Lung Cancer and Epigenetic Modifications | Akciğer Kanseri Ve Epigenetik Değişiklikler

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TOXICITY-CHEMISTRY RELATIONSHIPS IN SEDIMENTS COLLECTED FROM BLACK SEA

Abstract This research investigated the spatial distribution of chemical contamination and toxicity of marine surfacial sediments collected from six sites along the Turkish coast in Black Sea. Sediment toxicity to sea urchin (Paracentrotus lividus) embryonic development was evaluated with whole sediment specimens. Concurrently, sediment samples were analyzed for their chemical characterisation to evaluate toxicity data

Evaluation of liver damage after application of TVE in the rat model

WOS: 000234412900103PubMed: 16387167Introduction. The aim of this study was to investigate the effects of total vascular exclusion (TVE) on the liver during the early period of reperfusion. Materials and methods. Forty Wistar-Albino rats were divided into four groups. Portal pedicle clamping (groups 1 and 2) or TVE (groups 3 and 4) were applied for 10 minutes. Samples were collected at the time of clamp release (groups 1 and 3) and at 30 minutes of reperfusion (groups 2 and 4). We examined oxidative injury to and histopathology of the liver. Results. Oxidative stress was more prominent with TVE application. Significant alterations were shown in hepatic superoxide dismutase, catalase, glutathione, and glutathione S-transferase levels. The levels of malondialdehyde and myeloperoxidase were not altered significantly. Conclusion. Inflow-outflow occlusion of the liver causes more oxidative stress compared with inflow occlusion