6,529 research outputs found
Complex WKB Analysis of a PT Symmetric Eigenvalue Problem
The spectra of a particular class of PT symmetric eigenvalue problems has
previously been studied, and found to have an extremely rich structure. In this
paper we present an explanation for these spectral properties in terms of
quantisation conditions obtained from the complex WKB method. In particular, we
consider the relation of the quantisation conditions to the reality and
positivity properties of the eigenvalues. The methods are also used to examine
further the pattern of eigenvalue degeneracies observed by Dorey et al. in
[1,2].Comment: 22 pages, 13 figures. Added references, minor revision
Simultaneous optimisation of structural topology and material grading using level set method
Peer reviewedPublisher PD
Beginning of the End of Cost Competitiveness in CEE Countries - Analysis of Dependence between Labor Costs and Internationalization of the Region
In order to exemplify the above econometric model I carried out empirical analysis of the companies listed on the Warsaw Stock Exchange, identifying the companies for which efficiency-seeking is the main internationalization motive. The analysis of internationalization of 26 companies during the years 1990-2010 clearly shows that a significant part of investments is located outside the territory of Poland, in the countries with lower labor costs. This fact confirms that CEE countries will gradually become less and less attractive in terms of costs not only for MNEs from developed countries but also for the companies originating from transition economies.Głównym celem artykułu jest weryfikacja, czy niski poziom kosztów pracy w Europie Środkowej i Wschodniej będący do tej pory jednym z czynników wpływających na konkurencyjność tego regionu pozostanie nim w dłuższej perspektywie czasowej. W pracy na podstawie próby wszystkich państw UE zbadano zależność pomiędzy poziomem internacjonalizacji (stan odpływu BIZ per capita) a kosztami pracy w sektorze przedsiębiorstw i GNP per capita. Analiza regresji potwierdziła istnienie zależności pomiędzy wyżej wymienionymi czynnikami. Oznacza to, że stopniowy wzrost kosztów pracy w państwach Europy Środkowej i Wschodniej prowadził będzie do stopniowego odpływu BIZ z tego regionu do państw bardziej konkurencyjnych kosztowo. W celu egzemplifikacji powyższych zależności w pracy dodatkowo przedstawiono analizę inwestycji zagranicznych polskich spółek notowanych na GPW, z których to 26 dokonało inwwestycji zagranicznych o wyraźnych motywach związanych z obniżeniem kosztów produkcji. Fakt ten potwierdza powolny spadek konkurencyjności kosztowej polskiej gospodarki, tym samym zmusza do poszukiwania nowych rozwiązań instytucjonalnych mogących utrzymać konkurencyjność polskiej gospodarki w długim okresie
Start-to-end modelling of a mode-locked optical klystron free electron laser amplifier
A free electron laser (FEL) in a mode-locked optical klystron (MLOK) configuration is modelled using start-to-end simulations that simulate realistic electron beam acceleration and transport before input into a full three-dimensional FEL simulation code. These simulations demonstrate that the MLOK scheme is compatible with the present generation of radiofrequency accelerator designs. A train of few-optical cycle pulses is predicted with peak powers similar to those of the equivalent conventional FEL amplifier. The role of electron beam energy modulation in these results is explained and the limitations of some simulation codes discussed. It is shown how seeding the FEL interaction using a High Harmonic seed laser can improve the coherence properties of the output
Environmental legacy of pre-Columbian Maya mercury
The Mexico and Central American region has a history of mercury use that began at least two millennia before European colonisation in the 16th century. Archaeologists have reported extensive deposits of cinnabar (HgS) and other mercury materials in ancient human settlements across the region. However, there has been no consideration to date of the environmental legacy of this long history of anthropogenic mercury use. This review begins by synthesising our knowledge of the history and nature of anthropogenic mercury in ancient Mesoamerica based on archaeological data, with a particular focus on the Maya culture of lowland Guatemala, Belize, the Yucatan of Mexico, El Salvador, and Honduras. The Classic Period Maya used mercury for decorative and ceremonial (including funerary) purposes: Cinnabar (HgS) predominantly, but the archaeological record also shows rare finds of elemental mercury (Hg0) in important burial and religious contexts. In this review, we have located and summarised all published data sets collected from (or near) ancient Maya settlements that include environmental mercury measurements. Comparing mercury determinations from pre-Columbian Maya settlements located across the region confirms that seven sites from ten have reported at least one location with mercury concentrations that equal or exceed modern benchmarks for environmental toxicity. The locations with elevated mercury are typically former Maya occupation areas used in the Late Classic Period, situated within large urban settlements abandoned by c. 10th century CE. It is most likely that the mercury detected in buried contexts at Maya archaeological sites is associated with pre-Columbian mercury use, especially of cinnabar. In more complex contexts, where modern biological or specifically anthropogenic inputs are more probable, legacy mercury in the environment will have a more complex, and time transgressive input history. This review identifies current research gaps in our understanding of the long history of Maya mercury use and in the collection of robust total mercury datasets from the Maya world. We identify important areas for future research on the environmental persistence and legacy of mercury, including the need to interpret environment mercury data in the context of mercury exposure and human health at Maya archaeological sites
Characterization of the Photo-emf Response for Laser-Based Ultrasonic Sensing Under Simulated Industrial Conditions
There is a need in myriad manufacturing environments to nondestructively evaluate components and to control processes in real-time. Laser-based ultrasound [1,2], LBU, has the potential to be a robust, reconfigurable, noncontact diagnostic for many industrial applications. A simple and inexpensive semiconductor sensor based on the nonsteady-state photo-induced-electromotive force (photo-emf) effect [3,4], has been demonstrated [5] to be functional under a variety of manufacturing conditions and in probing various materials, including metals, semiconductors, and organics. This device has the potential to remotely sense ultrasound via speckle motion or coherent detection over a reasonable field-of-view, with good bandwidth and detection sensitivity. In addition, the detector can, at the same time, compensate for otherwise deleterious static and dynamic environmental distortions in real-time, including speckle, beam wander, poor-quality optics, and propagation distortions over free-space paths and through multi-mode optical fibers. Such inspection tools can improve the efficiency, yield and performance of various manufacturing processes, including bonds, surface treatments, case hardening, composites, metallurgy, microcrack detection, adhesion, remote temperature and thickness measurements. By performing the inspection on-line and in real-time, the possibility exists for closed-loop, in-process control. This can lead to reduced cost, labor, scrap, and machine downtime in today’s highly competitive markets
Solvent response to fluorine-atom reaction dynamics in liquid acetonitrile
Solvent restructuring and vibrational cooling follow exothermic fluorine-atom reactions in acetonitrile.</p
High intensity exercise decreases IP6K1 muscle content & improves insulin sensitivity in glucose intolerant individuals
Context
Insulin resistance in skeletal muscle contributes to whole body hyperglycaemia and the secondary complications associated with type 2 diabetes. Inositol hexakisphosphate kinase-1 (IP6K1) may inhibit insulin-stimulated glucose transport in this tissue type.
Objective
Muscle and plasma IP6K1 were correlated with two-compartment models of glucose control in insulin-resistant hyperinsulimic individuals. Muscle IP6K1 was also compared following two different exercise trials.
Methods
Nine pre-diabetic [HbA1c; 6.1 (0.2) %)] were recruited to take part in a resting control, a continuous exercise (90% of lactate threshold) and a high-intensity exercise trial (6 x 30 sec sprints). Muscle biopsies were drawn pre- and post each 60-minute trial. A labeled ([6,62H2]glucose) intravenous glucose tolerance test (IVGTT) was performed immediately after the second muscle sample.
Results
Fasting muscle IP6K1 content did not correlate with SI2* (P = 0.961). High-intensity exercise reduced IP6K1 muscle protein and mRNA expression (P = 0.001). There was no effect on protein IP6K1 content following continuous exercise. Akt308 phosphorylation of was significantly greater following high-intensity exercise. Intermittent exercise reduced hepatic glucose production (HGP) following the same trial. The same intervention also improved SI2* and this was significantly greater compared to the continuous exercise improvements. Our in vitro experiment demonstrated that the chemical inhibition of IP6K1 increased insulin signaling in C2C12 myotubes.
Conclusions
The in vivo and in vitro approaches used in the current study suggest that a decrease in muscle IP6K1 may be linked to whole body improvements in SI2*. In addition, high-intensity exercise reduces HPG in insulin-resistant individuals
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