Advanced beaded and tubular structural panels

A program to develop lightweight beaded and tubular structural panels is described. Applications include external surfaces, where aerodynamically acceptable, and primary structure protected by heat shields. The design configurations were optimized and selected with a computer code which iterates geometric parameters to satisfy strength, stability, and weight constraints. Methods of fabricating these configurations are discussed. Nondestructive testing produced extensive combined compression, shear, and bending test data on local buckling specimens and large panels. The optimized design concepts offer 25 to 30% weight savings compared to conventional stiffened sheet construction

Transition together: a study of pediatric patients with sickle cell disease as they transition to adult health care

Introduction: Improvement in medical care for sickle cell patients, translating into improvement in survival, has created the need for an active and intentional process of transition from pediatric to adult oriented health care. Objective: The purpose of this study was to determine the perspectives of adolescents and young adults with sickle cell disease as they prepare to transition, and to evaluate their current health care knowledge base and skills. Methods: A sample of 18 pediatric sickle cell patients age 15-22 years were recruited from a comprehensive Sickle Cell Center. Two sections of a four part questionnaire containing open- and closed-ended questions were assessed in order to explore these patients’ expectations and concerns about the transition process, and to evaluate their self-management of sickle cell disease. Results: Themes identified from the open-ended questions include: 1) Apprehension to Leaving Pediatric Care, 2) Forming New Relationships with Adult Providers, 3) Growing Up and Responsibility, 4) Worries Regarding Readiness and Support, and 5) Active Role in Transition. Statistical analysis of the close-ended questions revealed that patients appeared to have similar levels of independence in performing skills related to “Knowledge of Health Issues/Diagnosis, “Being Prepared”, and “Taking Charge”. However, there was a significantly lower level of independence in skills related to “Preparing for Legal/Other Issues After Age 18”. Overall, level of independence/readiness seemed to not be influenced by patients’ age, gender, or disease type. Discussion: Patients’ expectations and concerns about transition were mostly related to issues regarding patients’ perceived readiness for transition and the amount of support and understanding they receive from various health care providers. Additionally, continued monitoring and addressing of items in which the patient states he/she needs assistance with to achieve independence will be essential in the transition process. Conclusions and Public Health Significance: Transition from pediatric to adult care providers is a crucial step in the care of individuals with sickle cell disease. By eliciting the expectations and concerns of these patients’ and evaluating their knowledge base and skills, we are able to gather further insight into barriers to transition, and begin to develop a plan to address these obstacles

Knights, Dudes, and Shadow Steeds: Late Victorian Culture and the Early Cycling Clubs of New Orleans, 1881-1891

In the 1880s, two cycling clubs formed in New Orleans—the New Orleans Bicycle Club in 1881 and the Louisiana Cycling Club in 1887. These clubs were institutions of Victorian middle class culture that, like other athletic clubs, arose from the conditions of urban modernity and Victorian class anxieties. The NOBC, like other American cycling clubs, conformed to Victorian values of order and respectability. The attitudes and activities of the LCC, whose membership was younger, reflected instead a counter-Victorian ethos. This paper examines these two clubs in the context of late Victorian culture in New Orleans as it responded both to the conditions of urban modernity common to American cities in this period and to the particular cultural situation of New Orleans at the end of the nineteenth century, including proximity to and amalgamation with the recently-dominant, non-Anglo culture of the Creoles

Knights, Dudes, and Shadow Steeds: Late Victorian Culture and the Early Cycling Clubs of New Orleans, 1881-1891

In the 1880s, two cycling clubs formed in New Orleans—the New Orleans Bicycle Club in 1881 and the Louisiana Cycling Club in 1887. These clubs were institutions of Victorian middle class culture that, like other athletic clubs, arose from the conditions of urban modernity and Victorian class anxieties. The NOBC, like other American cycling clubs, conformed to Victorian values of order and respectability. The attitudes and activities of the LCC, whose membership was younger, reflected instead a counter-Victorian ethos. This paper examines these two clubs in the context of late Victorian culture in New Orleans as it responded both to the conditions of urban modernity common to American cities in this period and to the particular cultural situation of New Orleans at the end of the nineteenth century, including proximity to and amalgamation with the recently-dominant, non-Anglo culture of the Creoles

Water resources data for Alachua, Bradford, Clay, and Union Counties, Florida

A study of the water resources of Alachua, Bradford, Clay, and Union counties, Florida (fig. 1), was made by the Water Resources Division of the U. S. Geological Survey in cooperation with the Florida Geological Survey during the period 1957-61. The results of this study will be published by the Florida Geological Survey in the following reports by William E. Clark, Rufus H. Musgrove, Clarence G. Menke, and Joseph W. Cagle, Jr.: "Interim Report on the Water Resources of Alachua, Bradford, Clay, and Union Counties, Florida," "Water Resources of Alachua, Bradford, Clay, and Union Counties, Florida," and "Hydrology of Brooklyn Lake, near Keystone Heights, Florida." (Document has 161 pages.

Partially Demineralized Macroporous (PDM) Allografts for Cranial Tissue Engineering

poster abstractDecompressive Craniectomy is a cranial surgery where a large part of the cranial bone is removed in order to mitigate swelling in the brain tissue. Consequently, a scaffold biomaterial is required to substitute the lost bone. Ideal cranioplasty biomaterials should have the following features: fit the cranial defect and achieve complete closure, radiolucency, resistance to infections, no dilation with heat, resistance to biomechanical wear, pliability, and inexpensive. Partially Demineralized Macroporous (PDM) allografts exhibit such properties to correct these cranial defects. The main objectives of this study include: (1) examining the effects of demineralization and macroporosity formations on the mechanical and biological properties of allograft bone disks; (2) conducting finite element analysis (FEA) to stimulate the mechanical properties of the PDM allografts; and (3) evaluating the in vitro response of the PDM allografts utilizing pre-osteoblast cell lines. Tibias were harvested from Ossabaw mini-pigs and cylindrical cortical bone sections of 2 mm in thickness and 8 mm in diameter were obtained. Macropores of 600 micrometers in diameter were created to generate porosity levels of 0-40% in the bone disks. The bone disks were then demineralized in 14-wt% EDTA for 6 to 48 hours at 37℃. The relative stiffness was determined for each class using a material testing machine with a loading rate of 1 mm/min using a piston-on-ring set up. To analyze the deformation characteristics, FEA software LS-DYNA was employed. In order to understand the in vitro response, biocompatibility of PDM scaffolds were evaluated by culturing MC3T3-E1 cell lines where XTT and ALP assays were conducted. PDM allografts display the suitable stiffness required for cranial defects. The PDM allograft scaffolds aid in osteogenic proliferation and differentiation of pre-osteoblast cell lines in vitro. However, there will be further in vivo testing regarding the validity of PDM allografts in rat cranial defects. Mentor: Tien-Min Gabriel Chu, Department of Restorative DentistryDecompressive Craniectomy is a cranial surgery where a large part of the cranial bone is removed in order to mitigate swelling in the brain tissue. Consequently, a scaffold biomaterial is required to substitute the lost bone. Ideal cranioplasty biomaterials should have the following features: fit the cranial defect and achieve complete closure, radiolucency, resistance to infections, no dilation with heat, resistance to biomechanical wear, pliability, and inexpensive. Partially Demineralized Macroporous (PDM) allografts exhibit such properties to correct these cranial defects. The main objectives of this study include: (1) examining the effects of demineralization and macroporosity formations on the mechanical and biological properties of allograft bone disks; (2) conducting finite element analysis (FEA) to stimulate the mechanical properties of the PDM allografts; and (3) evaluating the in vitro response of the PDM allografts utilizing pre-osteoblast cell lines. Tibias were harvested from Ossabaw mini-pigs and cylindrical cortical bone sections of 2 mm in thickness and 8 mm in diameter were obtained. Macropores of 600 micrometers in diameter were created to generate porosity levels of 0-40% in the bone disks. The bone disks were then demineralized in 14-wt% EDTA for 6 to 48 hours at 37℃. The relative stiffness was determined for each class using a material testing machine with a loading rate of 1 mm/min using a piston-on-ring set up. To analyze the deformation characteristics, FEA software LS-DYNA was employed. In order to understand the in vitro response, biocompatibility of PDM scaffolds were evaluated by culturing MC3T3-E1 cell lines where XTT and ALP assays were conducted. PDM allografts display the suitable stiffness required for cranial defects. The PDM allograft scaffolds aid in osteogenic proliferation and differentiation of pre-osteoblast cell lines in vitro. However, there will be further in vivo testing regarding the validity of PDM allografts in rat cranial defects