2,288 research outputs found
A Community Capitals Approach To Assessing Immigrant Access To Community Resources Within A Meatpacking Community
This research uses a community capitals framework to explore immigrant access to community resources and the influence this access has on community solidarity. The community capitals framework allowed the researcher to target common community resources within Marshalltown, Iowa, a meatpacking community that has experienced a high influx of Latino immigrants. Successful integration of new immigrants is predicated on the availability of tools such as bilingual interpreters, bilingual outreach materials, and flexible identification systems. As institutional practices influence Latino access to public institutions, providing such tools becomes a key strategy for local governments on how to better serve their community by planning better service delivery adapted to its growing diversity
Letter from Frank K. Dunn to Mittie Horton Creekmore
Minister Frank K. Dunn writes from Jacksonville, Florida, on First Christian Church letterhead to express condolences to his cousin Mittie on the death of her husband and Hubert Creekmore\u27s father, Hiram Hubert Creekmore.https://egrove.olemiss.edu/creekmore/1071/thumbnail.jp
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.Abstract Background This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated with these clusters. Results Protein interaction graphs were separated into subgraphs of interconnected proteins, using the JUNG implementation of Girvan and Newman's Edge-Betweenness algorithm. Functions were sought for these subgraphs by detecting significant correlations with the distribution of Gene Ontology terms which had been used to annotate the proteins within each cluster. The method was implemented using freely available software (JUNG and the R statistical package). Protein clusters with significant correlations to functional annotations could be identified and included groups of proteins know to cooperate in cell metabolism. The method appears to be resilient against the presence of false positive interactions. Conclusion This method provides a useful tool for rapid screening of small to medium size protein interaction datasets.Published versio
Quantitative modeling of laser speckle imaging
We have analyzed the image formation and dynamic properties in laser speckle
imaging (LSI) both experimentally and with Monte-Carlo simulation. We show for
the case of a liquid inclusion that the spatial resolution and the signal
itself are both significantly affected by scattering from the turbid
environment. Multiple scattering leads to blurring of the dynamic inhomogeneity
as detected by LSI. The presence of a non-fluctuating component of scattered
light results in the significant increase in the measured image contrast and
complicates the estimation of the relaxation time. We present a refined
processing scheme that allows a correct estimation of the relaxation time from
LSI data.Comment: submitted to Optics Letter
Recent Decisions
Comments on recent decisions by Charles T. Dunn, Edward J. Flattery, Frank P. Salierno, Lawrence Turner, John M. Anderton, George S. Stratigos, John E. Cosgrove, Richard H. Keen, F. Gerard Feeney, and John C. Mowbray
Starvation-Associated Genome Restructuring Can Lead to Reproductive Isolation in Yeast
Knowledge of the mechanisms that lead to reproductive isolation is essential for understanding population structure and speciation. While several models have been advanced to explain post-mating reproductive isolation, experimental data supporting most are indirect. Laboratory investigations of this phenomenon are typically carried out under benign conditions, which result in low rates of genetic change unlikely to initiate reproductive isolation. Previously, we described an experimental system using the yeast Saccharomyces cerevisiae where starvation served as a proxy to any stress that decreases reproduction and/or survivorship. We showed that novel lineages with restructured genomes quickly emerged in starved populations, and that these survivors were more fit than their ancestors when re-starved. Here we show that certain yeast lineages that survive starvation have become reproductively isolated from their ancestor. We further demonstrate that reproductive isolation arises from genomic rearrangements, whose frequency in starving yeast is several orders of magnitude greater than an unstarved control. By contrast, the frequency of point mutations is less than 2-fold greater. In a particular case, we observe that a starved lineage becomes reproductively isolated as a direct result of the stress-related accumulation of a single chromosome. We recapitulate this result by demonstrating that introducing an extra copy of one or several chromosomes into naïve, i.e. unstarved, yeast significantly diminishes their fertility. This type of reproductive barrier, whether arising spontaneously or via genetic manipulation, can be removed by making a lineage euploid for the altered chromosomes. Our model provides direct genetic evidence that reproductive isolation can arise frequently in stressed populations via genome restructuring without the precondition of geographic isolation
Multiwavelength spectral evolution during the 2011 outburst of the very faint X-ray transient Swift J1357.2-0933
We report our multiwavelength study of the 2011 outburst evolution of the
newly discovered black hole candidate X-ray binary Swift J1357.2-0933. We
analysed the Swift X-ray telescope and Ultraviolet/Optical telescope (UVOT)
data taken during the ~7 months duration of the outburst. It displayed a 2-10
keV X-ray peak luminosity of ~1E35(D/1.5 kpc)^2 erg s-1 which classifies the
source as a very faint X-ray transient. We found that the X-ray spectrum at the
peak was consistent with the source being in the hard state, but it softened
with decreasing luminosity, a common behaviour of black holes at low
luminosities or returning to quiescence from the hard state. The correlations
between the simultaneous X-ray and ultraviolet/optical data suggest a system
with a black hole accreting from a viscous disc that is not irradiated. The
UVOT filters provide the opportunity to study these correlations up to
ultraviolet wavelengths a regime so far unexplored. If the black hole nature is
confirmed, Swift J1357.2-0933 would be one of the very few established black
hole very-faint X-ray transients.Comment: 6 pages, 2 tables, 5 figures. Accepted by MNRA
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