46 research outputs found
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Geologic and engineering characterization of Geraldine Ford Field, Reeves, and Culberson Counties, Texas - special core-analysis data. Topical report, 1997
This report contains special core analysis data from the Geraldine Ford Field
Geology and geohydrology of the Palo Duro Basin, Texas panhandle : a report on the progress of nuclear waste isolation feasibility studies (1978)
Contract no. EY-77-S-05-5466; ORO/5466-10UT Librarie
Fibroblastic reticular cells provide a supportive niche for lymph nodeâresident macrophages
The lymph node (LN) is home to resident macrophage populations that are essential for immune function and homeostasis, but key factors controlling this niche are undefined. Here, we show that fibroblastic reticular cells (FRCs) are an essential component of the LN macrophage niche. Genetic ablation of FRCs caused rapid loss of macrophages and monocytes from LNs across two in vivo models. Macrophages coâlocalized with FRCs in human LNs, and murine singleâcell RNAâsequencing revealed that FRC subsets broadly expressed master macrophage regulator CSF1. Functional assays containing purified FRCs and monocytes showed that CSF1R signaling was sufficient to support macrophage development. These effects were conserved between mouse and human systems. These data indicate an important role for FRCs in maintaining the LN parenchymal macrophage niche
Global research priorities for sea turtles : informing management and conservation in the 21st century
Over the past 3 decades, the status of sea turtles and the need for their protection to aid population recovery have increasingly captured the interest of government agencies, non-governmental organisations (NGOs) and the general public worldwide. This interest has been matched by increased research attention, focusing on a wide variety of topics relating to sea turtle biology and ecology, together with the interrelations of sea turtles with the physical and natural environments. Although sea turtles have been better studied than most other marine fauna, management actions and their evaluation are often hindered by the lack of data on turtle biology, human–turtle interactions, turtle population status and threats. In an effort to inform effective sea turtle conservation a list of priority research questions was assembled based on the opinions of 35 sea turtle researchers from 13 nations working in fields related to turtle biology and/or conservation. The combined experience of the contributing researchers spanned the globe as well as many relevant disciplines involved in conservation research. An initial list of more than 200 questions gathered from respondents was condensed into 20 metaquestions and classified under 5 categories: reproductive biology, biogeography, population ecology, threats and conservation strategies
Potential natural changes and implications for a UK GDF
A period of one million years following closure has been used by RWMD when considering the
post-closure safety case for a geological disposal facility (GDF). It is during this period that
evolution of the near-field and local geosphere as a result of GDF construction and operation will
be at its most rapid and radioactivity of the emplaced waste will be at their highest levels.
Significant effort has been spent internationally on identifying the many natural processes that
may affect the evolution of the geosphere over this timescale and the contribution of those
processes to GDF performance. The purpose of this report is to identify which processes are
relevant to geosphere evolution in this time period around a generic GDF in the UK. Previous
work has identified tectonic effects, climate change effects, uplift, subsidence, volcanism and
diagenesis as key concerns. The potential impact of each of these processes on a generic UK
GDF, constructed according to a multiple barrier concept and sited at a depth of between 200 and
1000 m in a suitable host rock, is outlined in the following sections: tectonic related uplift and
subsidence; seismicity, tectonic history and volcanism; climate change and glaciation and
weathering and erosion