Modeling of matrix of correspondences of transactivator on example of the Yekaterinburg municipal unitary enterprise "Tram and trolleybus management"

Настоящая статья посвящена исследованию пассажиропотока транспортной сети городского электротранспорта г. Екатеринбурга на примере ЕМУП «Трамвайно-троллейбусное управление». Разработано программное приложение для анализа транзакциопотока трамвайно-троллейбусной сети в виде матрицы корреспонденций. Приложение c помощью SQL запросов формирует отчет в виде таблицы, результаты которой позволяют построить графы перемещения пассажиров между административными районами и внутри их. Графическое представление результатов анализа транзакциопотока визуализирует аналитическую обработку статистических данных об использовании городского электротранспорта в различных районах г. Екатеринбурга.This article is dedicated to research of urban passenger of a transport network electric transport Yekaterinburg on the example of municipal unitary enterprise "Tram and trolleybus management". Programmatic application is worked out for the analysis of transactivator of tram-car-trolleybus network as a matrix of correspondences. Appendix a report forms the c help of SQL of queries as a table the results of that allow to build the columns of moving of passengers between administrative districts and into them. Graphic presentation of results of analysis of transactivator visualizes the analytical processing of statistical data about the use of municipal electric transport in different districts Yekaterinburg

Model of fuzzy controller of autoinformer

The article presents a model of a fuzzy control system of autoinformer of public transport. The purpose of the development is providing flexible adjustment of the start time of pronunciation of tram’s stop name and improving the quality of service for public transport passengers. A model of fuzzy controller for generating a control signal for starting of pronunciation is developed. Presented the linguistic variables, terms and examples of fuzzy logical rules. For comparison purposes, a model of a simple classic program controller is presented. Numerical experiments show the advantages of fuzzy controller.Представлена модель системы управления автоинформатора общественного транспорта с нечетким регулятором. Цель разработки: обеспечение гибкой настройки системы управления временем начала озвучивания остановки и повышение качества обслуживания пассажиров общественного транспорта. Предложена модель нечеткого регулятора для формирования управляющего сигнала начала объявления остановки. Представлены лингвистические переменные, термы и примеры правил нечеткого логического вывода для работы нечеткого регулятора. В целях сравнения и тестирования предложена модель простого четкого регулятора с использованием программного управления. Проведены численные эксперименты, которые показывают преимущества нечеткого регулятора перед четким регулятором

Development of an Intellectual Educational and Diagnostic Complex for the Histological Analysis of Thyroid Tumors

The purpose of this project is the creation of an interactive intellectual training system based on the DBMS, which allows to organize and store information, transfer and copy data for employees. The already existing images and their characteristics are structured, a decision support system is developed for the recognition of tumors and suspicious cells, which saves time for an already experienced oncologist. This system allows to increase the accuracy of diagnosis. Educational and diagnostic complexes help to accumulate experience for young specialists in the field of image analysis, carry out comparative research, which speeds up the learning process, promotes professional development of the specialist. Keywords: diagnostic,thyroid, oncological, aspiration biopsy

Intellectual Information and Training System for Software and Hardware Complexes of Morphological Diagnostics of Esophageal Tumors

The aim of the work is to create a system of formalizing knowledge in the histological diagnosis of esophageal tumors and systematic transfer of knowledge to less experienced specialists. It is also a system that will provide support in making a decision in a histological diagnosis. Keywords: esophagus, morphological, automatic work place, system of support for the solutio

Safety of Antibacterial and Antiprotozoal Medicinal Products

The experts of the Scientific Centre for Expert Evaluation of Medicinal Products analysed administrative decisions of foreign regulatory authorities on the recalls of antibacterial and antiprotozoal medicinal products and/or the need for labelling updates due to changes in the safety profile. The analysis revealed 16 decisions containing information on the following medicines registered in Russia: ertapenem, сeftriaxone, cefazolin, аmoxicillin, сefoperazone+sulbactam, piperacillin+tazobactam, сlindamycin, teicoplanin, rifampin, co-trimoxazole, hydroxychloroquine

Качество жизни при цервикальной дистонии

The aim of the study was to study the physical and psychological components regarding the quality of life of patients with cervical dystonia.Material and methods. 170 respondents were examined. The main group included 120 patients with cervical dystonia, 50 patients were included in the control group, consisting of patients with cervicalgia of various genesis. The diagnosis of cervical dystonia met uniform criteria for the diagnosis and treatment of dystonia adopted in 2011 by the European Federation of Neurological Societies and the Movement Disorders Society (European Federation of Neurological Societies / Movement Disorders Society, EFNS / MDS). In the control group, the pain syndrome of the cervical spine was caused by a degenerative process and was confirmed by X-ray examination and /or MRI. As part of our research, we determined the quality of life in men and women in both groups using the SF-36 questionnaire with a study of the parameters of physical and psychological well-being.Results and conclusion. A considerably significant effect of cervical dystonia on the somatic and mental  parameters regarding the quality of life in both men and women has been established. Significant decrease in all indicators representing the quality of life in patients with cervical dystonia was revealed compared with respondents without dystonic hyperkinesis. As a chronic disease, cervical dystonia leads to psycho-physiological stress, which significantly impairs the quality of life of patients. Significant gender differences were identified: women from the groups of cervical dystonia and cervicalgia were more often exposed to psychological deprivation and reduced physical activity than men from the same groups.Цель. Изучить физические и психологические составляющие качества жизни больных, страдающих цервикальной дистонией.Материалы и методы. Обследованы 170 респондентов: 120 пациентов с цервикальной дистонией составили основную группу, 50 человек включены в группу контроля – респонденты с цервикалгиями различного генеза. Диагноз цервикальной дистонии установлен клинически, согласно единым критериям по диагностике и лечению дистонии, принятым в 2011 г. Европейской федерацией неврологических обществ и Обществом двигательных расстройств (European Federation of Neurological Societies / Movement Disorders Society, EFNS / MDS). Болевой синдром в шейном отделе позвоночника у группы контроля был вызван дегенеративным процессом и подтвержден рентгенографическим обследованием и (или) магнитно-резонансной томографией. В рамках проводимого нами исследования определялось качество жизни у мужчин и женщин в обеих группах с помощью опросника SF-36 с изучением параметров физического и психологического благополучия.Результаты и заключение. Установлено достоверно значимое влияние цервикальной дистонии на соматические и психические параметры качества жизни как у мужчин, так и у женщин. Выявлено достоверное снижение всех показателей качества жизни у больных цервикальной дистонией по сравнению с респондентами, не имеющих дистонического гиперкинеза. Цервикальная дистония как хроническое заболевание приводит к психофизиологическому напряжению, что значительно ухудшает качество жизни больных. Выявлены достоверные гендерные внутригрупповые различия: женщины из групп цервикальной дистонии и цервикалгий в большей степени подвержены психологической депривации и снижению физической деятельности, чем мужчины из этих же групп

System Approach to the Development of Intelligent Complexes of Oncological Diagnostics

The system approach to the development of intellectual complexes in cancer diagnosis are discussed in the article. Distinctive features of this approach: the participation of pathologist at the stage of description of recognizable images (the description is based on traditional assessments of quality informative features of tumors); the set of the most similar probabilistic diagnoses is forming on the classification stage of recognition; final histological diagnosis is made by pathologist. The proposed approach has been successfully tested in clinical practice. Keywords: image processing, image description, image classification, pattern recognition, qualitative attributes of tumor images, interactive recognition, cancer diagnosis, decision support syste

Vitamin D (steroid hormone) and the nervous system diseases (literature review)

The present review aims to summarize the activities of vitamin D effects on the nervous system and to clarify a vitamin D role in brain diseases, in the pathogenesis or as a serum biomarker for the disease development and severity. Objective: correlation between chronic nervous system diseases and vitamin D level. Methods: a literature research in PubMed and in Russian electronic resources by keywords: vitamin D, brain diseases, chronic nervous system diseases. Results. Vitamin D as a neurosteroid hormone stimulates cerebral activity in both adult and embryonic brain regulates the activity of neural circuits which are responsible for locomotor, reward-dependent and emotional behavior. Patients with autism spectrum disorders, schizophrenia, Alzheimer disease, multiple sclerosis, Parkinson disease and sleep disorders have been shown to have low level of vitamin D. Discussion. Data are controversial, a further study of vitamin D hypovitaminosis significance is essential for the nervous system chronic diseases manifestation and evaluation of the vitamin D dietary supplement efficiency in patients with the nervous system pathology

Geometry and material effects in Casimir physics - Scattering theory

We give a comprehensive presentation of methods for calculating the Casimir force to arbitrary accuracy, for any number of objects, arbitrary shapes, susceptibility functions, and separations. The technique is applicable to objects immersed in media other than vacuum, to nonzero temperatures, and to spatial arrangements in which one object is enclosed in another. Our method combines each object's classical electromagnetic scattering amplitude with universal translation matrices, which convert between the bases used to calculate scattering for each object, but are otherwise independent of the details of the individual objects. This approach, which combines methods of statistical physics and scattering theory, is well suited to analyze many diverse phenomena. We illustrate its power and versatility by a number of examples, which show how the interplay of geometry and material properties helps to understand and control Casimir forces. We also examine whether electrodynamic Casimir forces can lead to stable levitation. Neglecting permeabilities, we prove that any equilibrium position of objects subject to such forces is unstable if the permittivities of all objects are higher or lower than that of the enveloping medium; the former being the generic case for ordinary materials in vacuum.Comment: 44 pages, 11 figures, to appear in upcoming Lecture Notes in Physics volume in Casimir physic