and EBOV, while the protection of immunized animals against EBOV was largely dependent on the quality of humoral immune response against EBOV GP. We also determined if the induced antibodies against EBOV GP differ in their target, affinity, or the isotype. Our results show that IgG1-biased humoral responses as well as high levels of GP-specific antibodies were beneficial for the control of EBOV infection after immunization. These results further support the concept that a successful EBOV vaccine needs to induce strong antibodies against EBOV. We also showed that a dual vaccine against RABV and filoviruses is achievable; therefore addressing concerns for the marketability of this urgently needed vaccine

Quick and robust method for trace determination of MeHg in rice and rice products without derivatisation

Peer reviewedPostprin

Goldstone Bosons in Effective Theories with Spontaneously Broken Flavour Symmetry

The Flavour Symmetry of the Standard Model (SM) gauge sector is broken by the fermion Yukawa couplings. Promoting the Yukawa matrices to scalar spurion fields, one can break the flavour symmetry spontaneously by giving appropriate vacuum expectation values (VEVs) to the spurion fields, and one encounters Goldstone modes for every broken flavour symmetry generator. In this paper, we point out various aspects related to the possible dynamical interpretation of the Goldstone bosons: (i) In an effective-theory framework with local flavour symmetry, the Goldstone fields represent the longitudinal modes for massive gauge bosons. The spectrum of the latter follows the sequence of flavour-symmetry breaking related to the hierarchies in Yukawa couplings and flavour mixing angles. (ii) Gauge anomalies can be consistently treated by adding higher-dimensional operators. (iii) Leaving the U(1) factors of the flavour symmetry group as global symmetries, the respective Goldstone modes behave as axions which can be used to resolve the strong CP problem by a modified Peccei-Quinn mechanism. (iv) The dynamical picture of flavour symmetry breaking implies new sources of flavour-changing neutral currents, which arise from integrating out heavy scalar spurion fields and heavy gauge bosons. The coefficients of the effective operators follow the minimal-flavour violation principle.Comment: 27 pages, abstract and introduction extended, more detailed discussion of heavy gauge boson spectrum and auxiliary heavy fermions, outline restructured. Matches version to be published in JHE

Study of exclusive processes e^+ e^- \to VP

This paper is devoted to consideration of the hard exclusive processes $e^+e^- \to VP$, where $V=\rho,\phi; P=\eta,\eta'$. Experimental measurement of the cross section of the process $e^+ e^- \to \phi\eta$ at BaBar collaboration at large center mass energy $\sqrt s=10.6$ GeV and some low energy experimental data $\sqrt s \sim 2-4$ GeV give us the possibility to study the cross section in the broad energy region. As the result, we have determined the asymptotic behavior of the cross section of $e^+ e^- \to \phi\eta$ in the limit $s \to \infty$, which is in agreement with perturbative QCD prediction. Assuming that the same asymptotic behavior is valid for the other processes under consideration and using low energy experimental data we have predicted the cross sections of these processes at energies $\sqrt s=3.67,~10.6$ GeV. In addition, we have calculated the cross sections of these processes at the same energies within perturbative QCD. Our results are in agreement with available experimental data.Comment: 10 pages, 2 tables, 6 figures; minor changes; article accepted to publication is Phys. Rev.

Postexposure Treatment of Marburg Virus Infection

Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection

Charmless two-body B decays: A global analysis with QCD factorization

In this paper, we perform a global analysis of $B \to PP$ and $PV$ decays with the QCD factorization approach. It is encouraging to observe that the predictions of QCD factorization are in good agreement with experiment. The best fit $\gamma$ is around $79^\circ$. The penguin-to-tree ratio $|P_{\pi \pi}/T_{\pi \pi}|$ of $\pi^+ \pi^-$ decays is preferred to be larger than 0.3. We also show the confidence levels for some interesting channels: $B^0 \to \pi^0 \pi^0$, $K^+ K^-$ and $B^+ \to \omega \pi^+$, $\omega K^+$. For $B \to \pi K^\ast$ decays, they are expected to have smaller branching ratios with more precise measurements.Comment: 20 pages, 4 figures, version to appear in Phys. Rev.

Bloch oscillations of magnetic solitons in anisotropic spin-1/2 chains

We study the quantum dynamics of soliton-like domain walls in anisotropic spin-1/2 chains in the presence of magnetic fields. In the absence of fields, domain walls form a Bloch band of delocalized quantum states while a static field applied along the easy axis localizes them into Wannier wave packets and causes them to execute Bloch oscillations, i.e. the domain walls oscillate along the chain with a finite Bloch frequency and amplitude. In the presence of the field, the Bloch band, with a continuum of extended states, breaks up into the Wannier-Zeeman ladder -- a discrete set of equally spaced energy levels. We calculate the dynamical structure factor in the one-soliton sector at finite frequency, wave vector, and temperature, and find sharp peaks at frequencies which are integer multiples of the Bloch frequency. We further calculate the uniform magnetic susceptibility and find that it too exhibits peaks at the Bloch frequency. We identify several candidate materials where these Bloch oscillations should be observable, for example, via neutron scattering measurements. For the particular compound CoCl_2.2H_2O we estimate the Bloch amplitude to be on the order of a few lattice constants, and the Bloch frequency on the order of 100 GHz for magnetic fields in the Tesla range and at temperatures of about 18 Kelvin.Comment: 31 single-spaced REVTeX pages, including 7 figures embedded with eps

Implications of Recent Bˉ0→D(∗)0X0\bar{B}^0\to D^{(*)0}X^0 Measurements

The recent measurements of the color-suppressed modes $\bar B^0\to D^{(*)0}\pi^0$ imply non-vanishing relative final-state interaction (FSI) phases among various $\bar B\to D\pi$ decay amplitudes. Depending on whether or not FSIs are implemented in the topological quark-diagram amplitudes, two solutions for the parameters $a_1$ and $a_2$ are extracted from data using various form-factor models. It is found that $a_2$ is not universal: $|a_2(D\pi)|= 0.40-0.55$ and $|a_2(D^*\pi)|= 0.25-0.35$ with a relative phase of order $(50-55)^\circ$ between $a_1$ and $a_2$. If FSIs are not included in quark-diagram amplitudes from the outset, $a_2^{eff}/a_1^{eff}$ and $a_2^{eff}$ will become smaller. The large value of $|a_2(D\pi)|$ compared to $|a_2^{eff}(D\pi)|$ or naive expectation implies the importance of long-distance FSI contributions to color-suppressed internal $W$-emission via final-state rescatterings of the color-allowed tree amplitude.Comment: 17 pages. The Introduction is substantially revised and the order of the presentation in Sec. 2 is rearranged. To appear in Phys. Re