48 research outputs found
Electron-hole asymmetry is the key to superconductivity
In a solid, transport of electricity can occur via negative electrons or via
positive holes. In the normal state of superconducting materials experiments
show that transport is usually dominated by
. Instead, in the superconducting state experiments show that the
supercurrent is always carried by .
These experimental facts indicate that electron-hole asymmetry plays a
fundamental role in superconductivity, as proposed by the theory of hole
superconductivity.Comment: Presented at the New3SC-4 meeting, San Diego, Jan. 16-21 2003; to be
published in Int. J. Mod. Phys.
Why holes are not like electrons. II. The role of the electron-ion interaction
In recent work, we discussed the difference between electrons and holes in
energy band in solids from a many-particle point of view, originating in the
electron-electron interaction, and argued that it has fundamental consequences
for superconductivity. Here we discuss the fact that there is also a
fundamental difference between electrons and holes already at the single
particle level, arising from the electron-ion interaction. The difference
between electrons and holes due to this effect parallels the difference due to
electron-electron interactions: {\it holes are more dressed than electrons}. We
propose that superconductivity originates in 'undressing' of carriers from
electron-electron and electron-ion interactions, and that both aspects
of undressing have observable consequences.Comment: Continuation of Phys.Rev.B65, 184502 (2002) = cond-mat/0109385 (2001
MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis
Commitment of progenitors in the dermomyotome to myoblast fate is the first step in establishing the body musculature. Pax3 is a crucial transcription factor, important for skeletal muscle development and expressed in myogenic progenitors in the dermomyotome of developing somites and in migratory muscle progenitors that populate the limb buds. Down-regulation of Pax3 is essential to ignite the myogenic program, including up-regulation of myogenic regulators, Myf-5 and MyoD. MicroRNAs (miRNAs) confer robustness to developmental timing by posttranscriptional repression of genetic programs that are related to previous developmental stages or to alternative cell fates. Here we demonstrate that the muscle-specific miRNAs miR-1 and miR-206 directly target Pax3. Antagomir-mediated inhibition of miR-1/miR-206 led to delayed myogenic differentiation in developing somites, as shown by transient loss of myogenin expression. This correlated with increased Pax3 and was phenocopied using Pax3-specific target protectors. Loss of myogenin after antagomir injection was rescued by Pax3 knockdown using a splice morpholino, suggesting that miR-1/miR-206 control somite myogenesis primarily through interactions with Pax3. Our studies reveal an important role for miR-1/miR-206 in providing precision to the timing of somite myogenesis. We propose that posttranscriptional control of Pax3 downstream of miR-1/miR-206 is required to stabilize myoblast commitment and subsequent differentiation. Given that mutually exclusive expression of miRNAs and their targets is a prevailing theme in development, our findings suggest that miRNA may provide a general mechanism for the unequivocal commitment underlying stem cell differentiation
Towards an understanding of hole superconductivity
From the very beginning K. Alex M\"uller emphasized that the materials he and
George Bednorz discovered in 1986 were superconductors. Here I would
like to share with him and others what I believe to be key reason for why
high cuprates as well as all other superconductors are hole
superconductors, which I only came to understand a few months ago. This paper
is dedicated to Alex M\"uller on the occasion of his 90th birthday.Comment: Dedicated to Alex M\"uller on the Occasion of his 90th Birthday.
arXiv admin note: text overlap with arXiv:1703.0977
Superconductivity from Undressing
Photoemission experiments in high cuprates indicate that quasiparticles
are heavily 'dressed' in the normal state, particularly in the low doping
regime. Furthermore these experiments show that a gradual undressing occurs
both in the normal state as the system is doped and the carrier concentration
increases, as well as at fixed carrier concentration as the temperature is
lowered and the system becomes superconducting. A similar picture can be
inferred from optical experiments. It is argued that these experiments can be
simply understood with the single assumption that the quasiparticle dressing is
a function of the local carrier concentration. Microscopic Hamiltonians
describing this physics are discussed. The undressing process manifests itself
in both the one-particle and two-particle Green's functions, hence leads to
observable consequences in photoemission and optical experiments respectively.
An essential consequence of this phenomenology is that the microscopic
Hamiltonians describing it break electron-hole symmetry: these Hamiltonians
predict that superconductivity will only occur for carriers with hole-like
character, as proposed in the theory of hole superconductivity
Bilateral multifocal Warthin's tumors in upper neck lymph nodes. report of a case and brief review of the literature
Cystadenolymphomas (Warthin's tumors) are the second most frequent lesions of the parotid gland. Due to their benign clinical behavior, the low rates of recurrence and malignant transformation they were classified as tumor-like lesions. In addition, a polyclonal growth of the epithelial components of the tumor could be detected. Warthin's tumors occur bilateral in 7-10%, whereas a multifocal appearance is extremely rare. Even if the pathogenesis is still unclear a heterotopia of salivary tissue during embryogenesis is the most likely explanation for the origin of these tumors in the upper neck and periparotideal region. Here we present a rare case of bilateral, multifocal, extraglandular Warthin's tumors in lymph nodes of the upper neck and give a brief review of the literature. If a primary malignancy can be excluded by a careful staging procedure prior to the operation an isolated excision of the lesions of the neck is the adequate treatment
Effect of orbital relaxation on the band structure of cuprate superconductors and implications for the superconductivity mechanism
Use of the Optimata Virtual Patient (OVP) to predict effects of sunitinib malate in advanced pancreatic cancer.
Preparation of the extracellular domain of the rabbit prolactin receptor expressed in Escherichia coli and its interaction with lactogenic hormones
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