78 research outputs found

    Physical investigation of copper thin film prepared by sputtering

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    Copper thin films have been deposited by sputtering. The simulation results show that most of deposited atoms on the substrate have kinetic energy ranging between 1 and 1.5 eV which leads to the deterioration of the crystalline quality, the impact angle between 10°- 70° and 100°-160°, with a peak at 40° and 150°, the oblique incidences of sputtered atoms on the substrate give films with porous and columnar microstructures. For higher pressure theses distributions are more uniforms leading to the uniformity of the obtained thin film which paid a great attention in the industry. These results are in accordance with numerical and experimental ones obtained in others works

    Alterations of Multipotent Mesenchymal Stromal Cells Induced by Interaction with Allogeneic Lymphocytes In Vitro

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    Multipotent mesenchymal stromal cells (MSCs) are widely used for cell therapy. Treatment with interferon-γ (IFNγ) increases the immunomodulating properties of MSCs. When administered intravenously, MSCs interact with lymphocytes. It is impossible to follow the fate of MSCs in the recipient organism. The aim of this study was to investigate the properties of MSCs after their interaction with lymphocytes in vitro. Bone marrow MSCs were co-cultured for 4 days with activated and non-activated lymphocytes. A portion of the MSCs was pretreated with IFNγ. HLA-DR expression on the MSCs increased when these cells were co-cultured with lymphocytes and after they were treated with IFNγ. The activated lymphocytes induced significantly higher HLA-DR expression levels than did IFNγ treatment. IFNγ increased the viability of MSCs when these cells were co-cultured with lymphocytes. The immunomodulating properties of MSCs were amplified after IFNγ priming and co-cultivation with lymphocytes; therefore, this amplification was not dependent on the IFNγ source. IFNγ treatment and lymphocyte interactions induced increases in the relative expression levels (RELs) of ICAM1 and factors involved in immunomodulation in the MSCs. IFNγ stabilizes MSCs while maintaining their viability. The data suggest that MSCs obtained from the hematopoietic cells donor or autologous should be used for cell therapy

    Hematopoietic and Stromatic Cells-Predecessors in Medulla Prol onged Structure

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    Available from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

    Physical investigation of copper thin film prepared by sputtering

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    434-439Copper thin films have been deposited by sputtering. The simulation results show that most of deposited atoms on the substrate have kinetic energy ranging between 1 and 1.5 eV which leads to the deterioration of the crystalline quality, the impact angle between 10°- 70° and 100°-160°, with a peak at 40° and 150°, the oblique incidences of sputtered atoms on the substrate give films with porous and columnar microstructures. For higher pressure theses distributions are more uniforms leading to the uniformity of the obtained thin film which paid a great attention in the industry. These results are in accordance with numerical and experimental ones obtained in others works

    What do we know about the participation of hematopoietic stem cells in hematopoiesis? [version 1; referees: 2 approved, 1 approved with reservations]

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    The demonstrated presence in adult tissues of cells with sustained tissue regenerative potential has given rise to the concept of tissue stem cells. Assays to detect and measure such cells indicate that they have enormous proliferative potential and usually an ability to produce all or many of the mature cell types that define the specialized functionality of the tissue. In the hematopoietic system, one or only a few cells can restore lifelong hematopoiesis of the whole organism. To what extent is the maintenance of hematopoietic stem cells required during normal hematopoiesis? How does the constant maintenance of hematopoiesis occur and what is the behavior of the hematopoietic stem cells in the normal organism? How many of the hematopoietic stem cells are created during the development of the organism? How many hematopoietic stem cells are generating more mature progeny at any given moment? What happens to the population of hematopoietic stem cells in aging? This review will attempt to describe the results of recent research which contradict some of the ideas established over the past 30 years about how hematopoiesis is regulated

    Tracts of Ku and C-band antennas for perspective communication satellites

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    The review of results of designing with the help of the topological synthesis technique and results of tract tests for the COUPON, YAMAL, LMI and other satellites is given in this paper
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