888 research outputs found
Creating a clinician. A methodology to evaluate clinical reasoning and case-based decision making.
Emerging technologies for sustainable irrigation: Selected papers from the 2015 ASABE and IA irrigation symposium
Citation: Lamm, F. R., Stone, K. C., Dukes, M. D., Howell, T. A., Sr., Robbins, J. W. D., Jr., & Mecham, B. Q. (2016). Emerging technologies for sustainable irrigation: Selected papers from the 2015 ASABE and IA irrigation symposium. Transactions of the Asabe, 59(1), 155-161. doi:10.13031/trans.59.11706This article is an introduction to the "Emerging Technologies in Sustainable Irrigation: A Tribute to the Career of Terry Howell, Sr." Special Collection in this issue of Transactions of the ASABE and the next issue of Applied Engineering in Agriculture, consisting of 16 articles selected from 62 papers and presentations at the joint irrigation symposium of ASABE and the Irrigation Association (IA), which was held in November 2015 in Long Beach, California. The joint cooperation on irrigation symposia between ASABE and IA can be traced back to 1970, and this time period roughly coincides with the career of Dr. Howell. The cooperative symposia have offered an important venue for discussion of emerging technologies that can lead to sustainable irrigation. This most recent symposium is another point on the continuum. The articles in this Special Collection address three major topic areas: evapotranspiration measurement and determination, irrigation systems and their associated technologies, and irrigation scheduling and water management. While these 16 articles are not inclusive of all the important advances in irrigation since 1970, they illustrate that continued progress occurs by combining a recognition of the current status with the postulation of new ideas to advance our understanding of irrigation engineering and science. The global food and water challenges will require continued progress from our portion of the scientific community. This article serves to introduce and provide a brief summary of the Special Collection. © 2016 American Society of Agricultural and Biological Engineers
Comparison of tumour-based (Petersen Index) and inflammation-based (Glasgow Prognostic Score) scoring systems in patients undergoing curative resection for colon cancer
After resection, it is important to identify colon cancer patients, who are at a high risk of recurrence and who may benefit from adjuvant treatment. The Petersen Index (PI), a prognostic model based on pathological criteria is validated in Dukes' B and C disease. Similarly, the modified Glasgow Prognostic Score (mGPS) based on biochemical criteria has also been validated. This study compares both the scores in patients undergoing curative resection of colon cancer. A total of 244 patients underwent elective resection between 1997 and 2005. The PI was constructed from pathological reports; the mGPS was measured pre-operatively. The median follow-up was 67 months (minimum 36 months) during which 109 patients died; 68 of them from cancer. On multivariate analysis of age, Dukes' stage, PI and mGPS, age (hazard ratio, HR, 1.74, P=0.001), Dukes' stage (HR, 3.63, P<0.001), PI (HR, 2.05, P=0.010) and mGPS (HR, 2.34, P<0.001) were associated independently with cancer-specific survival. Three-year cancer-specific survival rates for Dukes' B patients with the low-risk PI were 98, 92 and 82% for the mGPS of 0, 1 and 2, respectively (P<0.05). The high-risk PI population is small, in particular for Dukes' B disease (9%). The mGPS further stratifies those patients classified as low risk by the PI. Combining both the scoring systems could identify patients who have undergone curative surgery but are at high-risk of cancer-related death, therefore guiding management and trial stratification
Random tree growth by vertex splitting
We study a model of growing planar tree graphs where in each time step we
separate the tree into two components by splitting a vertex and then connect
the two pieces by inserting a new link between the daughter vertices. This
model generalises the preferential attachment model and Ford's -model
for phylogenetic trees. We develop a mean field theory for the vertex degree
distribution, prove that the mean field theory is exact in some special cases
and check that it agrees with numerical simulations in general. We calculate
various correlation functions and show that the intrinsic Hausdorff dimension
can vary from one to infinity, depending on the parameters of the model.Comment: 47 page
Epigenetic Response to Habitat Change: Changes Variation in DNA Methylation Frequencies and Generational Transmission Vary with Invasion Status
Epigenetic mechanisms may be important for a native species’ response to rapid environmental change. Red Imported Fire Ants (Solenopsis invicta Santschi, 1916) were recently introduced to areas occupied by the Eastern Fence Lizard (Sceloporus undulatus Bosc & Daudin, 1801). Behavioral, morphological and physiological phenotypes of the Eastern Fence Lizard have changed following invasion, creating a natural biological system to investigate environmentally induced epigenetic changes. We tested for variation in DNA methylation patterns in Eastern Fence Lizard populations associated with different histories of invasion by Red Imported Fire Ants. At methylation sensitive amplified fragment length polymorphism loci, we detected a higher diversity of methylation in Eastern Fence Lizard populations from Fire Ant uninvaded versus invaded sites, and uninvaded sites had higher methylation. Our results suggest that invasive species may alter methylation frequencies and the pattern of methylation among native individuals. While our data indicate a high level of intrinsic variability in DNA methylation, DNA methylation at some genomic loci may underlie observed phenotypic changes in Eastern Fence Lizard populations in response to invasion of Red Imported Fire Ants. This process may be important in facilitating adaptation of native species to novel pressures imposed by a rapidly changing environment
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