Ajagallika treated with Pratisaraneeya Kshara Karma - A Case Report

Kshudra Rogas are less severe diseases explained in Ayurvedic classics by different Acharyas. It is called Kshudra due to alpadosha (mild cause), alpalinga (mild symptoms) and alpachikitsa (mild treatment).[1] Ajagallika is one among the Kshudrarogas mentioned in Ayurvedic Classics.[2] It usually occurs in children.[3] But it can also occur in adults.[4] In the present study Ajagallika was treated with Pratisaraneeya Ksharakarma which is the line of treatment mentioned for Ajagallika in the text Chakradatta

Ayurvedic management of Diabetic Foot Ulcer - A Case Study

There are 424.9 million adults estimated to currently have diabetes globally.[1] Diabetic patients have an inherent risk of foot problems. Globally every 30 seconds, a major amputation occurs; 85% of which are preceded by trivial foot lesions.[2] In Ayurvedic literature, it is explained that Pidakas are formed in Adhoshaka in patients with Prameha due to the weakness of Rasayanis of lower limbs.[3] Such Pidakas if neglected over a period of time, without treatment will undergo Paaka and form a Vrana. Acharya Sushruta has described Shashti Upakramas (60 modalities) for the successful management of Vranas. Among them this article highlights the use of Shodhana, Kshara Varma, Chedana, Ropana and Bandhana Upakramas in the management of Diabetic Foot Ulcer/ Madhumehajanya Dushtavrana and also the need of Shastrakarma (surgical intervention) at the right time. In this study, Triphala Kashaya Avagaha and Pratisaraneeya kshara Karma for Vranashodhana, Chedana Karma followed by Ropana with Jatyaditaila was carried out. The course of treatment carried out brought about Dushtavranaavastha to Shuddhavranaavastha

A Single Case Study on treatment of Ileocaecal Tuberculous Sinus with Kadali Kshara Varti

Abdominal tuberculosis (TB) is an uncommon affliction in adolescence. It is usually associated with pulmonary tuberculosis. The disease is caused by lymphohaematogenous spread after primary infection in the lung or ingestion of infected sputum and has a typically nonspecific presentation. The occurrence of ileocaecal TB is probably from the contiguous spread of an abdominal focus or mesenteric lymph node. Ileocaecal TB is a rare entity, with very few reported cases in the literature. We report here a case of abdominal TB that manifested in the infection of an abdominal wall resulting in sinus at inguinal region and there by highlighting the Ayurvedic management of abdominal sinus by the use of Kshara Varti. Kshara Varti is the chief modality in the treatment in the Ayurvedic science and has been explained in Nadivrana

Understanding of Vrikka Vidradhi w.s.r. to Renal Abscess

charya Sushruta and Charaka, described Vrikka Vidradhi under Abhyantara Vidradhi, Vrikka Vidradhi is also mentioned and reflect the symptom of Parshva Sankocha, and it can be correlated with Renal abscess. Renal Abscess is a collection of pus around kidney. Renal abscess is an uncommon disease caused by trauma and infection associated with kidney stone. Renal abscess is caused by infection with enteric gram-negative bacilli, Staphylococcus aureus is the etiologic agent in 90% of cortical abscess cases. Renal abscesses most commonly occur in individuals with diabetes mellitus with or without urinary tract obstruction. Common symptoms in patients with renal corticomedullary abscess include fever, chills, nausea / vomiting and flank or abdominal pain. Percutaneous drainage plus parenteral antibiotics is indicated as the initial treatment for abscesses 3-5cm in size. In cases that involve perirenal abscess or infected urinoma, also place a percutaneous perirenal drain. Hence an attempt is made to understand Vrikka Vidhradi in relation to renal abscess

Management of Fistula In Ano with Ksharasutra - A Case Study

Fistula in ano is a disease known to the humanity since ancient times. For reasons that are unknown, non specific anal fistula are more common in men than women. The overall incidence is about nine cases per 100000 population per year in western Europe, and those in there third, fourth and fifth decades of life are most commonly affected. It is a chronic illness which is, though not fatal but quite discomfirting and troublesome to the patient and often puts deep impact on the quality of life of a patient. Despite many advances in medical field, it still poses big challenge to the surgeon as there is no suitable curative treatment available so far. For the same reason, Sushruta (500BC) has aptly described this disease as one of the Ashtamahagada. He was first person to describe, etiology, clinical feature and management of Bhagandara. He described Ksharasutra therapy in Bhagandara. A Female patient of age 65 years history of Ischiorectal abscess before 1month, she came on 10-7-2019 with the complaint of itching, pus discharge, mild pain in perianal region. Patient was a diagnosed case of Diabetes mellitus from 8years, Hypertension from 4 years, after investigations and local examination, patient was planned and treated with Ksharasutra

Understanding the concept of Marma and their clinical applicaion in Shalya Tantra w.s.r. to Vital points

Marma therapy is the original point system of healing in the body. “Marma” come from the sanskrit “Mru” and which means “To kill” the 107 Marma points are categorised in terms of their effect on the vitality of the body. Marma is one of the unique and important topics discussed in Ayurveda. It plays an important role in surgery. Hence it is rightly called as Shalya Vishayardha. Marma plays a significant clinical role and may be correlated to the Acupressure/Acupuncture. Marma are the critical points of body associated with different organs and nerves. Ayurveda describe use of Marma therapy for various diseases and identification of Marma points which is to be cured, since injury to these Marma points may causes serious harmful effect. Different types of muscles, veins, bones, ligaments and joints meets with each other at the Marma point thus these points acts as a physiological junction. Discussion of Marma points is found in most of the great texts of Ayurveda but the most famous text to explore the subject is the Sushruta Samhita. Vaidya Sushruta described ‘the locations of the Marma points, as well as how they influence Prana. He stated that it is important for the surgeon to have knowledge of these points for the purpose of avoiding them, so as to cut into them could result in a catastrophic outcome. This article summarizes various perspectives of Marma and their clinical importance as per Ayurveda

Clinical study to evaluate the efficacy of Yavakshara with Varunaadi Kwatha Churna in Mutrashmari w.s.r to Urolithiasis - A Case Study

Mutrashmari is one of the commonest diseases of Mutravaha Srotas, Acharya Sushruta described it as one of the Ashta-Mahagadas and considered as “Yama” because it gives intolerable pain. Charaka mentioned Ashmari as one of Bastimarmashritha Vyadhi. In modern science it is correlated with Urolithiasis. The incidence rate of Calculi varies as per geographical distribution, sex and age. Generally, men are more affected than women in the ratio of 3:1. The highest incidence of Urolithiasis occurs between the ages of 30-50 years. In Ayurveda various conservative medicine are mentioned for the management Mutrashmari with less side effect, easily available, cost effective and minimum recurrences of stone formation. In this case report 40 years male patient visited OPD of Shalya Tantra with complaint of abdominal pain (radiating pain from loin to groin), nausea and burning micturation. The USG report showed two calculi measuring 6mm and 4mm seen in the left kidney, no evidence of hydronephrosis, 3 calculi measuring 6mm, 5mm and 4mm are seen in the right kidney, and right kidney shows mild HUN due to calculus measuring 5mm in the VUJ. The patient was treated with Yavakshara 3 Gunja Pramana twice a day with 2 Phala of prepared Varunaadi Kashaya for a period of 1 month. At the end of treatment and also in follow up period after 15 days patient got relief in signs and symptoms and USG report showed no evidence calculi in both the kidneys

Genome Sequence of Fusobacterium nucleatum Subspecies Polymorphum — a Genetically Tractable Fusobacterium

Fusobacterium nucleatum is a prominent member of the oral microbiota and is a common cause of human infection. F. nucleatum includes five subspecies: polymorphum, nucleatum, vincentii, fusiforme, and animalis. F. nucleatum subsp. polymorphum ATCC 10953 has been well characterized phenotypically and, in contrast to previously sequenced strains, is amenable to gene transfer. We sequenced and annotated the 2,429,698 bp genome of F. nucleatum subsp. polymorphum ATCC 10953. Plasmid pFN3 from the strain was also sequenced and analyzed. When compared to the other two available fusobacterial genomes (F. nucleatum subsp. nucleatum, and F. nucleatum subsp. vincentii) 627 open reading frames unique to F. nucleatum subsp. polymorphum ATCC 10953 were identified. A large percentage of these mapped within one of 28 regions or islands containing five or more genes. Seventeen percent of the clustered proteins that demonstrated similarity were most similar to proteins from the clostridia, with others being most similar to proteins from other gram-positive organisms such as Bacillus and Streptococcus. A ten kilobase region homologous to the Salmonella typhimurium propanediol utilization locus was identified, as was a prophage and integrated conjugal plasmid. The genome contains five composite ribozyme/transposons, similar to the CdISt IStrons described in Clostridium difficile. IStrons are not present in the other fusobacterial genomes. These findings indicate that F. nucleatum subsp. polymorphum is proficient at horizontal gene transfer and that exchange with the Firmicutes, particularly the Clostridia, is common