New atlas of open star clusters

Due to numerous new discoveries of open star clusters in the last two decades, astronomers need an easy-to-use resource to get visual information on the relative position of clusters in the sky. Therefore we propose a new atlas of open star clusters. It is based on a table compiled from the largest modern cluster catalogues. The atlas shows the positions and sizes of 3291 clusters and associations, and consists of two parts. The first contains 108 maps of 12 by 12 degrees with an overlapping of 2 degrees in three strips along the Galactic equator. The second one is an online web application, which shows a square field of an arbitrary size, either in equatorial coordinates or in galactic coordinates by request. The atlas is proposed for the sampling of clusters and cluster stars for further investigation. Another use is the identification of clusters among overdensities in stellar density maps or among stellar groups in images of the sky. © 2017 A. F. Seleznev et al.Acknowledgment: The work of Anton F. Seleznev was partly supported by the Ministry of Education and Science (the basic part of the State assignment, RK no. AAAA-A17-117030310283-7). The work of Anton F. Seleznev and of Eka-terina Avvakumova was supported also by the Act no. 211 of the Government of the Russian Federation, agreement no. 02.A03.21.0006. Authors are very grateful to Tatiana Selezneva for the graphic design of the web application

THE ROLE OF POSTPARTUM VAGINAL BRUISING IN THE DEVELOPMENT OF ACUTE MASSIVE BLOOD LOSS

Purpose: To estimate the efficiency of the ultrasound diagnosis of postpartum vaginal hematoma in women with varicose veins of the lower extremitiesMaterials and Methods: 120 women with varicose veins of the lower extremities were examined. In 2 hours after birth for women was conducted transperineal ultrasound - research by vaginal and perineal ultrasound scanner PHILLIPS HD- 11.Results: Vaginal hematoma was detected in 31 (25.8%) women , and only 10 (8 %) had a damage of integrity of the mucous membrane. The study found that vaginal hematoma size 10,1±3,6 cm at the beginning of the formation can be asymptomatic , which may cause underestimation of the total blood loss in women with postpartum hemorrhage due to a variety of other competing causes.Summary: The use of analgesia in labor hinders timely diagnosis of postpartum hematomas of vulva and vagina

Application of optical non-invasive methods to diagnose the state of the lower limb tissues in patients with diabetes mellitus

The paper shows the possibility of assessing the functional state of microcirculatory-tissue systems of patients with diabetes mellitus by laser Doppler flowmetry (LDF), diffuse reflectance spectroscopy (DRS) and fluorescence spectroscopy (FS) methods. A review of the existing non-invasive optical technologies used to assess the state of microcirculation and oxygen metabolism in tissues of patients with diabetes is conducted. A series of experimental studies involving 76 patients with diabetes and 46 healthy volunteers was carried out. A wavelet analysis of LDF-grams was used to evaluate the adaptive changes of microcirculation during the temperature tests. The obtained data revealed that the proposed methodology in the form of combined use of several diagnostic technologies (LDF, FS and DRS) allows us to detect the presence or absence of trophic disorders and to evaluate adaptation processes during thermal tests

EFFECT OF LASER PROCESSING T15K6 BRAND HARD ALLOY ON MECHANICAL PROPERTIES

Рассмотрены физико-механические свойства твердого сплава до и после лазерного упрочнения, такие как твердость и износостойкость, с целью изучения влияния времени лазерного воздействия на эксплуатационные свойства твердого сплава марки Т15К6. Установлено, что существует взаимосвязь между временем лазерного упрочнения и его физико-механическими свойствами.The physical and mechanical properties of solid alloy before and after laser hardening such as hardness and wear resistance in order to study the effect of time of the laser effects on performance characteristics of solid T15K6 grade alloy. It is established that there is a relationship between time and a laser hardening its physico-mechanical properties

Online atlas of open star clusters

Использование онлайн-атласа рассеянных звездных скоплений демонстрируется на ряде примеров.An application of the online atlas of open star clusters is demonstrated on a number of examples.Часть работ проведена при финансовой поддержке государства в лице Министерства образования и науки Российской Федерации (базовая часть госзадания, РК № AAAA-A17-117030310283-7), а также при финансовой поддержке Правительства Российской Федерации (постановление № 211, контракт № 02.A03.21.0006)

Содержание иммуноглобулинов A, M, G в слезной жидкости у больных первичной открытоугольной глаукомой

PURPOSE: To define changes of immunoglobulins A, M, G in the tear fluid of patients with primary open-angle glaucoma (POAG). METHODS: We investigated the content of serum immunoglobulins and secretory immunoglobulin A in the tear fluid of patients with POAG and people with risk of its development. RESULTS: The level of IgG, which is the main immunoglobulin of the secondary immune response, was slightly elevated. Investigation of IgA concentration in the serum of patients with POAG showed an increase. Serum IgA concentration in the risk group almost did not differ from the control group. CONCLUSION: The study of immunoglobulin G, M and A in the serum of patients with POAG showed a slight increase Conflicts of Interest and Source of Funding: none declared. in their concentrations, indicating the activation of humoral mechanisms of immunopathogenesis in patients with POAG. Concentrations of secretory immunoglobulin A (sIgA) in the tear fluid was increased both in patients with POAG and in the risk group. It gives reason to consider the local humoral mechanisms an important link in the development of immune inflammation in primary open-angle glaucoma. Selective accumulation of sIgA in the tear fluid indicates an increase in the protective function of the mucous in response to any antigen, toxin, autoantigen, and the aim to limit the development of the pathological process.Цель. Установить изменения содержания иммуноглобулинов A, M, G в слезной жидкости у больных первичной открытоугольной глаукомой (ПОУГ). материалы и методы. ние и анализ уровня сывороточных иммуноглобулинов основных классов и секреторного иммуноглобулина А в слезной жидкости пациентов с ПОУГ и в группе риска ее развития. РЕЗУЛЬТАТЫ. Содержание IgG, являющегося основным иммуноглобулином вторичного иммунного ответа, было несколько повышено. Исследование концентрации ^А в сыворотке крови у больных ПОУГ показало ее некоторое увеличение, а у пациентов группы риска во всех подгруппах показатели почти не отличались от контроля. В слезной жидкости обнаружены значимые изменения секреторного иммуноглобулина А как у пациентов ПОУГ, так и в группе риска ее развития. ЗАКЛЮЧЕНИЕ. Результаты исследования иммуноглобулинов G, М, А в сыворотке крови у больных ПОУГ показали некоторое увеличение их концентраций, что свидетельствует об активации гуморальных механизмов иммунопатогенеза у больных ПОУГ. Локальные концентрации секреторного иммуноглобулина А (sIgA) превышали нормальные параметры как у больных ПОУГ, так и в группе риска. Это дает право считать локальные гуморальные механизмы одним из важных звеньев в развитии иммунного воспаления при ПОУГ. Селективное накопление sIgA в слезной жидкости свидетельствует об усилении защитной функции слизистых относительно любого антигена, токсина, аутоантигена, а также о стремлении ограничить развитие патологического процесса

The structure of the oropharyngeal genus Candida fungi community in HIVinfected patients

At the present time virtually no data are available about the structure of the genus Candida fungus able to target HIV-infected patients and serve as an etiological factor of candidiasis. The aforementioned shaped the aim of the study: to examine structure of the Candida genus community colonizing the oropharynx in HIV-infected patients with clinical manifestations of oropharyngeal candidiasis. There was conducted a microbiological study of the oropharynx in 31 HIV-infected patients (51.6% males and 48.4% females) with clinical manifestations of oropharyngeal candidiasis treated at Moscow Infectious Clinic No. 2 inpatient department in the years 2015–2017. We confirmed the diversity of the oropharyngeal Candida spp. community found in HIV-infected patients. Total 52 isolates of the genus Candida were isolated. C. albicans dominated in 57.7% cases, whereas C. glabrata prevailed (21.1%) among non-albicans species. Minor components were represented by C. tropicalis (11.5%) and C. krusei (9.6%). C. albicans and C. glabrata were sensitive to polyenes, whereas minor community components — to itroconazole and clotrimazole. The vast majority of fungal strains were resistant to fluconazole. The genus Candida community reveals a unique architecture so that any member may exist in the oropharyngeal biotope of HIV-infected patients as a monoculture or in association: homogeneous, consisting of a single species strains, or heterogeneous, formed by several species. Candida fungi in 18 patients (58.1%) were isolated as a monoculture, whereas in 13 (41.9%) subjects — in association consisting of 34 isolates (65.4% of total number), of which 16 (30.8%) and 18 (34.6%) were isolated from homogeneous and heterogeneous associations, respectively. There were identified 9 two-component associations (69.2%), and 4 (30.8%) consisting of three or more components. It turned out that pattern of the examined community was mainly determined by species composition that agrees with previous data. Most common associations were presented by C. krusei (100%) and C. albicans (73.3%). Upon that, most often C. albicans (72.7%) formed a homogeneous type of associations. Sensitivity of Candida fungi to antimycotic drugs also depended on the architecture of related community. C. albicans isolates in heterogeneous associations revealed a wide range of resistance acquired by contact with non-albicans species

Evidence for Low‐Pressure Crustal Anatexis During the Northeast Atlantic Break‐Up

While basaltic volcanism is dominant during rifting and continental breakup, felsic magmatism may be a significant component of some rift margins. During International Ocean Discovery Program (IODP) Expedition 396 on the continental margin of Norway, a graphite‐garnet‐cordierite bearing dacitic unit (the Mimir dacite) was recovered in two holes within early Eocene sediments on Mimir High (Site U1570), a marginal high on the Vøring Transform Margin. Here, we present a comprehensive textural, petrological, and geochemical study of the Mimir dacite in order to assess its origin and discuss the geodynamic implications. The major mineral phases (garnet, cordierite, quartz, plagioclase, alkali feldspar) are hosted in a fresh rhyolitic, vesicular, glassy matrix that is locally mingled with sediments. The major element chemistry of garnet and cordierite, the presence of zircon inclusions with inherited cores, and thermobarometric calculations all support an upper crustal metapelitic origin. While most magma‐rich margin models favor crustal anatexis in the lower crust, thermobarometric calculations performed here show that the Mimir dacite was produced at upper‐crustal depths (<5 kbar, 18 km depth) and high temperature (750–800°C) with up to 3 wt% water content. In situ U‐Pb analyses on zircon inclusions give a magmatic crystallization age of 54.6 ± 1.1 Ma, consistent with emplacement that post‐dates the Paleocene‐Eocene Thermal Maximum. Our results suggest that the opening of the Northeast Atlantic was associated with a phase of low‐pressure, high‐temperature crustal anatexis preceding the main phase of magmatism

Occurrence of sterile North-East Arctic cod individual

Based on histological analysis, cod individuals of older age groups that completely lost their reproductive capacity due to age-related gonads' degeneration have been considered. Such individuals have been found among both females and males. It has been revealed that in the gonads of sterile fish the replacement of gametes with connective tissue is taking place. According to the obtained data, the portion of sterile fish in samples among females of more than 100 cm has reached 2.2 %. The analysed sterile individuals are characterized by the drastically low gonadosomatic index while gepatosomatic index is mostly above the average. The reasons of age related sterility of the Barents Sea cod have not been discovered yet. The main role of age related fish reproductive condition is considered to be linked to hormonal regulation distortion of sexual cycle. Studying the distortion in the cod reproduction resulting in spawning skips or fish sterility is believed to be significant not only in theory, but in practice as well. Mature females' biomass is usually applied as reproductive potential indicator. However, the reproductive disorder leading to spawning skips affects reproductive abilities of the species that should be taken into account while estimating total allowable catches. In order to monitor abundance of sterile individuals of the Barents Sea cod, it has been proposed to add its maturity scale with VII stage for fish without reproductive capacity