1,470 research outputs found

    First-order symmetrizable hyperbolic formulations of Einstein's equations including lapse and shift as dynamical fields

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    First-order hyperbolic systems are promising as a basis for numerical integration of Einstein's equations. In previous work, the lapse and shift have typically not been considered part of the hyperbolic system and have been prescribed independently. This can be expensive computationally, especially if the prescription involves solving elliptic equations. Therefore, including the lapse and shift in the hyperbolic system could be advantageous for numerical work. In this paper, two first-order symmetrizable hyperbolic systems are presented that include the lapse and shift as dynamical fields and have only physical characteristic speeds.Comment: 11 page

    Modified ultrafiltration lowers adhesion molecule and cytokine levels after cardiopulmonary bypass without clinical relevance in adults

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    Objective: Cardiac surgery with cardiopulmonary bypass (CPB) results in expression of cytokines and adhesion molecules (AM) with subsequent inflammatory response. The purpose of the study was to evaluate the clinical impact of modified ultrafiltration (MUF) and its efficacy in reducing cytokines and AM following coronary artery bypass grafting (CABG) in adults. Methods: A prospective randomized study of 97 patients undergoing elective CABG was designed. Fifty patients were operated on using normothermic and 47 patients using hypothermic CPB. The normothermic group was subdivided into a group with modified ultrafiltration (n=30) and a group without MUF (n=20). In the hypothermic group 30 patients received MUF compared to 17 patients serving as controls. MUF was instituted after CPB for 15 min through the arterial and venous bypass circuit lines. Cytokines (IL-6, IL-8, TNF-α, IL-2R) and adhesion molecules (sE-selectin, sICAM-1) were measured preoperatively, pre-MUF, in the ultrafiltrate, 24 h, 48 h and 6 days after surgery by chemiluminescent enzyme immunometric assay or enzyme-linked immunosorbent assay (ELISA). Clinical parameters were collected prospectively until discharge. Results: In all patients AM and cytokines were significantly elevated after normothermic and hypothemic CPB. AM and cytokines were significantly higher in hypothermia compared to normothermia. In hypothermic CPB sE-selectin was decreased after 24 h by 37% (P<0.0063) and by 40% (P<0.0027) after 48 h postoperatively. ICAM-1 was reduced by 43% (P<0.0001) after 24 h and by 60% (P<0.0001) after 6 days. Similar results were seen in cytokines with reduction up to 60% after 24 h. Changes after 48 h were noticeable but not significant. Reduction of AM and cytokines after normothermic CPB was minimal. Neither in normothermia, nor in hypothermia has sIL-2R been effectively removed from the circulation. There were no significant differences in the clinical variables between the patients with or without MUF. Conclusion: AM and cytokines are significantly elevated after hypothermic CPB compared to normothermic CPB. MUF led to a significant reduction in cytokine and AM levels after hypothermic CPB, except for IL-2R. MUF showed minimal effect in normothermia. We conclude that MUF is an efficient way to remove cytokines and AM. However, we were unable to demonstrate any significant impact of MUF in outcome of adults after elective CAB

    The Cauchy Problem for the Einstein Equations

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    Various aspects of the Cauchy problem for the Einstein equations are surveyed, with the emphasis on local solutions of the evolution equations. Particular attention is payed to giving a clear explanation of conceptual issues which arise in this context. The question of producing reduced systems of equations which are hyperbolic is examined in detail and some new results on that subject are presented. Relevant background from the theory of partial differential equations is also explained at some lengthComment: 98 page

    Symmetric hyperbolic system in the Ashtekar formulation

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    We present a first-order symmetric hyperbolic system in the Ashtekar formulation of general relativity for vacuum spacetime. We add terms from constraint equations to the evolution equations with appropriate combinations, which is the same technique used by Iriondo, Leguizam\'on and Reula [Phys. Rev. Lett. 79, 4732 (1997)]. However our system is different from theirs in the points that we primarily use Hermiticity of a characteristic matrix of the system to characterize our system "symmetric", discuss the consistency of this system with reality condition, and show the characteristic speeds of the system.Comment: 4 pages, RevTeX, to appear in Phys. Rev. Lett., Comments added, refs update

    Algebraic stability analysis of constraint propagation

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    The divergence of the constraint quantities is a major problem in computational gravity today. Apparently, there are two sources for constraint violations. The use of boundary conditions which are not compatible with the constraint equations inadvertently leads to 'constraint violating modes' propagating into the computational domain from the boundary. The other source for constraint violation is intrinsic. It is already present in the initial value problem, i.e. even when no boundary conditions have to be specified. Its origin is due to the instability of the constraint surface in the phase space of initial conditions for the time evolution equations. In this paper, we present a technique to study in detail how this instability depends on gauge parameters. We demonstrate this for the influence of the choice of the time foliation in context of the Weyl system. This system is the essential hyperbolic part in various formulations of the Einstein equations.Comment: 25 pages, 5 figures; v2: small additions, new reference, publication number, classification and keywords added, address fixed; v3: update to match journal versio

    Collaboration scripts - a conceptual analysis

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    This article presents a conceptual analysis of collaboration scripts used in face-to-face and computer-mediated collaborative learning. Collaboration scripts are scaffolds that aim to improve collaboration through structuring the interactive processes between two or more learning partners. Collaboration scripts consist of at least five components: (a) learning objectives, (b) type of activities, (c) sequencing, (d) role distribution, and (e) type of representation. These components serve as a basis for comparing prototypical collaboration script approaches for face-to-face vs. computer-mediated learning. As our analysis reveals, collaboration scripts for face-to-face learning often focus on supporting collaborators in engaging in activities that are specifically related to individual knowledge acquisition. Scripts for computer-mediated collaboration are typically concerned with facilitating communicative-coordinative processes that occur among group members. The two lines of research can be consolidated to facilitate the design of collaboration scripts, which both support participation and coordination, as well as induce learning activities closely related to individual knowledge acquisition and metacognition. In addition, research on collaboration scripts needs to consider the learners’ internal collaboration scripts as a further determinant of collaboration behavior. The article closes with the presentation of a conceptual framework incorporating both external and internal collaboration scripts

    Competition between Ferrimagnetism and Magnetic Frustration in Zinc Substituted YBaFe4O7

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    The substitution of zinc for iron in YBaFe4O7 has allowed the oxide series YBaFe4-xZnxO7, with 0.40 < x < 1.50, belonging to the "114" structural family to be synthesized. These oxides crystallize in the hexagonal symmetry (P63mc), as opposed to the cubic symmetry (F-43m) of YBaFe4O7. Importantly, the d.c. magnetization shows that the zinc substitution induces ferrimagnetism, in contrast to the spin glass behaviour of YBaFe4O7. Moreover, a.c. susceptibility measurements demonstrate that concomitantly these oxides exhibit a spin glass or a cluster glass behaviour, which increases at the expense of ferrimagnetism, as the zinc content is increased. This competition between ferrimagnetism and magnetic frustration is interpreted in terms of lifting of the geometric frustration, inducing the magnetic ordering, and of cationic disordering, which favours the glassy state.Comment: 24 pages, 10 figure

    Prospects for the CERN Axion Solar Telescope Sensitivity to 14.4 keV Axions

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    The CERN Axion Solar Telescope (CAST) is searching for solar axions using the 9.0 T strong and 9.26 m long transverse magnetic field of a twin aperture LHC test magnet, where axions could be converted into X-rays via reverse Primakoff process. Here we explore the potential of CAST to search for 14.4 keV axions that could be emitted from the Sun in M1 nuclear transition between the first, thermally excited state, and the ground state of 57Fe nuclide. Calculations of the expected signals, with respect to the axion-photon coupling, axion-nucleon coupling and axion mass, are presented in comparison with the experimental sensitivity.Comment: 4 pages, 1 figure. Submitted to Nucl. Instr. and Meth.

    CAST constraints on the axion-electron coupling

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    In non-hadronic axion models, which have a tree-level axion-electron interaction, the Sun produces a strong axion flux by bremsstrahlung, Compton scattering, and axio-recombination, the "BCA processes." Based on a new calculation of this flux, including for the first time axio-recombination, we derive limits on the axion-electron Yukawa coupling g_ae and axion-photon interaction strength g_ag using the CAST phase-I data (vacuum phase). For m_a < 10 meV/c2 we find g_ag x g_ae< 8.1 x 10^-23 GeV^-1 at 95% CL. We stress that a next-generation axion helioscope such as the proposed IAXO could push this sensitivity into a range beyond stellar energy-loss limits and test the hypothesis that white-dwarf cooling is dominated by axion emission
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