871 research outputs found
Voting & The Chair
Voting is the primary mechanism which this organizations utilizes to represent the student body
Representation & Academic Advocacy Bill
Beginning with the 2017-2018 school year, the Academic Affairs Council is dissolved, as is the chair and thus the position on Senate
PDB19 ESTIMATING THE COST EFFECTIVENESS IN THE UK OF VILDAGLIPTIN COMPARED TO PIOGLITAZONE AS ADD-ON THERAPY TO METFORMIN USING THE SHEFFIELD TYPE 2 DIABETES MODEL
Control of Phragmites communis using low rate glyphosate applications and TopFilm adjuvant
An experiment to test the hypothesis that the addition of TopFilm adjuvant would reduce the effective concentration of glyphosate required to control Phragmites communis, the common reed
Optimal design of isolated mini-grids with deterministic methods: matching predictive operating strategies with low computational requirements
The lack of electricity access is increasingly concentrated in rural areas of developing countries, in which mini-grids are often a suitable solution; however, given the high risks, it is crucial to minimize costs. This paper aims at analyzing existing methodologies for the optimal design of mini-grids combined with different operating strategies. Typical system operations, like the load-following (LFS) and cycle charging (CCS) strategies, are compared with the more demanding predictive strategies based on Mixed-Integer Linear Programming (MILP). The problem is formulated and solved with Particle Swarm Optimization (PSO), so to simulate traditional and predictive operating strategies. Two reformulations based on the proposed Search Space Update are also detailed and compared with the so-called one-shot MILP model, which is able to con-jointly optimize both the design and the operation of the system, in order to reduce computational requirements with the predictive strategy. The results, tailored with data from a rural mini-grid in Kenya, highlight that heuristic methodologies can perform better than the traditional MILP approach, both in terms of optimality and computational time, especially when advanced operating strategies are considered. Conventional operating strategies (LFS or CCS) appear to be sub-optimal, but require very little computational requirements, which makes them suitable for preliminary designs
A review of public health economic modelling in the National Institute for Health and Care Excellence (NICE)
Background: The National Institute for Health and Care Excellence (NICE) use economic modelling to inform judgements whenever further insight is required for decision-making. Doing so for public health guidance poses several challenges. The study’s objective was to investigate the level of heterogeneity in NICE’s public health economic models with regards to economic evaluation techniques, perspectives on outcomes and the measurement of non-health benefits.
Methods: A review of all economic modelling reports published by NICE’s Centre for Public Health (CPH) as part of their guidance.
Results: The review identified 56 eligible pieces of public health over the relevant period. Of these, 43 used economic modelling and 13 used no formal economic model. In total 61 economic models were used. Though the CPH specifies a reference case, in practice there is a large amount of variability from one model to the next. The most common perspective used for evaluations was that of the National Health Service (NHS); the most common economic evaluation approach was cost-utility analysis (CUA). 23 of the 56 topics used other combinations of perspective and technique, which allowed them to incorporate non-health effects, such as productivity, the effect on taxes raised and benefits spending, costs to the criminal justice sector, the effect on educational attainment and general wellbeing.
Conclusions: NICE regularly updates its reference case, and non-CUA evaluation techniques have become more prominent in recent years. The results highlight the genuine advantages of having a variety of economic evaluation techniques available, which can be matched with the given topic. While it is always necessary to be wary of the possibility of gamesmanship and cherry picking, there is a surprising alignment between many approaches in certain circumstances
APPLICATION OF BIOMECHANICS TO THE PREVENTION OF OVERLOAD INJURIES IN ELITE SOCCER PLAYERS.
Structural alterations of the foot and inadequate design of sports footwear, as well as overtraining, have been determined to be risk factors for overload injuries during sports practice. A biomechanical analysis protocol was designed to study both, the foot and sports footwear statically and dynamically. This protocol was applied on 47 soccer players of the Spanish Premier League. Amongst the results we should point out that 53.3% of the players had cavus feet. 14.8% of the players deformed the boots. 44.7% of the players studied registered high pressures over the metatarsal heads. and 19.1 % registered high ones at the first toe. 44.7% of the players showed an excessive supination pattern. The data obtained gave us information about the static and dynamic patterns of the elite soccer player. With the individual information the assessment of suitable footwear was carried out for each player. The correct application of this protocol could be used in the diagnosis or prevention of overtraining and in the detection of foot and gait pathologies
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