Chronique de jurisprudence des droits numériques 2016-2017

Cette nouvelle chronique biennale fait son apparition dans un contexte particulier qu’est celui de l’avènement des droits numériques dans nos sociétés. Les auteurs mettent l’accent sur la consécration de principes directeurs à l’ère du numérique ainsi que sur l’évolution de leurs régimes juridiques, tout en prenant soin de les analyser d’un point de vue critique.This new chronicle, published every two years, makes its appearance in a special context – the advent of digital rights in business and society. The authors focus on the consecration of guiding principles in the digital era as well as on their evolving legal regime and analyse them from a critical point of view

Chronique de jurisprudence des droits numériques 2017-2018

Cette chronique s’inscrit dans le prolongement de la première édition, consacrée à l’avènement des droits numériques dans nos sociétés. Les auteurs mettent l’accent sur la consécration de principes directeurs à l’ère du numérique ainsi que sur l’évolution de leurs régimes juridiques, tout en prenant le soin de les analyser d’un point de vue critique.This chronicle follows on from a previous one which was devoted to the advent of digital rights in our societies. The authors focus on the recognition of general principles with the arrival of the digital era as well as on their evolving legal environment and they analyse them from a critical point of view

Le rapport de la Clinique juridique

International audienc

Chronique de jurisprudence des droits numériques 2016-2017

International audienceThis new chronicle, published every two years, makes its appearance in a special context – the advent of digital rights in business and society. The authors focus on the consecration of guiding principles in the digital era as well as on their evolving legal regime and analyse them from a critical point of view.Cette nouvelle chronique biennale fait son apparition dans un contexte particulier qu’est celui de l’avènement des droits numériques dans nos sociétés. Les auteurs mettent l’accent sur la consécration de principes directeurs à l’ère du numérique ainsi que sur l’évolution de leurs régimes juridiques, tout en prenant soin de les analyser d’un point de vue critique

Chronique de jurisprudence constitutionnelle française 2019

Désormais traditionnelle dans cette revue, la chronique de jurisprudence constitutionnelle vise à faire un état des lieux annuel des décisions rendues par le Conseil constitutionnel. Sous un angle critique, les auteurs présentent les continuité et rupture de jurisprudence, ainsi que la variabilité du contrôle exercé par le Conseil selon les droits en cause.Now traditional in this journal, the chronicle of constitutional jurisprudence aims to make an annual inventory of the Constitutional Council’s decisions. From a critical point of view, the authors present the continuity and discontinuity of case law, and the variability of the control exercised by the Conseil according to the rights in question

ANTI-DIFFUSIVE ALTERNATE-DIRECTIONS SCHEMES FOR THE TRANSPORT OF STEP FUNCTIONS

The purpose in this paper is to design finite-volumes schemes on structured grids for the transport of piecewise-constant functions (typically, indicator functions) with as low diffusion as possible. We first propose an extension of the so-called Lagrange-projection algorithm, or downwind scheme with an Ultrabee limiter, for the transport equation in one space dimension with a non-constant velocity; as its constant velocity counterpart, this scheme is designed to capture the discontinuities separating two plateaus in only one cell, and is referred to as "anti-diffusive". It is shown to preserve the bounds of the solution. Then, for two and three dimensional problems, we introduce a conservative alternate-directions algorithm, an show that this latter enjoys a discrete maximum principle, provided that the underlying one-dimensional schemes satisfy a property which may be seen as a flux limitation, possibly incorporated a posteriori in any explicit scheme. Numerical tests of this alternate-directions algorithm are performed, with a variety of one-dimensional embedded schemes including the anti-diffusive scheme developed here and the so called THINC scheme. The observed numerical diffusion is indeed very low. With the anti-diffusive scheme, the above-mentionned a posteriori limitation is necessary to preserve the solution bounds, but, in the performed tests, does not introduce any visible additional diffusion

Effet de la souche et de la densité sur le comportement et la santé du poulet de chair élevé en lumière naturelle avec des enrichissements

National audienc

Effect of genotype and stocking density on behavior and health of broiler chickens

International audienc

MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions

Although the genetic basis of mitral valve prolapse (MVP) has now been clearly established, the molecular and cellular mechanisms involved in the pathological processes associated to a specific mutation often remain to be determined. The FLNA gene (encoding Filamin A; FlnA) was the first gene associated to non-syndromic X-linked myxomatous valvular dystrophy, but the impacts of the mutations on its function remain un-elucidated. Here, using the first repeats (1–8) of FlnA as a bait in a yeast two-hybrid screen, we identified the tyrosine phosphatase PTPN12 (PTP-PEST) as a specific binding partner of this region of FlnA protein. In addition, using yeast two-hybrid trap assay pull down and co-immunoprecipitation experiments, we showed that the MVP-associated FlnA mutations (G288R, P637Q, H743P) abolished FlnA/PTPN12 interactions. PTPN12 is a key regulator of signaling pathways involved in cell-extracellular matrix (ECM) crosstalk, cellular responses to mechanical stress that involve integrins, focal adhesion transduction pathways, and actin cytoskeleton dynamics. Interestingly, we showed that the FlnA mutations impair the activation status of two PTPN12 substrates, the focal adhesion associated kinase Src, and the RhoA specific activating protein p190RhoGAP. Together, these data point to PTPN12/FlnA interaction and its weakening by FlnA mutations as a mechanism potentially involved in the physiopathology of FlnA-associated MVP

Motivation for foraging behavior and feed place preference in free-range broiler chickens

International audienc