"Single-cycle" ionization effects in laser-matter interaction

We investigate numerically effects related to ``single-cycle'' ionization of dense matter by an ultra-short laser pulse. The strongly non-adiabatic response of electrons leads to generation of a megagauss steady magnetic field in laser-solid interaction. By using two-beam interference, it is possible to create periodic density structures able to trap light and to generate relativistic ionization frontsComment: 12 pages, 6 figures, to be published in Laser and Particle Beam

CAESAR: SEWGS integration into an IGCC plant

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THERMODYNAMIC ORC CYCLE DESIGN OPTIMIZATION FOR MEDIUM-LOW TEMPERATURE ENERGY SOURCES

In the large spectrum of organic fluids suitable for Rankine cycles, a fluid that is already wellknown and available on industrial scale but currently excluded from this kind of application has been selected. This choice is due to the remarkable characteristics of the fluid, such as its high molecular weight, good thermal stability, non-flammability, and atoxicity. Compared to those fluids nowadays common in the ORC market, its thermodynamic properties and fluid dynamic behavior lead to a peculiar configuration of the cycle: • Supercritical cycle, when heat input is at medium-high temperature; • Massive regeneration, to obtain higher efficiency; • Low specific work of the turbine; • Relatively high volumetric expansion ratio and relatively low absolute inlet volumetric flow; Accordingly, an innovative cycle design has been developed, including a once-through Hairpin primary heat exchanger and a multi-stage radial outflow expander. This last innovative component has been designed to get the best performance with the chosen fluid: • The high inlet/outlet volumetric flow ratio is well combined with the change in cross section across the radius; • Compared to an axial turbine, the lower inlet volumetric flow is compensated by higher blades at the first stage. It is feasible thanks to the change in section available along the radius, so that there is no need for partial admission; • The prismatic blade leads to constant velocity diagrams across the blade span; • It minimizes tip leakages and disk friction losses, due to the single disk / multi-stage configuration; • The intrinsical limit of a radial outflow expander to develop high enthalpy drop is not relevant for this cycle, presenting itself a very low enthalpy drop. Moreover the tip speed is limited by the low speed of sound and consequently this kind of expander suits well with this cycle arrangement. The results of this study, conducted through thermodynamic simulations, CFD, stress analysis and economic optimization show an ORC system that reaches high efficiencies, comparable to those typical of existing system

CAPSULAR DEVICES FOR ORAL MODIFIED RELEASE OF DRUGS PREPARED BY INJECTION MOLDING

The research project was focused on the development of a pulsatile capsular-shaped drug delivery system (DDS) named Chronocap\u2122. It consists of a capsule shell, made of hydroxypropyl cellulose (HPC), prepared by injection molding (IM); it is intended to be filled with different types of drug preparations and to delay their liberation after oral administration. Such devices prepared by means of a prototype mold were demonstrated able to convey drug preparations giving rise to the expected pulsatile release performance, confirmed by in vivo data. The PhD project was undertaken aiming at improving the robustness and versatility of the Chronocap\u2122 device as well as enhancing the industrial scalability of its manufacturing process. For this purpose, two different tasks were pointed out: the improvement of the manufacturing process and of the technological characteristics of capsules on the one side, and the upgrade of applications of the device on the other. In this respect, the modulation of the lag phase of the capsular device and its possible exploitation in the design of a colon DDS were approached

Application of Hydrogen Selective Membranes to IGCC

AbstractThis study considers the integration of Pd-based H2-selective membranes in integrated gasifier combined cycles (IGCC) from both technical and economical point of view. The selected gasification system is based on Shell technology. Two different dry feeding systems are investigated: the first is a state-of-the- art nitrogen-based lock hopper charger while the second uses CO2 as pressurization gas. The net electric efficiency of the two plants is evaluated as a function of the hydrogen recovery factor (HRF) and the membrane feed pressure in order to minimize the membrane surface area. 90% HRF and 54bar feed pressure are the best operating parameters which correspond to a net electric efficiency of 39% both for N2 and CO2 feeding system. The cost of CO2 avoided is calculated as a function of a parameter named MI which represents the membrane development in terms of performances and costs. Results show that an improvement of membrane technology is necessary to match the state-of-the-art CO2 capture plant, even though membranes show good potentiality for cost abatement

Simulation-supported framework for job shop scheduling with genetic algorithm

The Job Shop Scheduling Problem (JSSP) is recognized to be one of the most difficult scheduling problems, being NP-complete. During years, many different solving techniques were developed: some techniques are focused on the development of optimization algorithms, whilst others are based on simulation models. Since the 80s, it was recognized that a combination of the two could be of big advantage, matching advantages from both sides. However, this research stream has not been followed to a great extent. The goal of this study is to propose a novel scheduling tool able to match these two really different techniques in one common framework in order to fill this gap in literature. The base of the framework is composed by a genetic algorithm (GA) and a simulation model is introduced into the evaluation of the fitness function, due to the inability of GAs in taking into account the real performances of a production system. An additional purpose of this research is to improve the collaboration between academic and industrial worlds on the topic, through an application of the novel scheduling framework to an industrial case. The implementation to the industrial case also suggested an improvement of the tool: The introduction of the stochasticity into the proposed scheduling framework in order to consider the variable nature of the production systems

Synchronisation of material flows in mass-customised production systems: a literature-based classification framework and industrial application

The mass customisation strategy is needed by manufacturing companies to face the increasing variety and unpredictability of products required by customers. However, mass customisation may increase the complexity of managing manufacturing and production logistics activities, for example due to reduced product batch sizes. The synchronisation of material flows within the factory is emerging as a way to address this complexity, as it enables an effective and efficient implementation of mass customisation. Indeed, the fourth Industrial Revolution introduces new digital levers, which can be combined with traditional managerial levers to achieve the synchronisation of material flows within the factory. This study contributes to the rising stream of research on this topic. A systematic literature review was conducted, leading to the development of a classification framework of the levers supporting the synchronisation of material flows. The identified managerial levers are: storage of materials, feeding policy, and scheduling. The digital levers are: materials tracking, process tracking, data analytics, and assistance systems. The developed framework was operationalised in four industrial cases and applied as a tool to map their levers related to the synchronisation of material flows

Economic and environmental impact assessment through system dynamics of technology-enhanced maintenance services

This work presents an economic and environmental impact assessment of maintenance services in order to evaluate how they contribute to sustainable value creation through field service delivery supported by advanced technologies. To this end, systems dynamics is used to assist the prediction of economic and environmental impacts of maintenance services supported by the use of an e-maintenance platform implementing prognosis and health management. A special concern is given to the energy use and related carbon footprint as environmental impacts