1,936 research outputs found
Asymptotic Level Density of the Elastic Net Self-Organizing Feature Map
Whileas the Kohonen Self Organizing Map shows an asymptotic level density
following a power law with a magnification exponent 2/3, it would be desired to
have an exponent 1 in order to provide optimal mapping in the sense of
information theory. In this paper, we study analytically and numerically the
magnification behaviour of the Elastic Net algorithm as a model for
self-organizing feature maps. In contrast to the Kohonen map the Elastic Net
shows no power law, but for onedimensional maps nevertheless the density
follows an universal magnification law, i.e. depends on the local stimulus
density only and is independent on position and decouples from the stimulus
density at other positions.Comment: 8 pages, 10 figures. Link to publisher under
http://link.springer.de/link/service/series/0558/bibs/2415/24150939.ht
X-ray photoemission spectroscopy determination of the InN/yttria stabilized cubic-zirconia valence band offset
The valence band offset of wurtzite InN(0001)/yttria stabilized cubic-zirconia (YSZ)(111) heterojunctions is determined by x-ray photoemission spectroscopy to be 1.19±0.17 eV giving a conduction band offset of 3.06±0.20 eV. Consequently, a type-I heterojunction forms between InN and YSZ in the straddling arrangement. The low lattice mismatch and high band offsets suggest potential for use of YSZ as a gate dielectric in high-frequency InN-based electronic devices
Ultra Precise Modular Reaction Wheel Operation for Optical and Radar Satellites
With the new space arena evolving towards serious science and defense missions, the availability of new space avionics with high-end performance is becoming a prerequisite for modern and future satellite missions.
This puts requirements for very accurate speed and torque control of modern reaction wheels used to perform attitude control of modern spacecraft. Nearly vibration free operation (optical payloads) Extremely trum of frequencies Modularity Fast delivery Scalabilit
Using reference-free compressed data structures to analyze sequencing reads from thousands of human genomes.
We are rapidly approaching the point where we have sequenced millions of human genomes. There is a pressing need for new data structures to store raw sequencing data and efficient algorithms for population scale analysis. Current reference-based data formats do not fully exploit the redundancy in population sequencing nor take advantage of shared genetic variation. In recent years, the Burrows-Wheeler transform (BWT) and FM-index have been widely employed as a full-text searchable index for read alignment and de novo assembly. We introduce the concept of a population BWT and use it to store and index the sequencing reads of 2705 samples from the 1000 Genomes Project. A key feature is that, as more genomes are added, identical read sequences are increasingly observed, and compression becomes more efficient. We assess the support in the 1000 Genomes read data for every base position of two human reference assembly versions, identifying that 3.2 Mbp with population support was lost in the transition from GRCh37 with 13.7 Mbp added to GRCh38. We show that the vast majority of variant alleles can be uniquely described by overlapping 31-mers and show how rapid and accurate SNP and indel genotyping can be carried out across the genomes in the population BWT. We use the population BWT to carry out nonreference queries to search for the presence of all known viral genomes and discover human T-lymphotropic virus 1 integrations in six samples in a recognized epidemiological distribution
Addition-Deletion Networks
We study structural properties of growing networks where both addition and
deletion of nodes are possible. Our model network evolves via two independent
processes. With rate r, a node is added to the system and this node links to a
randomly selected existing node. With rate 1, a randomly selected node is
deleted, and its parent node inherits the links of its immediate descendants.
We show that the in-component size distribution decays algebraically, c_k ~
k^{-beta}, as k-->infty. The exponent beta=2+1/(r-1) varies continuously with
the addition rate r. Structural properties of the network including the height
distribution, the diameter of the network, the average distance between two
nodes, and the fraction of dangling nodes are also obtained analytically.
Interestingly, the deletion process leads to a giant hub, a single node with a
macroscopic degree whereas all other nodes have a microscopic degree.Comment: 8 pages, 5 figure
Effect of withdrawal of fusafungine from the market on prescribing of antibiotics and other alternative treatments in Germany:a pharmacovigilance impact study
Boundary-crossing identities for diffusions having the time-inversion property
We review and study a one-parameter family of functional transformations, denoted by (S (β)) β∈ℝ, which, in the case β<0, provides a path realization of bridges associated to the family of diffusion processes enjoying the time-inversion property. This family includes Brownian motions, Bessel processes with a positive dimension and their conservative h-transforms. By means of these transformations, we derive an explicit and simple expression which relates the law of the boundary-crossing times for these diffusions over a given function f to those over the image of f by the mapping S (β), for some fixed β∈ℝ. We give some new examples of boundary-crossing problems for the Brownian motion and the family of Bessel processes. We also provide, in the Brownian case, an interpretation of the results obtained by the standard method of images and establish connections between the exact asymptotics for large time of the densities corresponding to various curves of each family
Rank Statistics in Biological Evolution
We present a statistical analysis of biological evolution processes.
Specifically, we study the stochastic replication-mutation-death model where
the population of a species may grow or shrink by birth or death, respectively,
and additionally, mutations lead to the creation of new species. We rank the
various species by the chronological order by which they originate. The average
population N_k of the kth species decays algebraically with rank, N_k ~ M^{mu}
k^{-mu}, where M is the average total population. The characteristic exponent
mu=(alpha-gamma)/(alpha+beta-gamma)$ depends on alpha, beta, and gamma, the
replication, mutation, and death rates. Furthermore, the average population P_k
of all descendants of the kth species has a universal algebraic behavior, P_k ~
M/k.Comment: 4 pages, 3 figure
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