891 research outputs found
Low Reynolds number hydrodynamics of asymmetric, oscillating dumbbell pairs
Active dumbbell suspensions constitute one of the simplest model system for
collective swimming at low Reynolds number. Generalizing recent work, we derive
and analyze stroke-averaged equations of motion that capture the effective
hydrodynamic far-field interaction between two oscillating, asymmetric
dumbbells in three space dimensions. Time-averaged equations of motion, as
those presented in this paper, not only yield a considerable speed-up in
numerical simulations, they may also serve as a starting point when deriving
continuum equations for the macroscopic dynamics of multi-swimmer suspensions.
The specific model discussed here appears to be particularly useful in this
context, since it allows one to investigate how the collective macroscopic
behavior is affected by changes in the microscopic symmetry of individual
swimmers.Comment: 10 pages, to appear in EPJ Special Topic
Stationarity, soft ergodicity, and entropy in relativistic systems
Recent molecular dynamics simulations show that a dilute relativistic gas
equilibrates to a Juettner velocity distribution if ensemble velocities are
measured simultaneously in the observer frame. The analysis of relativistic
Brownian motion processes, on the other hand, implies that stationary
one-particle distributions can differ depending on the underlying
time-parameterizations. Using molecular dynamics simulations, we demonstrate
how this relativistic phenomenon can be understood within a deterministic model
system. We show that, depending on the time-parameterization, one can
distinguish different types of soft ergodicity on the level of the one-particle
distributions. Our analysis further reveals a close connection between time
parameters and entropy in special relativity. A combination of different
time-parameterizations can potentially be useful in simulations that combine
molecular dynamics algorithms with randomized particle creation, annihilation,
or decay processes.Comment: 4 page
Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases
A recent study described increased l‐lactate concentrations in ponies with gastrointestinal disease compared to horses, but blood glucose (BG) concentrations were not considered. The study tested the hypothesis that BG and l‐lactate concentrations are correlated in horses and ponies with gastrointestinal disease and that BG concentrations, not equid type (pony vs horse), are an independent predictor of L‐lactate concentrations. It was further hypothesized that equid type was an independent predictor of BG concentrations
Swimmer-tracer scattering at low Reynolds number
Understanding the stochastic dynamics of tracer particles in active fluids is
important for identifying the physical properties of flow generating objects
such as colloids, bacteria or algae. Here, we study both analytically and
numerically the scattering of a tracer particle in different types of
time-dependent, hydrodynamic flow fields. Specifically, we compare the tracer
motion induced by an externally driven colloid with the one generated by
various self-motile, multi-sphere swimmers. Our results suggest that force-free
swimmers generically induce loop-shaped tracer trajectories. The specific
topological structure of these loops is determined by the hydrodynamic
properties of the microswimmer. Quantitative estimates for typical experimental
conditions imply that the loops survive on average even if Brownian motion
effects are taken into account.Comment: 14 pages, to appear in Soft Matte
Atypical myopathy in the South-East of England: Clinicopathological data and outcome in hospitalised horses
Stochastic cycle selection in active flow networks
Active biological flow networks pervade nature and span a wide range of scales, from arterial blood vessels and bronchial mucus transport in humans to bacterial flow through porous media or plasmodial shuttle streaming in slime molds. Despite their ubiquity, little is known about the self-organization principles that govern flow statistics in such nonequilibrium networks. Here we connect concepts from lattice field theory, graph theory, and transition rate theory to understand how topology controls dynamics in a generic model for actively driven flow on a network. Our combined theoretical and numerical analysis identifies symmetry-based rules that make it possible to classify and predict the selection statistics of complex flow cycles from the network topology. The conceptual framework developed here is applicable to a broad class of biological and nonbiological far-from-equilibrium networks, including actively controlled information flows, and establishes a correspondence between active flow networks and generalized ice-type models. Keywords: networks; active transport; stochastic dynamics; topologyNational Science Foundation (U.S.) (Award CBET-1510768
Stochastic cycle selection in active flow networks.
Active biological flow networks pervade nature and span a wide range of scales, from arterial blood vessels and bronchial mucus transport in humans to bacterial flow through porous media or plasmodial shuttle streaming in slime molds. Despite their ubiquity, little is known about the self-organization principles that govern flow statistics in such nonequilibrium networks. Here we connect concepts from lattice field theory, graph theory, and transition rate theory to understand how topology controls dynamics in a generic model for actively driven flow on a network. Our combined theoretical and numerical analysis identifies symmetry-based rules that make it possible to classify and predict the selection statistics of complex flow cycles from the network topology. The conceptual framework developed here is applicable to a broad class of biological and nonbiological far-from-equilibrium networks, including actively controlled information flows, and establishes a correspondence between active flow networks and generalized ice-type models.This is the accepted manuscript. It is currently embargoed pending publication
mVOC: a database of microbial volatiles
Scents are well known to be emitted from flowers and animals. In nature, these volatiles are responsible for inter- and intra-organismic communication, e.g. attraction and defence. Consequently, they influence and improve the establishment of organisms and populations in ecological niches by acting as single compounds or in mixtures. Despite the known wealth of volatile organic compounds (VOCs) from species of the plant and animal kingdom, in the past, less attention has been focused on volatiles of microorganisms. Although fast and affordable sequencing methods facilitate the detection of microbial diseases, however, the analysis of signature or fingerprint volatiles will be faster and easier. Microbial VOCs (mVOCs) are presently used as marker to detect human diseases, food spoilage or moulds in houses. Furthermore, mVOCs exhibited antagonistic potential against pathogens in vitro, but their biological roles in the ecosystems remain to be investigated. Information on volatile emission from bacteria and fungi is presently scattered in the literature, and no public and up-to-date collection on mVOCs is available. To address this need, we have developed mVOC, a database available online at http://bioinformatics.charite.de/mvoc
Correlation between L-lactate and glucose concentrations and body condition score in healthy horses and ponies
Clinical features, anaesthetic management and perioperative complications seen in three horses with pheochromocytoma
Three horses presenting with colic signs to the Equine Referral Hospital at The Royal Veterinary College underwent general anaesthesia between September 2013 and November 2017 for emergency exploratory laparotomy. No obvious cause for the colic signs was identified in two horses, while a haemoperitoneum was identified in the third. All horses were euthanased within 12 hours of surgery due to deteriorating haemodynamic instability and/or intractable pain. Postmortem examination revealed an adrenal mass in each case, confirmed to be a pheochromocytoma on histopathology. In retrospect, each horse had some hallmark characteristics consistent with a functional pheochromocytoma, including hyperglycaemia and hyperlactataemia. Extremely high packed cell volume (PCV) (>65 per cent) was also identified in two horses, with a high-normal PCV found in the haemoperitoneum case. Perioperative haemodynamic instability was predominantly characterised by episodes of intermittent hypertension and tachycardia
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