Intermediate-mass Black Holes in Galactic Nuclei

We present the first homogeneous sample of intermediate-mass black hole candidates in active galactic nuclei. Starting with broad-line active nuclei from the Sloan Digital Sky Survey, we use the linewidth-luminosity-mass scaling relation to select a sample of 19 galaxies in the mass range M_BH ~ 8 x 10^4 - 10^6 solar masses. In contrast to the local active galaxy population, the host galaxies are ~1 mag fainter than M* and thus are probably late-type systems. The active nuclei are also faint, with M_g ~ -15 to -18 mag, while the bolometric luminosities are close to the Eddington limit. The spectral properties of the sample are compared to the related class of objects known as narrow-line Seyfert 1 galaxies. We discuss the importance of our sample as observational analogues of primordial black holes, contributors to the integrated signal for future gravitational wave experiments, and as a valuable tool in the calibration of the M-sigma relation.Comment: 4 pages, 4 figures. To appear in "The Interplay among Black Holes, Stars and ISM in Galactic Nuclei," Proc. IAU 222 (Gramado, Brazil), eds Th. Storchi Bergmann, L.C. Ho, H.R. Schmit

Binding Energies and Scattering Observables in the ^3He^4He_2 Atomic System

The ^3He^4He_2 three-atomic system is studied on the basis of a hard-core version of the Faddeev differential equations. The binding energy of the ^3He^4He_2 trimer, scattering phase shifts, and the scattering length of a ^3He atom off a ^4He dimer are calculated using the LM2M2 and TTY He-He interatomic potentials.Comment: Contribution to Proceedings of the 17th International IUPAP Conference on Few-Body Problems in Physics (Durham, North Carolina, USA, June 5-10, 2003

Deconfinement and cold atoms in optical lattices

Despite the fact that by now one dimensional and three dimensional systems of interacting particles are reasonably well understood, very little is known on how to go from the one dimensional physics to the three dimensional one. This is in particular true in a quasi-one dimensional geometry where the hopping of particles between one dimensional chains or tubes can lead to a dimensional crossover between a Luttinger liquid and more conventional high dimensional states. Such a situation is relevant to many physical systems. Recently cold atoms in optical traps have provided a unique and controllable system in which to investigate this physics. We thus analyze a system made of coupled one dimensional tubes of interacting fermions. We explore the observable consequences, such as the phase diagram for isolated tubes, and the possibility to realize unusual superfluid phases in coupled tubes systems.Comment: Proceedings of the conference on "Quantum Many Body Theories 13", to be published by World Scientifi

"Low-state" Black Hole Accretion in Nearby Galaxies

I summarize the main observational properties of low-luminosity AGNs in nearby galaxies to argue that they are the high-mass analogs of black hole X-ray binaries in the "low/hard" state. The principal characteristics of low-state AGNs can be accommodated with a scenario in which the central engine is comprised of three components: an optically thick, geometrically accretion disk with a truncated inner radius, a radiatively inefficient flow, and a compact jet.Comment: 8 pages. To appear in From X-ray Binaries to Quasars: Black Hole Accretion on All Mass Scales, ed. T. J. Maccarone, R. P. Fender, and L. C. Ho (Dordrecht: Kluwer

Two--Electron Atoms in Short Intense Laser Pulses

We discuss a method of solving the time dependent Schrodinger equation for atoms with two active electrons in a strong laser field, which we used in a previous paper [A. Scrinzi and B. Piraux, Phys. Rev. A 56, R13 (1997)] to calculate ionization, double excitation and harmonic generation in Helium by short laser pulses. The method employs complex scaling and an expansion in an explicitly correlated basis. Convergence of the calculations is documented and error estimates are provided. The results for Helium at peak intensities up to 10^15 W/cm^2 and wave length 248 nm are accurate to at least 10 %. Similarly accurate calculations are presented for electron detachment and double excitation of the negative hydrogen ion.Comment: 14 pages, including figure

Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis

Objectives: To identify risk factors for failure of outpatient antibiotic therapy (OPAT) in infective endocarditis (IE). Patients and methods: We identified IE cases managed at a single centre over 12 years from a prospectively maintained database. ‘OPAT failure’ was defined as unplanned readmission or antibiotic switch due to adverse drug reaction or antibiotic resistance. We analysed patient and disease-related risk factors for OPAT failure by univariate and multivariate logistic regression. We also retrospectively collected follow-up data on adverse disease outcome (defined as IE-related death or relapse) and performed Kaplan–Meier survival analysis up to 36 months following OPAT. Results: We identified 80 episodes of OPAT in IE. Failure occurred in 25/80 episodes (31.3%). On multivariate analysis, cardiac or renal failure [pooled OR 7.39 (95% CI 1.84–29.66), P = 0.005] and teicoplanin therapy [OR 8.69 (95% CI 2.01–37.47), P = 0.004] were independently associated with increased OPAT failure. OPAT failure with teicoplanin occurred despite therapeutic plasma levels. OPAT failure predicted adverse disease outcome up to 36 months (P = 0.016 log-rank test). Conclusions: These data caution against selecting patients with endocarditis for OPAT in the presence of cardiac or renal failure and suggest teicoplanin therapy may be associated with suboptimal OPAT outcomes. Alternative regimens to teicoplanin in the OPAT setting should be further investigated

Limits on MeV Dark Matter from the Effective Number of Neutrinos

Thermal dark matter that couples more strongly to electrons and photons than to neutrinos will heat the electron-photon plasma relative to the neutrino background if it becomes nonrelativistic after the neutrinos decouple from the thermal background. This results in a reduction in N_eff below the standard-model value, a result strongly disfavored by current CMB observations. Taking conservative lower bounds on N_eff and on the decoupling temperature of the neutrinos, we derive a bound on the dark matter particle mass of m_\chi > 3-9 MeV, depending on the spin and statistics of the particle. For p-wave annihilation, our limit on the dark matter particle mass is stronger than the limit derived from distortions to the CMB fluctuation spectrum produced by annihilations near the epoch of recombination.Comment: 5 pages, 1 figure, discussion added, references added and updated, labels added to figure, to appear in Phys. Rev.