The renormalization of the effective Lagrangian with spontaneous symmetry breaking: the SU(2) case

We study the renormalization of the nonlinear effective SU(2) Lagrangian up to $O(p^4)$ with spontaneous symmetry breaking. The Stueckelberg transformation, the background field gauge, the Schwinger proper time and heat kernel method, and the covariant short distance expansion technology, guarantee the gauge covariance and incooperate the Ward indentities in our calculations. The renormalization group equations of the effective couplings are derived and analyzed. We find that the difference between the results gotten from the direct method and the renormalization group equation method can be quite large when the Higgs scalar is far below its decoupling limit.Comment: ReVTeX, 12 figures, 22 pages, some bugs are kicked off from programs, numerical analysis is renew

Practical tips to using formalin-fixed paraffin-embedded tissue archives for molecular diagnostics in a South African setting

BACKGROUND : Formalin-fixed paraffin-embedded (FFPE) tissue archives in hospitals, biobanks, and others offer a vast collection of extensive, readily available specimens for molecular testing. Unfortunately, the use of tissue samples for molecular diagnostic applications is challenging; thus, the forensic pathology FFPE tissue archives in Africa have been a largely unexploited genetic resource, with the usability of DNA obtainable from these samples being unknown. INTERVENTION : The study, conducted from January 2015 to August 2016, determined the usefulness of FFPE tissue as a reliable source of genetic material for successful post-mortem molecular applications and diagnostics. Formalin-fixed paraffin-embedded tissue samples were collected and archived from autopsies conducted over 13 years in the forensic medicine department of the University of Pretoria (Pretoria, South Africa). Deoxyribonucleic acid from FFPE tissue samples and control blood samples was amplified by high-resolution melt realtime polymerase chain reaction before sequencing. The procurement parameters and fixation times were compared with the quantity and quality of the extracted DNA and the efficiency of its subsequent molecular applications. LESSONS LEARNT : This study has shown that FFPE samples are still usable in molecular forensics, despite inadequate sample preparation, and offer immense value to forensic molecular diagnostics. RECOMMENDATIONS : FFPE samples fixed in formalin for more than 24 h should still be used in molecular diagnostics or research, as long as the primer design targets amplicons not exceeding 300 base pairs.The Genomics Research Institute (University of Pretoria) and the South African National Research Foundation.http://www.ajlmonline.orgam2023Chemical PathologyForensic Medicin

Cardiovascular deaths : what do the genes say?

Cardiovascular diseases (CVDs) are ever-increasing, and as such are considered to be one of the most concerning public health burdens worldwide. They remain the leading cause of death across the world (~17.7 million deaths were reported in 2015), accounting for 31% of all global deaths.http://www.samj.org.zaam2023Chemical PathologyForensic Medicin

Light scattering observations of spin reversal excitations in the fractional quantum Hall regime

Resonant inelastic light scattering experiments access the low lying excitations of electron liquids in the fractional quantum Hall regime in the range $2/5 \geq \nu \geq 1/3$. Modes associated with changes in the charge and spin degrees of freedom are measured. Spectra of spin reversed excitations at filling factor $\nu \gtrsim 1/3$ and at $\nu \lesssim 2/5$ identify a structure of lowest spin-split Landau levels of composite fermions that is similar to that of electrons. Observations of spin wave excitations enable determinations of energies required to reverse spin. The spin reversal energies obtained from the spectra illustrate the significant residual interactions of composite fermions. At $\nu = 1/3$ energies of spin reversal modes are larger but relatively close to spin conserving excitations that are linked to activated transport. Predictions of composite fermion theory are in good quantitative agreement with experimental results.Comment: Submitted to special issue of Solid State Com

Superselectors: Efficient Constructions and Applications

We introduce a new combinatorial structure: the superselector. We show that superselectors subsume several important combinatorial structures used in the past few years to solve problems in group testing, compressed sensing, multi-channel conflict resolution and data security. We prove close upper and lower bounds on the size of superselectors and we provide efficient algorithms for their constructions. Albeit our bounds are very general, when they are instantiated on the combinatorial structures that are particular cases of superselectors (e.g., (p,k,n)-selectors, (d,\ell)-list-disjunct matrices, MUT_k(r)-families, FUT(k, a)-families, etc.) they match the best known bounds in terms of size of the structures (the relevant parameter in the applications). For appropriate values of parameters, our results also provide the first efficient deterministic algorithms for the construction of such structures

Brane fluctuation and the electroweak chiral Lagrangian

We use the external field method to study the electroweak chiral Lagrangian of the extra dimension model with brane fluctuation. Under the assumption that the contact terms between the matters of the standard model and KK excitations are heavily suppressed, we use the standard procedure to integrate out the quantum fields of KK excitations and the equation of motion to eliminate the classic fields of KK excitations. At one-loop level, we find that up to the order $O(p^4)$, due to the momentum conservation of the fifth dimension and the gauge symmetry of the zero modes, there is no constraint on the size of extra dimension. This result is consistent with the decoupling theorem. However, meaningful constraints can come from those operators in $O(p^6)$, which can contribute considerably to some anomalous vector couplings and can be accessible in the LC and LHC.Comment: Revised version, 20 pages in ReVTeX, to appear in PR

The added value of molecular-based diagnostics in the African forensic medical setting

Sudden unexpected infant death (SUDI) is reported to be an extraordinarily high burden in sub-Saharan Africa, with the incidence rate in South Africa among the highest in the world. It is common for the cause of many such infant deaths to remain unexplained even after a full medico-legal death investigation, and then to be categorised as a sudden unexplained infant death (SUID). Fortunately, advances in molecular- based diagnostics allow researchers to identify numerous underlying inherited cardiac arrhythmogenic disorders in many SUDI cases, with a predominance of variants identified in the SCN5A gene. Such cardiac arrhythmogenic-related sudden deaths generally present with no structural alterations of the heart that are macroscopically identifiable at autopsy, therefore highlighting the importance of post mortem genetic testing. We report on a significant genetic finding that was made on a SUDI case in which the cause was ascribed to an acute bacterial pneumonia but it was still subjected to post mortem genetic testing of the SCN5A gene. The literature shows that many SUDI cases diagnosed with inherited cardiac arrhythmogenic disorders have demonstrated a viral prodrome within days of their death. It is therefore not uncommon for these cardiac disorders in infants to be mistaken for flu, viral upper respiratory tract infection or pneumonia, and without the incorporation of post mortem genetic testing, any other contributory causes of these deaths are often disregarded. This study highlights the need for research reporting on the genetics of inherited cardiac disorders in Africa.The Genomic Research Institute from the University of Pretoria, South Africa.http://www.cvja.co.zaam2023Forensic Medicin

The trade-off between tidal-turbine array yield and impact on flow: A multi-objective optimisation problem

Abstract This paper introduces a new approach for investigating trade-offs between different societal objectives in the design of tidal-turbine arrays. This method is demonstrated through the trade-off between the yield of an array, and the extent to which that array alters the flow. This is posed as a multi-objective optimisation problem, and the problem is investigated using the array layout optimisation tool OpenTidalFarm. Motivated by environmental concerns, OpenTidalFarm is adapted to not only maximise array yield but also to minimise the effect of the array upon the hydrodynamics of the region, specifically the flow velocity. A linear scalarisation of the multi-objective optimisation problem is solved for a series of different weightings of the two conflicting objectives. Two idealised test scenarios are evaluated and in each case a set of Pareto solutions is found. These arrays are assessed for the power they generate and the severity of change they cause in the flow velocity. These analyses allow for the identification of trade-offs between these two objectives, while the methods proposed can similarly be applied to the two key societal objectives of energy production and conservation, thus providing information that could be valuable to stakeholders and policymakers when making decisions on array design

Ensiling quality of maize as influenced by the addition of wet distillers grains with soluble

Wet distillers grains with soluble (WDGS) were blended with whole maize plants on an as-fed basis at 0%, 20%, 30%, and 40% and ensiled in 3 L bottles to evaluate the silage fermentation characteristics and ensiling quality in a complete randomized design. Each treatment was ensiled in 15 mini-silos and three bottles were opened on days 7, 21, 42 and 120. Each treatment was sampled for chemical composition and silage fermentation parameters. There was a steady decrease in dry matter (DM) concentration of silage with increasing WDGS inclusion level over time. Initial pH (at day 0) decreased with increasing level of WDGS inclusion, with 40% WDGS inclusion recording the lowest pH (3.6) at day 120. Lactic acid concentration was slightly lower for WDGS-blended silages compared with the control. In contrast, the acetic acid concentration for WDGS-blended silage increased across all treatments, suggesting a possible diminished effect of clostridium bacteria in the silage owing to a reduced pH. The acid detergent fibre (ADF), neutral detergent fibre (NDF) and IVDOM (in vitro digestible organic matter) did not differ at the time of ensiling among treatments. During post ensiling, ADF increased slightly over time for WDGS-blended treatments (at 120 days). The results from this study indicated that WDGS could be ensiled effectively with maize plants without compromising silage quality.WAVNhttp://www.sasas.co.zaam2016Animal and Wildlife Science

BESII Detector Simulation

A Monte Carlo program based on Geant3 has been developed for BESII detector simulation. The organization of the program is outlined, and the digitization procedure for simulating the response of various sub-detectors is described. Comparisons with data show that the performance of the program is generally satisfactory.Comment: 17 pages, 14 figures, uses elsart.cls, to be submitted to NIM