Body mass composition and dietary habits in adolescents with polycystic ovary syndrome

Objectives: The aim of the present study is to assess differences in body composition between female participants in the study group who suffer from PCOS versus a healthy control group. Material and methods: The study included 85, 14–22-year-old, female participants. Participants belonged to one of two groups. Thirty seven participants with a diagnosis of PCOS were in the clinical group, and 48 participants were in the healthy control group with no prior diagnosis of PCOS. Results: A statistically significant difference between groups was found in their answer regarding diet. A correlation was found between the body fat index and the use of dieting among participants; participants with a lower body fat index (in kilograms) were less likely to be on a diet. Conclusions: The young female participants with PCOS were shown to have similar body composition to age-matched healthy controls. However, the clinical group with PCOS reported more frequent use of dieting, with less use of exercise

Elevated glycodelin-A concentrations in serum and peritoneal fluid of women with ovarian endometriosis

The aim of this study was to evaluate serum and peritoneal fluid (PF) glycodelin-A concentrations in women with ovarian endometriosis. Ninety-nine matched pairs of serum and PF samples were included in our study. The case group comprised 57 women with ovarian endometriosis and the control group 42 healthy women undergoing sterilization or patients with benign ovarian cysts. Glycodelin-A concentrations were measured using ELISA. Endometriosis patients had significantly higher serum and PF glycodelin-A concentrations compared to controls, and this increase was observed in both proliferative and secretory cycle phases. Glycodelin-A concentrations were more than 10-fold higher in PF than in serum and correlated with each other. Intensity and frequency of menstrual pain positively correlated with glycodelin-A concentrations. Sensitivity and specificity of glycodelin-A as a biomarker for ovarian endometriosis were 82.1% and 78.4% in serum, and 79.7% and 77.5% in PF, respectively. These results indicate that Glycodelin-A has a potential role as a biomarker to be used in combination with other, independent marker molecules