Medetomidine-midazolam association in dogs: a reversible anaesthesic protocol allowing deep sedation

Poncet Cyrill, Bouvy Bernard, Dupré Gilles. Association médétomidine-midazolam chez le chien : un protocole d'anesthésie réversible permettant une sédation poussée. In: Bulletin de l'Académie Vétérinaire de France tome 156 n°2, 2003. pp. 75-77

The past, present, and future of the brain imaging data structure (BIDS)

The Brain Imaging Data Structure (BIDS) is a community-driven standard for the organization of data and metadata from a growing range of neuroscience modalities. This paper is meant as a history of how the standard has developed and grown over time. We outline the principles behind the project, the mechanisms by which it has been extended, and some of the challenges being addressed as it evolves. We also discuss the lessons learned through the project, with the aim of enabling researchers in other domains to learn from the success of BIDS

The past, present, and future of the Brain Imaging Data Structure (BIDS)

The Brain Imaging Data Structure (BIDS) is a community-driven standard for the organization of data and metadata from a growing range of neuroscience modalities. This paper is meant as a history of how the standard has developed and grown over time. We outline the principles behind the project, the mechanisms by which it has been extended, and some of the challenges being addressed as it evolves. We also discuss the lessons learned through the project, with the aim of enabling researchers in other domains to learn from the success of BIDS

A retrospective study of 40 dogs with polyarthritis.

peer reviewedOBJECTIVE: To characterize the epidemiologic, clinical, laboratory, and radiographic findings from dogs with polyarthritis (PA). STUDY DESIGN: Retrospective clinical study. SAMPLE POPULATION: Forty dogs. METHODS: Medical records of 40 dogs with a diagnosis of PA were reviewed. Retrieved data included breed, age at admission, sex, weight, clinical signs, and the results of synovial fluid analysis, complete blood count, serum chemistry profile, urinalysis, serologic screening tests for infectious diseases, and radiographic examination of affected joints. RESULTS: The incidence of PA was 0.37%. Twenty-nine breeds were represented; 16 dogs were male, and 24 were female. Mean body weight was 20.1 +/- 15 kg. The mean age at admission was 5.6 +/- 4 years. Eighty percent of dogs with PA had difficulty or reluctance walking, 35% were lame, 33% had spontaneous vocalization without any obvious reason, 20% had exercise intolerance, 18% were febrile, and 7.5% had an inability to rise or move. Joint pain was identified in 40% of dogs. Synovial fluid color varied from colorless (36%) to yellow-tinged (36%) or hemorrhagic (28%). Synovial fluid mean cell count varied from 10 cells (400x) to 50 cells (1,000x). Leukocytosis occurred in 59% of the dogs and was more frequently identified in dogs with very severe synovial inflammation. Thirty-one percent of affected dogs were anemic. Serum biochemical profiles were considered abnormal in 13% of the dogs. Joint radiography did not identify erosive arthritis. CONCLUSIONS: PA is a common cause of locomotor abnormalities in dogs; however, true lameness and articular pain are not common clinical findings in dogs with PA. CLINICAL RELEVANCE: PA should be considered in the differential diagnosis for all dogs with difficulty walking

Thoracoscopic treatment of bullous emphysema in 3 dogs.

peer reviewedOBJECTIVE: To report thorascopic partial lobectomy for treatment of bullous emphysema in dogs. STUDY DESIGN: Prospective clinical study. ANIMALS: Three dogs with spontaneous pneumothorax. METHODS: Thoracoscopy without pulmonary exclusion was used to identify bulla. The thorascope was introduced into the thorax lateral to the xyphoid process, and instrument portals were made at different levels along the thoracic wall between the third and tenth intercostal spaces. The thorascope was passed through the mediastinum to view the opposite pleural cavity. After identification of bullae, the affected lung was excised using an endoscopic stapler, and the incision line was checked for air leakage. Thoracic drains were used for air aspiration for 2 days after surgery. RESULTS: Bullae were confirmed histologically as emphysematous lesions. Lung inflation did not interfere with identification of bullae or with surgery. All dogs had full recovery without recurrence for 18 to 29 months after surgery. CONCLUSIONS: Identification and ablation of bulla can be performed thoracoscopically without pulmonary exclusion in dogs. CLINICAL RELEVANCE: Thoracoscopy offers several advantages compared with thoracotomy for treatment and diagnosis of idiopathic pneumothorax, including ease of identification of bullae and reduced postoperative pain and morbidity

Volcanic and hydrothermal processes in submarine calderas: the Kulo Lasi example (SW Pacific)

The study area is located at the transition between the northern end of the Tonga Trench and the North Fiji fracture zone, where tectonic movements are reputed to be the fastest in the world. To the southeast of Futuna Island, a broad area of volcanism occurs within a region characterized by a change in the tectonic fabric between a NE-SW oriented volcanic graben and the N-S oriented Alofi ridge. In 2010, the active volcano Kulo Lasi, which represents the most recent volcanic episode in the Futuna area, was discovered in the center of this extensive volcanic zone. Kulo Lasi is a 20 km diameter shield volcano that rises 400 m above the seafloor. It is composed of basaltic to trachy-andesitic lava with no obvious geochemical affinity with the Tonga subduction that occurs 500 km to the east. The central caldera is 5 km in diameter and 300 m deep and is located at a water depth of 1500 m. Diving operations with the submersible Nautile and high-resolution AUV mapping, have revealed the presence of numerous active and inactive hydrothermal fields on the floor and the walls of the caldera. Four tectono-volcanic stages can be distinguished at Kulo Lasi caldera. In stage 1, the shield volcano is built. Annular reverse faults develop at the summit and control circulation of water/rock-dominated hydrothermal fluids and high-temperature alteration of rocks along the nascent normal faults. Mixing of hydrothermal fluids with seawater is favored along normal superficial faults, leading to the formation of low-temperature Fe/Mn mineralization at the summit of the volcano. During stage 2, the caldera collapse, gradually revealing outcrops of the altered and mineralized zones formed during Stage 1. As the magma chamber cools and collapses, less heat is available. As a result, medium to low-temperature (<100 °C) Fe/Si deposits form on the floor of the caldera. In stage 3, refilling and ascent of the magma chamber at depth promote the uplift of a central resurgent dome devoid of recent lava emission. The depth of the magma chamber under the dome is estimated to be 1.6 km. Annular dykes feeding the new lava flows are controlled by the deep reverse faults at the outer rim of the caldera floor. The eruptive events are accompanied by short-lived emission of magmatic fluids, rich in SO2, materialized by the presence of native sulfur depositions on the surface of the most recent lava flows. During stage 4 (present day), black smoker sulfide chimneys, controlled by the deep reverse faults, form at the surface of the most recent lava flows at the outer part of the caldera floor. The fluids emitted result from the mixing of a deep fluid of the water/rock reaction type and of shallow seawater superheated in contact with the hot dykes. Hydrogen is generated during reaction of seawater with the hot dikes and H2 is enriched in the mixed fluids. Active (43°C) siliceous chimneys at the base of the caldera walls and low-temperature vents (6°C) perched on the caldera walls suggests a decrease in the venting temperature at a distance from the floor of the caldera. In chimneys, the sphalerite/pyrrhotite/isocubanite/barite paragenesis, probably linked to the high H2 concentrations in the fluids, indicate unusual reducing conditions for a back-arc. The sulfide mineralization also has unusual trace element concentrations. The concentration in Pb and Ba appears characteristic of back-arc environments while the enrichment in Co, Se, and Sn is more common to mineralization associated with basalt in mature back-arcs and associated with ultramafic rocks on mid ocean ridges