Should we consider Dupuytren's contracture as work-related? A review and meta-analysis of an old debate

International audienceABSTRACT: BACKGROUND: In view of the conflicting opinions published, a meta-analysis was undertaken on epidemiological studies in order to assess any association between Dupuytren's contracture and work exposure. METHODS: Using the key words: "occupational disease", "work" and "Dupuytren contracture" without limitation on language or year of publication, epidemiological studies were selected from four databases (Pub-Med, Embase, Web of science, BDSP) after two rounds (valid control group, valid work exposure). A quality assessment list was constructed and used to isolate papers with high quality methodological criteria (scores of 13 or above, HQMC). Relevant associations between manual work, vibration exposure (at work) and Dupuytren's contracture were extracted from the articles and a metarisk calculated using the generic variance approach (meta-odds ratios, meta-OR). RESULTS: From 1951 to 2007, 14 epidemiological studies (including 2 cohort studies, 3 case-control studies, and 9 cross-sectional studies/ population surveys) were included. Two different results could be extracted from five studies (based on different types of exposure), leading to 19 results, 12 for manual work (9 studies), and 7 for vibration exposure (5 studies). Six studies met the HQMC, yielding 9 results, 5 for manual work and 4 for vibration exposure. Five studies found a dose-response relationship. The meta-OR for manual work was 2.02[1.57;2.60] (HQMC studies only: 2.01[1.51;2.66]), and the meta-OR for vibration exposure was 2.88 [1.36;6.07] (HQMC studies only: 2.14[1.59;2.88]). CONCLUSION: These results support the hypothesis of an association between high levels of work exposure (manual work and vibration exposure) and Dupuytren's contracture in certain cases

VALEUR ALIMENTAIRE DE LA FARINE DE BANANE ET DE MANIOC DANS LE RÉGIME DU PORCELET SEVRÉ A 5 SEMAINES : INFLUENCE DU TAUX DE PROTÉINES DE LA RATION

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VALEUR ÉNERGÉTIQUE ET AZOTÉE DE VIGNA SINENSIS POUR LE PORC : EFFET DE LA CUISSON ET COMPARAISON AVEC LE TOURTEAU DE SOJA

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Reinventing American Protestantism: Christianity in the new millennium

During the past thirty years the American religious landscape has undergone a dramatic change. More and more churches meet in converted warehouses, many have ministers who've never attended a seminary, and congregations are singing songs whose melodies might be heard in bars or nightclubs. Donald E. Miller's provocative examination of these "new paradigm churches" - sometimes called megachurches or postdenominational churches shows how they are reinventing the way Christianity is experienced in the United States today.Drawing on over five years of research and hundreds of interviews, Miller explores three of the movements that have created new paradigm churches: Calvary Chapel, Vineyard Christian Fellowship, and Hope Chapel. Together, these groups have over one thousand congregations and are growing rapidly, attracting large numbers of worshipers who have felt alienated from institutional religion. While attempting to reconnect with first-century Christianity, these churches meet in nonreligious structures and use the medium of contemporary twentieth-century America to spread their message through contemporary forms of worship, Christian rock music, and a variety of support and interest groups.In the first book to examine postdenominational churches in depth, Miller argues that these churches are involved in a second Reformation, one that challenges the bureaucracy and rigidity of mainstream Christianity. The religion of the new millennium, says Miller, will connect people to the sacred by reinventing traditional worship and redefining the institutional forms associated with denominational Christian churches. Nothing less than a transformation of religion in the United States may be taking place, and Miller convincingly demonstrates how "postmodern traditionalists" are at the forefront of this change

Norman D. Nevills flying his Piper J3 airplane "Cherry II" from Kayenta, Arizona to Mexican Hat, Utah, April 23, 1949.

Photo shows Norman D. Nevills and his Piper J3 Cub airplane "Cherry II," flying over the Mexican Hat area, southern Utah;Caption on back of photograph: "Subject: Norman Nevills and Ice cream