14,677 research outputs found
The path to glory untold
A philosophical view of the development of the universe and mans' place in developing his cultural conditions are presented. The effects of population growth on the ecology are analyzed. Propositions for improving the conditions of mankind are presented. The influence of cybernation and automation on the development of space exploration are described
Effect of Particle-Hole Asymmetry on the Mott-Hubbard Metal-Insulator Transition
The Mott-Hubbard metal-insulator transition is one of the most important
problems in correlated electron systems. In the past decade, much progress has
been made on examining a particle-hole symmetric form of the transition in the
Hubbard model with dynamical mean field theory where it was found that the
electronic self energy develops a pole at the transition. We examine the
particle-hole asymmetric metal-insulator transition in the Falicov-Kimball
model, and find that a number of features change when the noninteracting
density of states has a finite bandwidth. Since, generically particle-hole
symmetry is broken in real materials, our results have an impact on
understanding the metal-insulator transition in real materials.Comment: 5 pages, 3 figure
Cumulant expansion of the periodic Anderson model in infinite dimension
The diagrammatic cumulant expansion for the periodic Anderson model with
infinite Coulomb repulsion () is considered here for an hypercubic
lattice of infinite dimension (). The same type of simplifications
obtained by Metzner for the cumulant expansion of the Hubbard model in the
limit of , are shown to be also valid for the periodic Anderson
model.Comment: 13 pages, 7 figures.ps. To be published in J. Phys. A: Mathematical
and General (1997
Current Federal and State Policy Issues Pertaining to Verizon Communications and Broadband Deployment in Massachusetts
This background briefing paper was drafted by the Massachusetts Technology
Collaborative to help the Mass Broadband Initiative advisory committee understand the context
of several important regulatory issues affecting Verizon and its competitors, not only in
Massachusetts but in the country as a whole. These issues have taken on added importance as the
current economic downturn has led to the bankruptcy or downsizing of many Competitive Local
Exchange Carriers (CLECs), which were established to compete directly with Verizon and the
other Baby Bells (Qwest, BellSouth, and SBC Communications).
The troubles in the CLEC industry have rippled back into the telecommunications
equipment industry (including companies in Massachusetts), and have raised the bar for local
Internet access projects (such as those represented on our Mass Broadband Initiative advisory
committee), which are organized to create facilities-based competition at the local level
Fuzzy Modeling and Parallel Distributed Compensation for Aircraft Flight Control from Simulated Flight Data
A method is described that combines fuzzy system identification techniques with Parallel Distributed Compensation (PDC) to develop nonlinear control methods for aircraft using minimal a priori knowledge, as part of NASAs Learn-to-Fly initiative. A fuzzy model was generated with simulated flight data, and consisted of a weighted average of multiple linear time invariant state-space cells having parameters estimated using the equation-error approach and a least-squares estimator. A compensator was designed for each subsystem using Linear Matrix Inequalities (LMI) to guarantee closed-loop stability and performance requirements. This approach is demonstrated using simulated flight data to automatically develop a fuzzy model and design control laws for a simplified longitudinal approximation of the F-16 nonlinear flight dynamics simulation. Results include a comparison of flight data with the estimated fuzzy models and simulations that illustrate the feasibility and utility of the combined fuzzy modeling and control approach
A generalization of moderated statistics to data adaptive semiparametric estimation in high-dimensional biology
The widespread availability of high-dimensional biological data has made the
simultaneous screening of numerous biological characteristics a central
statistical problem in computational biology. While the dimensionality of such
datasets continues to increase, the problem of teasing out the effects of
biomarkers in studies measuring baseline confounders while avoiding model
misspecification remains only partially addressed. Efficient estimators
constructed from data adaptive estimates of the data-generating distribution
provide an avenue for avoiding model misspecification; however, in the context
of high-dimensional problems requiring simultaneous estimation of numerous
parameters, standard variance estimators have proven unstable, resulting in
unreliable Type-I error control under standard multiple testing corrections. We
present the formulation of a general approach for applying empirical Bayes
shrinkage approaches to asymptotically linear estimators of parameters defined
in the nonparametric model. The proposal applies existing shrinkage estimators
to the estimated variance of the influence function, allowing for increased
inferential stability in high-dimensional settings. A methodology for
nonparametric variable importance analysis for use with high-dimensional
biological datasets with modest sample sizes is introduced and the proposed
technique is demonstrated to be robust in small samples even when relying on
data adaptive estimators that eschew parametric forms. Use of the proposed
variance moderation strategy in constructing stabilized variable importance
measures of biomarkers is demonstrated by application to an observational study
of occupational exposure. The result is a data adaptive approach for robustly
uncovering stable associations in high-dimensional data with limited sample
sizes
Discrete Hubbard-Stratonovich transformations for systems with orbital degeneracy
A discrete Hubbard-Stratonovich transformation is presented for systems with
an orbital degeneracy and a Hubbard Coulomb interaction without multiplet
effects. An exact transformation is obtained by introducing an external field
which takes values. Alternative approximate transformations are
presented, where the field takes fewer values, for instance two values
corresponding to an Ising spin.Comment: 4 pages, revtex, 1 eps figure, additional material avalable at
http://librix.mpi-stuttgart.mpg.de/docs/ANDERSEN/fullerene
A case-control study of drug risk factors for age-related macular degeneration.
OBJECTIVE: To investigate the association between age-related macular degeneration (AMD) and exposure to antacids, antithyroids, thyroid hormones, and thiazide diuretics. DESIGN: Matched case-control study. PARTICIPANTS: Population-based participants were selected from the United Kingdom General Practice Research Database. A total of 18,007 people with diagnosed AMD were compared with 86 169 controls matched for age, gender, and general practice. METHODS: Conditional logistic regression was used to determine the association between exposure to each drug group of interest and a diagnosis of AMD, adjusting for relevant confounding variables. MAIN OUTCOME MEASURES: The primary outcome was the odds ratio for the association between exposure to antacids, antithyroids, thyroid hormones, or thiazide diuretics and AMD. Secondary analyses were conducted to assess the effect of recent exposure to the drugs of interest, the total number of prescriptions received, and restricting the data set to participants with more than 2 years of observation time. RESULTS: The crude odds ratios for association between any record of drug exposure and AMD were as follows: 1.34 (95% confidence interval [CI], 1.29-1.39) for antacids; 1.15 (95% CI, 0.92-1.44) for antithyroids; 1.34 (95% CI, 1.29-1.39) for thyroid hormones; and 1.13 (95% CI, 1.08-1.17) for thiazide diuretics. After adjusting for consultation rate, observation time, diabetes, heart failure, hyperlipidemia, cardiovascular drug use, atherosclerosis, hypertension, aspirin use, hormone replacement therapy use, body mass index, alcohol consumption, and smoking, the odds ratios reduced to: 1.06 (95% CI, 1.02-1.10) for antacids, 0.98 (95% CI, 0.78-1.24) for antithyroids, 0.99 (95% CI, 0.92-1.06) for thyroid hormones, and 0.98 (95% CI, 0.94-1.02) for thiazides. Secondary analyses were consistent with these findings for all 4 drug categories. CONCLUSIONS: No association was detected between short- and medium-term use of antithyroids, thyroid hormones, and thiazide diuretics and the risk of AMD. Short- and medium-term use of antacids seems to be associated with a small increase in the risk of this disease. However, this increased risk is likely the result of residual confounding by smoking or uncontrolled confounding resulting from socioeconomic status. No conclusions could be drawn regarding longer-term use of each drug category
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