Developing a real-time monitoring traceability system for cold chain of Tricholoma matsutake

Tricholoma matsutake (T. matsutake) is a special type of fungus known as "the king of bacteria", and has the very high economic value. However, it is also very difficult to transport due to its corruptibility. Therefore, tracing and tracking the quality and safety of T. matsutake in the cold chain is very important and necessary. Based on changes in the cold chain environmental parameters determine the safety of T. matsutake is a viable option. This paper developed and tested a real-time monitoring traceability system (RM-TM) using emerging Internet of Things (IoT) technologies for monitoring the cold chain logistics environmental parameters of T. matsutake. Finally, system testing and evaluation have shown that RM-TM can track and monitor temperature, humidity, oxygen and carbon dioxide fluctuations in the cold chain in real-time. In addition, the collected data can be used to increase the transparency of cold chain logistics and to more effectively control quality, safety, and traceability. In general, the system evaluation results show that it is reliable and meets the requirements of users

Cost-effectiveness of Chemotherapeutic Colon Cancer Regimens

https://openworks.mdanderson.org/sumexp21/1129/thumbnail.jp

SUATU KAJIAN TENTANG PENGGUNAAN PUTUSAN KASASI RNSEBAGAI ALAT BUKTI DALAM PENINJAUAN KEMBALI

ABSTRAKRIA MANDA SARI: SUATU KAJIAN TENTANG PENGGUNAAN2014PUTUSAN KASASI SEBAGAI ALAT BUKTI DALAM PENINJAUAN KEMBALIFakultas Hukum Universitas Syiah Kuala(vii, 55) pp., bibL.NURSITI, S.H., M.Hum.Pasal 263 ayat (2) huruf a KUHAP menyebutkan salah satu alasan diajukan peninjauan kembali adalah apabila terdapat keadaan baru yang menimbulkan dugaan kuat bahwa jika keadaan itu sudah diketahui pada sidang masih berlangsung, maka hasilnya akan menjadi putusan yang berbeda. Di dalam praktek timbul suatu masalah dimana terdakwa melakukan Peninjauan Kembali karena adanya kekeliruan yang nyata dalam hal kesalahan penerapan hukum oleh majelis hakim kasasi dalam hal menjatuhkan pemidanaan terhadap terdakwa dan alasan terdakwa melakukan peninjauan kembali yaitu karena adanya bukti baru (novum).Tujuan skripsi ini untuk mendapatkan kejelasan tentang penggunaan Putusan Kasasi sebagai alat bukti untuk Peninjauan Kembali dan untuk menjelaskan upaya hukum yang dapat dilakukan jika terdapat kekeliruan dalam Putusan Peninjauan Kembali.Data dalam skripsi ini diperoleh melalui penelitian kepustakaan dan penelitian lapangan. Penelitian kepustakaan dilakukan untuk memperoleh data sekunder dengan cara mempelajari buku-buku mengenai Peninjauan Kembali, peraturan perundang-undangan yang berhubungan dengan masalah yang diteliti. Penelitian lapangan dilakukan guna memperoleh data primer melalui wawancara dengan responden dan informan.Berdasarkan hasil penelitian diketahui bahwa Putusan Kasasi dapat dijadikan alat bukti, jika pada putusan tersebut dapat dinilai adanya pertentangan, kekeliruan, atau kekhilafan dari hakim, sehingga alat bukti baru berupa putusan pengadilan atau putusan Mahkamah Agung tersebut bisa dipertimbangkan sebagai alat bukti, asal relevan dan saling berhubungan.Jika Peninjauan Kembali terdapat kekeliruan maka tidak ada upaya hukum lain. Didasarkan pada KUHAP maka Peninjauan Kembali hanya dapat diajukan satu kali saja, namun dengan adanya Putusan Mahkamah Konstitusi No 34/PUU-XI/2013 maka Peninjauan Kembali dapat diajukan lebih dari satu kali.Hakim harus benar-benar cermat dalam memutuskan suatu perkara jangan hanya melihat kebiasaan-kebiasaan yang bersifat formal pada persidangan, namun hakim juga harus menggunakan putusan-putusan sebelumnya sebagai yurisprudensi. Disarankan kepada DPRRI agar dapat segera menyusun kebijakan untuk mengatur tatacara Peninjauan Kembali yang dapat diajukan lebih dari satu kali agar keadilan dapat tercapai tanpa mengenyampingkan kepastian hukum sesuai dengan Putusan Mahkamah Konstitusi No 34/PUU-XI/2013Banda Ace

Real-World Patterns of Everolimus Use in Patients with Metastatic Breast Cancer

© AlphaMed Press 2020 Background: There is limited literature on patterns of everolimus use and subsequent hospitalizations and emergency room (ER) visits in real-world clinical practice. In this study, we describe patterns of everolimus use and hospitalizations and ER visits in a large cohort of patients with breast cancer (BC). Materials and Methods: Patients with BC treated with everolimus were identified in the MarketScan database from 2009 to 2016. The pattern of everolimus use and frequency of associated ER visits and hospitalizations during treatment (between the first claim and 30 days after the last claim for everolimus) were identified. Descriptive statistics and regression models were used. Results: A total of 3,556 everolimus users were identified (median age of 60 years; median days of use, 112). The initial prescribed dose was 10 mg in 74.8% of the patients. Compared with the initial dose, 23.5% of patients had a dose change. Forty-six percent of patients were hospitalized or had an ER visit during the treatment with everolimus. Age greater than 71, higher comorbidity score, treatment year prior to 2012, and lower initial dose were found to be significantly associated with ER visit/hospitalization in the regression models. Conclusions: A significant proportion of patients receiving everolimus had an ER visit or hospitalization during the use of everolimus. These results provide data regarding risks and benefits of treatment with everolimus. These results will be helpful in identifying patients at higher risk of hospitalizations or ER visits and facilitate evidence-based decision making to avoid serious complications. Implications for Practice: Everolimus, a mammalian target of rapamycin inhibitor, is approved in combination with exemestane in patients with hormone receptor–positive tumors previously treated with anastrozole or letrozole. As new drugs become available, it is crucial to understand the adverse events and potential complications associated with the use of such drugs in the general population, outside of the controlled clinical trial setting. This study describes the patterns of everolimus use and adverse events, including hospitalization and emergency room visits, in a large cohort of patients with metastatic breast cancer in routine practice

Determination of the downwelling diffuse attenuation coefficient of lakewater with the sentinel-3A OLCI

The Ocean and Land Color Imager (OLCI) on the Sentinel-3A satellite, which was launched by the European Space Agency in 2016, is a new-generation water color sensor with a spatial resolution of 300 m and 21 bands in the range of 400-1020 nm. The OLCI is important to the expansion of remote sensing monitoring of inland waters using water color satellite data. In this study, we developed a dual band ratio algorithm for the downwelling diffuse attenuation coefficient at 490 nm (Kd(490)) for the waters of Lake Taihu, a large shallow lake in China, based on data measured during seven surveys conducted between 2008 and 2017 in combination with Sentinel-3A-OLCI data. The results show that: (1) Compared to the available Kd(490) estimation algorithms, the dual band ratio (681 nm/560 nm and 754 nm/560 nm) algorithm developed in this study had a higher estimation accuracy (N = 26, coefficient of determination (R2) = 0.81, root-mean-square error (RMSE) = 0.99m-1and mean absolute percentage error (MAPE) = 19.55%) and validation accuracy (N = 14, R2= 0.83, RMSE = 1.06 m-1and MAPE = 27.30%), making it more suitable for turbid inland waters; (2) A comparison of the OLCI Kd(490) product and a similar Moderate Resolution Imaging Spectroradiometer (MODIS) product reveals a high consistency between the OLCI and MODIS products in terms of the spatial distribution of Kd(490). However, the OLCI product has a smoother spatial distribution and finer textural characteristics than the MODIS product and contains notably higher-quality data; (3) The Kd(490) values for Lake Taihu exhibit notable spatial and temporal variations. Kd(490) is higher in seasons with relatively high wind speeds and in open waters that are prone to wind- and wave-induced sediment resuspension. Finally, the Sentinel-3A-OLCI has a higher spatial resolution and is equipped with a relatively wide dynamic range of spectral bands suitable for inland waters. The Sentinel-3B satellite will be launched soon and, together with the Sentinel-3A satellite, will form a two-satellite network with the ability to make observations twice every three days. This satellite network will have a wider range of application and play an important role in the monitoring of inland waters with complex optical properties

Inversion of inherent optical properties in optically complex waters using sentinel-3A/OLCI images: A case study using China\u27s three largest freshwater lakes

Inherent optical properties (IOPs) play an important role in underwater light field, and are difficult to estimate accurately using satellite data in optically complex waters. To study water quality in appropriate temporal and spatial scales, it is necessary to develop methods to obtain IOPs form space-based observation with quantified uncertainties. Field-measured IOP data (N = 405) were collected from 17 surveys between 2011 and 2017 in the three major largest freshwater lakes of China (Lake Chaohu, Lake Taihu, and Lake Hongze) in the lower reaches of the Yangtze River and Huai River (LYHR). Here we provide a case-study on how to use in-situ observation of IOPs to devise an improved algorithm for retrieval of IOPs. We then apply this algorithm to observation with Sentinel-3A OLCI (Ocean and Land Colour Instrument, corrected with our improved AC scheme), and use in-situ data to show that the algorithm performs better than the standard OLCI IOP product. We use the satellite derived products to study the spatial and seasonal distributions of IOPs and concentrations of optically active constituents in these three lakes, including chlorophyll-a (Chla) and suspended particulate matter (SPM), using all cloud-free OLCI images (115 scenes) over the lakes in the LYHR basin in 2017. Our study provides a strategy for using local and remote observations to obtain important water quality parameters necessary to manage resources such as reservoirs, lakes and coastal waters

Atomic oxygen adsorption and incipient oxidation of the Pb(111) surface: A density-functional theory study

We study the atomic oxygen adsorption on Pb(111) surface by using density-functional theory within the generalized gradient approximation and a supercell approach. The atomic and energetic properties of purely on-surface and subsurface oxygen structures at the Pb(111) surface are systematically investigated for a wide range of coverages and adsorption sites. The fcc and tetra-II sites (see the text for definition) are found to be energetically preferred for the on-surface and subsurface adsorption, respectively, in the whole range of coverage considered. The on-surface and subsurface oxygen binding energies monotonically increase with the coverage, and the latter is always higher than the former, thus indicating the tendency to the formation of oxygen islands (clusters) and the higher stability of subsurface adsorption. The on-surface and subsurface diffusion-path energetics of atomic oxygen, and the activation barriers for the O penetration from the on-surface to the subsurface sites are presented at low and high coverages. In particular, it is shown that the penetration barrier from the on-surface hcp to the subsurface tetra-I site is as small as 65 meV at low coverage ($\Theta$=0.25). The other properties of the O/Pb(111) system, including the charge distribution, the lattice relaxation, the work function, and the electronic density of states, are also studied and discussed in detail, which consistently show the gradually stabilizing ionic O-Pb bond with increase of the oxygen coverage.Comment: 31 pages, 16 figure

Optimized layout of supporting facilities in mountainous industrial parks: a case study of Chongqing Dadi Industrial Park

Industrial parks play a pivotal role in driving urban economic growth in China, particularly in light of the country's extensive mountainous terrain. Effective arrangement of supporting facilities within these parks is crucial for steering industries towards high-quality development. However, the intricate topography of mountainous regions presents challenges in devising optimal layouts for these facilities. This article adopts a user-centric perspective to investigate the impact of mountainous terrain on user fatigue within industrial parks. We employ equivalent coefficient methods to establish a correlation between undulating paths in mountainous terrain and flat paths. This correlation serves as the foundation for a visual analytical tool designed to facilitate the rational placement of supporting facilities in mountainous industrial parks. To validate our approach, we conduct an empirical analysis of the supporting facility layout at Chongqing Dadi Industrial Park. The insights gleaned from our study provide a basis for optimizing the placement of supporting facilities in mountainous industrial parks, enhancing user experiences and aligning with urban growth trajectories. In conclusion, our research offers dual benefits: firstly, it provides a scientific framework for guiding the rational layout of supporting facilities in mountainous industrial parks, addressing the challenges posed by complex terrain. Secondly, it offers practical insights into the comprehensive planning and design of these parks, promoting sustainable urban and economic growth. Our research thus emerges as a valuable resource for the advancement and optimization of mountainous industrial parks in China

Quantum blockade and loop current induced by a single lattice defect in graphene nanoribbons

We investigate theoretically the electronic transport properties in narrow graphene ribbons with an adatom-induced defect. It is found that the lowest conductance step of a metallic graphene nanoribbon may develop a dip even down to zero at certain values of the Fermi energy due to the defect. Accompanying the occurrence of the conductance dip, a loop current develops around the defect. We show how the properties of the conductance dip depend on the parameters of the defect, such as the relative position and severity of the defect as well as the width and edges of the graphene ribbons. In particular, for metallic armchair-edges graphene nanoribbons, whether the conductance dip appears or not, they can be controlled by choosing the position of the single defect.Comment: 6 pages, 6 figure