Tyrosine hydroxylase neurons in the male hamster chemosensory pathway contain androgen receptors and are influenced by gonadal hormones

Chemosensory and hormonal signals, both of which are essential for mating in the male Syrian hamster, are relayed through a distinct forebrain circuit. Immunocytochemistry for tyrosine hydroxylase, a catecholamine biosynthetic enzyme, previously revealed immunoreactive neurons in the anterior and posterior medial amygdaloid nucleus, one of the nuclei within this pathway. In addition, dopamine-immunoreactive neurons were located in the posterior, but not hte anterior, medial amygdala. In the present study, tyrosine hydroxylase-immunostained neurons were also observed in other areas of the chemosensory pathway, including the posteromedial bed nucleus of the stria terminalis and the posterior, lateral part of the medial preoptic area, while dopamine immunostaining was only seen in the posteromedial bed nucleus of the stria terminalis. The colocalization of tyrosine hydroxylase and androgen receptors was examined in these four tyrosine hydroxylase cell groups by a double immunoperoxidase technique. The percentage of tyrosine hydroxylase-immunolabeled neurons that were also androgen receptor-immunoreactive was highest in the posterior medial amygdaloid nucleus (74%) and the bed nucleus of the stria terminalis (79%). Fewer tyrosine hydroxylase-immunostained neurons in the anterior medial amygdala (33%) and the medial preoptic area (4%) contained androgen receptors. Surprisingly, castration resulted in a significant decrease in the number of tyrosine hydroxylase-immunoreactive neurons only in the anterior medial amygdaloid nucleus, and this effect was transient. Six weeks after castratio, the anterior medial amygdala contained 61% fewer tyrosine hydroxylase-immunolabeled neurons, but 12 weeks after gonadectomy, immunostaining returned to intact values. The number of immunostained neurons in testosterone-replaced, castrated hamsters was not significantly different from that of intact or castrated animals at any time. The results of this study indicate that a substantial number of tyrosine hydroxylase-immunostained neurons in the chemosensory pathway are influenced by androgens; the majority of these neurons in the posterior medial amygdala and the posteromedial bed nucleus of the stria terminalis produce androgen receptors, and tyrosine hydroxylase immunoreactivity is altered by castration in the anterior medial amygdala. © 1993 Wiley-Liss, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50056/1/903310402_ftp.pd

NGC 1068: No change in the mid-IR torus structure despite X-ray variability

Context. Recent NuSTAR observations revealed a somewhat unexpected increase in the X-ray flux of the nucleus of NGC 1068. We expect the infrared emission of the dusty torus to react on the intrinsic changes of the accretion disk. Aims. We aim to investigate the origin of the X-ray variation by investigating the response of the mid-infrared environment. Methods. We obtained single-aperture and interferometric mid-infrared measurements and directly compared the measurements observed before and immediately after the X-ray variations. The average correlated and single-aperture fluxes as well as the differential phases were directly compared to detect a possible change in the structure of the nuclear emission on scales of $\sim$ 2 pc. Results. The flux densities and differential phases of the observations before and during the X-ray variation show no significant change over a period of ten years. Possible minor variations in the infrared emission are $\lesssim$ 8 %. Conclusions. Our results suggest that the mid-infrared environment of NGC 1068 has remained unchanged for a decade. The recent transient change in the X-rays did not cause a significant variation in the infrared emission. This independent study supports previous conclusions that stated that the X-ray variation detected by NuSTAR observations is due to X-ray emission piercing through a patchy section of the dusty region.Comment: 6 pages, 5 figures, 3 tables. Accepted for publication on A&

Ram pressure and dusty red galaxies - key factors in the evolution of the multiple cluster system Abell 901/902

We present spectroscopic observations of 182 disk galaxies (96 in the cluster and 86 in the field environment) in the region of the Abell 901/902 multiple cluster system, which is located at a redshift of $z\sim 0.165$. The presence of substructures and non-Gaussian redshift distributions indicate that the cluster system is dynamically young and not in a virialized state. We find evidence for two important galaxy populations. \textit{Morphologically distorted galaxies} are probably subject to increased tidal interactions. They show pronounced rotation curve asymmetries at intermediate cluster-centric radii and low rest-frame peculiar velocities. \textit{Morphologically undistorted galaxies} show the strongest rotation curve asymmetries at high rest-frame velocities and low cluster-centric radii. Supposedly, this group is strongly affected by ram-pressure stripping due to interaction with the intra-cluster medium. Among the morphologically undistorted galaxies, dusty red galaxies have particularly strong rotation curve asymmetries, suggesting ram pressure is an important factor in these galaxies. Furthermore, dusty red galaxies on average have a bulge-to-total ratio higher by a factor of two than cluster blue cloud and field galaxies. The fraction of kinematically distorted galaxies is 75% higher in the cluster than in the field environment. This difference mainly stems from morphological undistorted galaxies, indicating a cluster-specific interaction process that only affects the gas kinematics but not the stellar morphology. Also the ratio between gas and stellar scale length is reduced for cluster galaxies compared to the field sample. Both findings could be best explained by ram-pressure effects.Comment: Electronic version published in Astronomy and Astrophysics Volume 549, Page 0; 19 pages, 21 figure

Tully-Fisher analysis of the multiple cluster system Abell 901/902

We derive rotation curves from optical emission lines of 182 disk galaxies (96 in the cluster and 86 in the field) in the region of Abell 901/902 located at $z\sim 0.165$. We focus on the analysis of B-band and stellar-mass Tully-Fisher relations. We examine possible environmental dependencies and differences between normal spirals and "dusty red" galaxies, i.e. disk galaxies that have red colors due to relatively low star formation rates. We find no significant differences between the best-fit TF slope of cluster and field galaxies. At fixed slope, the field population with high-quality rotation curves (57 objects) is brighter by \Delta M_{B}=-0\fm42\pm0\fm15 than the cluster population (55 objects). We show that this slight difference is at least in part an environmental effect. The scatter of the cluster TFR increases for galaxies closer to the core region, also indicating an environmental effect. Interestingly, dusty red galaxies become fainter towards the core at given rotation velocity (i.e. total mass). This indicates that the star formation in these galaxies is in the process of being quenched. The luminosities of normal spiral galaxies are slightly higher at fixed rotation velocity for smaller cluster-centric radii. Probably these galaxies are gas-rich (compared to the dusty red population) and the onset of ram-pressure stripping increases their star-formation rates. The results from the TF analysis are consistent with and complement our previous findings. Dusty red galaxies might be an intermediate stage in the transformation of infalling field spiral galaxies into cluster S0s, and this might explain the well-known increase of the S0 fraction in galaxy clusters with cosmic time.Comment: Accepted for publication in Astronomy and Astrophysics; 16 pages, 14 figure

Spectroscopic and photometric oscillatory envelope variability during the S Doradus outburst of the Luminous Blue Variable R71

To better understand the LBV phenomenon, we analyze multi-epoch and multi-wavelength spectra and photometry of R71. Pre-outburst spectra are analyzed with the radiative transfer code CMFGEN to determine the star's fundamental stellar parameters. During quiescence, R71 has an effective temperature of $T_\mathrm{{eff}} = 15\,500~K$ and a luminosity of log$(L_*/L_{\odot})$ = 5.78 and is thus a classical LBV, but at the lower luminosity end of this group. We determine its mass-loss rate to $4.0 \times 10^{-6}~M_{\odot}~$yr$^{-1}$. We present R71's spectral energy distribution from the near-ultraviolet to the mid-infrared during its present outburst. Mid-infrared observations suggest that we are witnessing dust formation and grain evolution. Semi-regular oscillatory variability in the star's light curve is observed during the current outburst. Absorption lines develop a second blue component on a timescale twice that length. The variability may consist of one (quasi-)periodic component with P ~ 425/850 d with additional variations superimposed. During its current S Doradus outburst, R71 occupies a region in the HR diagram at the high-luminosity extension of the Cepheid instability strip and exhibits similar irregular variations as RV Tau variables. LBVs do not pass the Cepheid instability strip because of core evolution, but they develop comparable cool, low-mass, extended atmospheres in which convective instabilities may occur. As in the case of RV Tau variables, the occurrence of double absorption lines with an apparent regular cycle may be due to shocks within the atmosphere and period doubling may explain the factor of two in the lengths of the photometric and spectroscopic cycles.Comment: 18 pages, 14 figures, submitted to A&

Inheritance of soybean resistance to Rotylenchulus reniformis.

Genetic inheritance of soybean resistance to Rotylenchulus reniformis was studied by evaluating the phenotypic reaction of soybean plants to the nematode. The resistant (Forrest and Custer) and susceptible (BR96-25619) soybean cultivars used as parents as well as the F1, F2 and F2:3 derived from their crosses were infested individually with 1,000 eggs and vermiform R. reniformis. About 70 days after the infestation, the nematodes were extracted from the roots and the reproduction factors and the numbers of nematodes per gram of roots were estimated, and data were adjusted for genetic models. Results suggested a predominance of additive genetic effects controlling the nematode resistance reaction. Based on mean and variance genetic models, further genetic gains are expected in the crossing Custer x BR96-25619. The effect of genetic dominance is towards susceptibility. The presence of significant epistasis indicates the existence of at least two genes controlling resistance and that they are interacting. The normal continuous distribution of frequencies of the number of individuals in different classes of resistance indicates that the resistance to the reniform nematode is inherited quantitatively

Spatial matter density mapping of the STAGES Abell A901/2 supercluster field with 3D lensing

We present weak lensing data from the Hubble Space Telescope(HST)/Space Telescope A901/902 Galaxy Evolution Survey (STAGES) survey to study the three-dimensional spatial distribution of matter and galaxies in the Abell 901/902 supercluster complex. Our method improves over the existing 3D lensing mapping techniques by calibrating and removing redshift bias and accounting for the effects of the radial elongation of 3D structures. We also include the first detailed noise analysis of a 3D lensing map, showing that even with deep HST-quality data, only the most massive structures, for example M200≳ 1015M⊙h-1 at z∼ 0.8, can be resolved in 3D with any reasonable redshift accuracy (Δz≈ 0.15). We compare the lensing map to the stellar mass distribution and find luminous counterparts for all mass peaks detected with a peak significance >3σ. We see structures in and behind the z= 0.165 foreground supercluster, finding structure directly behind the A901b cluster at z∼ 0.6 and also behind the south-west (SW) group at z∼ 0.7. This 3D structure viewed in projection has no significant impact on recent mass estimates of A901b or the SW group components SWa and SWb. © 2011 The Authors Monthly Notices of the Royal Astronomical Society © 2011 RAS