Economic reasons behind the decline of the Ottoman empire

This study addresses the economic reasons of the decline and fall of the Ottoman Empire. On the contrary to the previous researches, by undertaking both global and domestic developments, the paper examines the decline of the empire from an economical point of perspective. Although international developments such as industrialization in European countries, pressure on the Ottomans in terms of integrating with the world economy, global economic factors like depressions and wars, as well as domestic factors such as weaknesses of the central government in rural areas, traditional style of governing and structure of economic institutions along with demographic characteristics of the empire had great influence on the decline, the main reason is found to be the inability of the empire to adapt itself to the both internal and external changes and not being resilient which resulted in significant economical trauma

Codes

The codes for Quantification of Resiliency for a Quantum Network.</p

Gain-Switched Short Pulse Generation from 1.55 &micro;m InAs/InP/(113)B Quantum Dot Laser Modeled Using Multi-Population Rate Equations

The gain-switching properties of an InAs-InP (113)B quantum dot laser based on multi-population rate equations are examined theoretically in detail to generate shorter pulses with the application of a Gaussian pulse beam to the laser excited state. The numerical results demonstrated that as the homogeneous and the inhomogeneous broadening increase, the differential gain, the gain compression factor, and the threshold current of the excited state decrease while the threshold current of the ground state increases. It was also observed that the contribution of the excited state to gain-switched output pulses depend on not only the value of the inhomogeneous broadening but also the magnitude of the applied current. Additionally, it was found that without an optical beam, the output pulse has a long pulse width due to ground state emissions and the change in the parameters strongly affecting the output. However, under the optical beam, narrow pulses around 26 ps have high peak power owing to the excited state emission generated even at low currents and also the change in the laser parameters having a negligible effect. Finally, the gain-switching characteristics with and without a Gaussian pulse beam are shown to be similar for liner-gain and nonlinear-gain cases except that higher peak power and narrower output pulses are obtained for the linear-gain case

Surgical results of the slipped medial rectus muscle after hang back recession surgery

<b>AIM:</b>To analyze the surgical results of a slipped medial rectus muscle (MRM) after hang back recession surgery for esotropia.<b>METHODS:</b>Twenty-one patients who underwent re-exploration for diagnosed slipped muscle after hang back recession surgery were included in this retrospective study. Dynamic magnetic resonance imaging was performed to identify the location of the slipped muscle. Ocular motility was evaluated with assessment with prism and cover test in gaze at cardinal positions. The operations were performed by the same consultant. Intraoperative forced duction test was performed under general anesthesia. The empty sheath of the slipped MRM was resected and the muscle was advanced to the original insertion site in all patients.<b>RESULTS:</b>The average age of 21 patients who hadconsecutive exotropia with a slipped MRM at the time of presentation was 17.4±5.4y (5-50y). The average duration between the first operation and the diagnosis of the slipped muscle was 25mo (12 to 36mo). The mean follow up after the corrective surgery was 28mo. The mean preoperative adduction limitation in the field of action of the slipped muscle was -2.26 (ranging from -1 to -4). All patients had full adduction postoperatively.<b>CONCLUSION:</b>The diagnosis of the slipped muscle should be confirmed during the strabismus surgery. The slipped muscle may be caused due to insufficient suture and excessive rubbing of the eye. When divergent strabismus is observed after the recession of the MRM, a slipped muscle should be considered in the differential diagnosis

Gain-Switched Short Pulse Generation from 1.55 µm InAs/InP/(113)B Quantum Dot Laser Modeled Using Multi-Population Rate Equations

The gain-switching properties of an InAs-InP (113)B quantum dot laser based on multi-population rate equations are examined theoretically in detail to generate shorter pulses with the application of a Gaussian pulse beam to the laser excited state. The numerical results demonstrated that as the homogeneous and the inhomogeneous broadening increase, the differential gain, the gain compression factor, and the threshold current of the excited state decrease while the threshold current of the ground state increases. It was also observed that the contribution of the excited state to gain-switched output pulses depend on not only the value of the inhomogeneous broadening but also the magnitude of the applied current. Additionally, it was found that without an optical beam, the output pulse has a long pulse width due to ground state emissions and the change in the parameters strongly affecting the output. However, under the optical beam, narrow pulses around 26 ps have high peak power owing to the excited state emission generated even at low currents and also the change in the laser parameters having a negligible effect. Finally, the gain-switching characteristics with and without a Gaussian pulse beam are shown to be similar for liner-gain and nonlinear-gain cases except that higher peak power and narrower output pulses are obtained for the linear-gain case

Comparative evaluation of hesperetin loaded nanoparticles for anticancer activity against C6 glioma cancer cells

WOS: 000457571200002PubMed ID: 30688095The aim of this study was to evaluate anti-cancer properties of hesperetin (Hsp) and hesperetin-loaded poly(lactic-co-glycolic acid) nanoparticles (HspNPs) for glioblastoma treatment. Nanoparticles prepared by single emulsion method had a size of less than 300nm with 70.7 +/- 3.9% reaction yield and 26.4 +/- 1.1% Hsp loading capacity. Treatment of C6 glioma cells with HspNPs for 24 and 48 h resulted in dose- and time-dependent decrease in cell viability, with approximate IC50 of 28 and 21 mu g/mL, respectively (p = .036 for 24 h, p = .025 for 48 h). The percentage of PCNA positive cells decreased to 20% and 10%, respectively, for Hsp- and HspNP-treated cells at concentration of 100 mu g/mL. Treatment with increasing concentrations of HspNPs (25, 50, 75 and 100 mu g/mL) resulted in 9.1-, 7-, 12.5- and 12.7-fold in increase in apoptotic cell number. Optimum doses of Hsp and HspNPs were found to increase oxidative damage in C6 glioma cells. MDA levels, an indicator of lipid peroxidation, were found to be significantly elevated at 75 and 100 mu g/mL exposure concentration of HspNPs with (p = .002) and (p = .018), respectively for 48-h treatment. The results obtained with this study showed biocompatible polymeric nanoparticle systems has great advantages to enhance anti-cancer activity and poor solubility of therapeutic agents. Overall our findings suggest that Hsp-loaded PLGA nanoparticle systems showed significant anti-cancer activity and HspNPs could be used as promising novel anti-cancer agent

A comparative study of 2-chlorophenol, 2,4-dichlorophenol, and 2,4,6-trichlorophenol adsorption onto polymeric, commercial, and carbonaceous adsorbents

<p>In this study, polymeric and carbonaceous type of adsorbents were synthesized and their 2-chlorophenol (2-CP), 2,4-dichlorophenol (2,4-DCP), and 2,4,6-trichlorophenol (2,4,6-TCP) adsorption performances were compared with commercial available XAD-4 resin. Peach stone-based activated carbon (AC) was fabricated by steam activation and porous copolymer of cyanomethyl styrene–divinylbenzene was synthesized by suspension polymerization method. A comparative examination of chlorophenols (CPs) adsorption onto AC, polymeric, and XAD-4 resin was conducted in batch and continuous systems. Zeta potential and potentiometric titration data were analyzed for three adsorbents. The equilibrium data were fitted to the common types of adsorption isotherm and kinetic models. Freundlich model illustrated best fit to the experimental data. The adsorption kinetic obeys the pseudo-second-order model indicating that the chemical sorption is the rate-controlling parameter for chlorophenolic pollutants. The kinetic results also revealed that the rate of uptake is dependent on the acidity and hydrophobicity of CPs and the adsorbents showed excellent removal efficiency toward 2,4,6-TCP. The positive Δ<i>H</i>° and Δ<i>S</i>° values indicated endothermic nature and the increasing randomness at the solid–liquid interface during sorption process. Breakthrough curves obtained from column study revealed that the order of longer column saturation time was obtained as: 2,4,6-TCP > 2,4-DCP > 2-CP.</p